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anti-ZFP-42/REX-1 antibody :: Mouse anti-Human  ZFP-42/REX-1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS851010
Testing Data
Unit / Price
0.1 mL  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ZFP-42/REX-1, Monoclonal Antibody

 Also Known As   

ZFP-42/REX-1 Antibody

 Product Gene Name   

anti-ZFP-42/REX-1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    614572
 3D Structure    ModBase 3D Structure for Q96MM3
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 Clonality    Monoclonal
 Clone Number    E7-B7-A7
 Host    Mouse
 Species Reactivity    Human 
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 Specificity    This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near C-terminal residues of zfp-42.
 Form/Format    Mouse monoclonal IgG1 in 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol. Preservative: 0.05% Sodium Azide.
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 Cellular Localization    Cell nuclear
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 Preparation and Storage    Store at 4 degree C after thawing. Aliquot store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
 Other Notes    Small volumes of anti-ZFP-42/REX-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ZFP-42/REX-1 antibody

   Background: REX-1/Zfp-42 was initially described as a factor present at high levels in murine F9 teratocarcinoma stem cells (EC).The Rex-1 (Zfp-42) gene encodes a zinc finger family transcription factor which is highly expressed in mouse and human embryonic stem cells. It is one of several gene markers used to identify human stem cells. REX-1 is found in spermatocytes and primary oocytes during replication and may play a role in meiosis. Recently, the expression of REX-1 in normal epithelial tissue cells has been demonstrated.
 Product Categories/Family for anti-ZFP-42/REX-1 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-ZFP-42/REX-1 antibody   

Western Blot (WB) 

 Application Notes for anti-ZFP-42/REX-1 antibody    WB: 1:1,000
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 Testing Data of anti-ZFP-42/REX-1 antibody    anti-ZFP-42/REX-1 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for ZFP-42/REX-1. It may not necessarily be applicable to this product.
 NCBI GI #    89179323
 NCBI GeneID    132625
 NCBI Accession #    NP_777560.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_174900.3 [Other Products]
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 UniProt Primary Accession #    Q96MM3 [Other Products]
 UniProt Secondary Accession #    Q8WXE2; D3DP65 [Other Products]
 UniProt Related Accession #    Q96MM3 [Other Products]
 Molecular Weight    38kDa
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 NCBI Official Full Name    zinc finger protein 42 homolog
 NCBI Official Synonym Full Names    ZFP42 zinc finger protein
 NCBI Official Symbol    ZFP42 [Similar Products]
 NCBI Official Synonym Symbols   
REX1; ZNF754
[Similar Products]
 NCBI Protein Information    zinc finger protein 42 homolog; REX-1; hREX-1; zfp-42; zinc finger protein 754; REX1 transcription factor; reduced expression protein 1
 UniProt Protein Name    Zinc finger protein 42 homolog
 UniProt Synonym Protein Names   
Reduced expression protein 1; REX-1; hREX-1; Zinc finger protein 754
 UniProt Gene Name    ZFP42 [Similar Products]
 UniProt Synonym Gene Names    REX1; ZNF754; Zfp-42; REX-1; hREX-1 [Similar Products]
 UniProt Entry Name    ZFP42_HUMAN
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 UniProt Comments for ZFP-42/REX-1    ZFP42: Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: DNA-binding; C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 4q35.2

Cellular Component: protein complex; cytoplasm; nucleus

Molecular Function: sequence-specific DNA binding; metal ion binding; transcription factor activity

Biological Process: meiosis; transcription, DNA-dependent; regulation of transcription, DNA-dependent; in utero embryonic development; male gonad development; female gonad development; spermatid development
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Product References and Citations for anti-ZFP-42/REX-1 antibody

   Mongan N.P., Martin K.M., Gudas L.J.; "The putative human stem cell marker, Rex-1 (Zfp42): structural classification and expression in normal human epithelial and carcinoma cell cultures."; Mol. Carcinog. 45:887-900(2006).
Raman J.D., Mongan N.P., Liu L., Tickoo S.K., Nanus D.M., Scherr D.S., Gudas L.J.; "Decreased expression of the human stem cell marker, Rex-1 (zfp-42), in renal cell carcinoma."; Carcinogenesis 27:499-507(2006).
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 Research Articles on ZFP-42/REX-1    1. Results show that a novel pluripotency regulator, REX1, is essential for pluripotency and reprogramming.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ZFP-42/REX-1 antibodyPathways associated with anti-ZFP-42/REX-1 antibody
 Reference Product  PubMed Publications
 POU5F1 antibody  >34 publications with ZFP-42/REX-1 and POU5F1
 OCT4 antibody  >21 publications with ZFP-42/REX-1 and OCT4
 RNF2 antibody  >1 publications with ZFP-42/REX-1 and RNF2
 RYBP antibody  >1 publications with ZFP-42/REX-1 and RYBP
 RING1 antibody  >1 publications with ZFP-42/REX-1 and RING1
 YAF2 antibody  >1 publications with ZFP-42/REX-1 and YAF2
 Products by Pathway  Pathway Diagram
 Cardiac Progenitor Differentiation Pathway antibodies  Cardiac Progenitor Differentiation Pathway Diagram
Diseases associated with anti-ZFP-42/REX-1 antibodyOrgans/Tissues associated with anti-ZFP-42/REX-1 antibody
 Disease Name  Pubmed Publications
 Skin Neoplasms Antibodies  >1 publications with ZFP-42/REX-1 and Skin Neoplasms
 Eye Abnormalities Antibodies  >1 publications with ZFP-42/REX-1 and Eye Abnormalities
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with ZFP-42/REX-1 and Drug-Related Side Effects and Adverse Reactions
 Nervous System Diseases Antibodies  >1 publications with ZFP-42/REX-1 and Nervous System Diseases
 Inflammation Antibodies  >1 publications with ZFP-42/REX-1 and Inflammation
 Brain Diseases Antibodies  >1 publications with ZFP-42/REX-1 and Brain Diseases
 Fibrosis Antibodies  >1 publications with ZFP-42/REX-1 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >20 publications with ZFP-42/REX-1 and Embryonic Tissue
 Placenta Antibodies  >5 publications with ZFP-42/REX-1 and Placenta
 Epididymis Antibodies  >1 publications with ZFP-42/REX-1 and Epididymis
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