Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ZFP36 rightarrow Monoclonal ZFP36  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Surfactant Associated Protein B (SPB) Recombinant Protein
 • Aldehyde Dehydrogenase 1A1 (ALDH1A1) Antibody
 • Serine Peptidase Inhibitor Kazal Type 5 (SPINK5) Recombinant Protein
 • Flavodoxin Recombinant Protein
 • Phosphomannomutase 1 (PMM1) Recombinant Protein
 • A Disintegrin and Metalloprotease 15 (ADAM15) ELISA Kit
 • ADH1B Antibody
 • Metalloproteinase 13 (MMP-13) ELISA Kit
 • Oxazepam Antibody
 • Carboxypeptidase A2 (CPA2) Antibody
 • Skeletal Muscle Actinin-alpha (SM ACTININ-alpha) ELISA Kit
 • Isocitrate Dehydrogenase (CDH) Recombinant Protein
 • Neutrophil Elastase, Lyophilized (ELANE) Protease
 • pigment epithelium-derived factor, PEDF ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ZFP36 antibody :: Mouse ZFP36 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS834746
Unit / Price
0.1 mL  /  $515 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ZFP36, Monoclonal Antibody

 Also Known As   

ZFP36 antibody

 Product Synonym Names    Monoclonal ZFP36; Anti-ZFP36; Zinc finger protein 36 C3H type homolog; TTP; G0S24; RNF162A; TIS11; NUP475; Growth factor-inducible nuclear protein NUP475; Zinc finger protein 36 homolog; ZFP36; ZFP 36; ZFP-36
 Product Gene Name   

anti-ZFP36 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    603896
 3D Structure    ModBase 3D Structure for Q13144
Section Bar
 Clonality    Monoclonal
 Isotype    IgG1
 Clone Number    1G9
 Host    Mouse
 Species Reactivity    Human, Dog, Monkey
Section Bar
 Purity/Purification    ZFP36 antibody was purified by affinity chromatography.
 Form/Format    Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
 Concentration    500 ug-1 mg/ml (lot specific)
Section Bar
 Biological Significance    ZFP36 is a probable regulatory protein with a novel zinc finger structure involved in regulating the response to growth factors. It has been experimentally shown to be able to bind zinc.
 Immunogen    ZFP36 antibody was raised in mouse using a full length recombinant protein of human ZFP36 (NP_003898) produced in HEK293T cells, as the immunogen.
Section Bar
 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-ZFP36 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-ZFP36 antibody

   Mouse monoclonal ZFP36 antibody
 Product Categories/Family for anti-ZFP36 antibody    Cell Biology
 Applications Tested/Suitable for anti-ZFP36 antibody   

Flow Cytometry (FC/FACS), Western Blot (WB)

 Application Notes for anti-ZFP36 antibody    FC: 1:100
WB: 1:1000-2000
Section Bar
 Flow Cytometry (FC/FACS) of anti-ZFP36 antibody    Flow Cytometric analysis of HEK293T cells transfected with either recombinant ZFP36 protein (red) or empty vector (blue) stained using ZFP36 antibody
anti-ZFP36 antibody Flow Cytometry (FC/FACS) (FC/FACS) image
Section Bar
 Western Blot (WB) of anti-ZFP36 antibody    Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant ZFP36 protein (Right) or empty vector (Left) detected with ZFP36 antibody
anti-ZFP36 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ZFP36. It may not necessarily be applicable to this product.
 NCBI GI #    83267879
 NCBI GeneID    8893
 NCBI Accession #    NP_003898 [Other Products]
 NCBI GenBank Nucleotide #    NM_003907.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q13144 [Other Products]
 UniProt Secondary Accession #    Q541Z1; Q96D04 [Other Products]
 UniProt Related Accession #    Q13144 [Other Products]
 Molecular Weight    80,380 Da
Table BarTOPTable Bar
 NCBI Official Full Name    translation initiation factor eIF-2B subunit epsilon
 NCBI Official Synonym Full Names    eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
 NCBI Official Symbol    EIF2B5 [Similar Products]
 NCBI Official Synonym Symbols   
CLE; CACH; LVWM; EIF-2B; EIF2Bepsilon
[Similar Products]
 NCBI Protein Information    translation initiation factor eIF-2B subunit epsilon
 UniProt Protein Name    Translation initiation factor eIF-2B subunit epsilon
 UniProt Synonym Protein Names   
eIF-2B GDP-GTP exchange factor subunit epsilon
 Protein Family    mRNA decay activator protein
 UniProt Gene Name    EIF2B5 [Similar Products]
 UniProt Synonym Gene Names    EIF2BE [Similar Products]
 UniProt Entry Name    EI2BE_HUMAN
Section Bar
 NCBI Summary for ZFP36    This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009]
Section Bar
 UniProt Comments for ZFP36    eIF2B-epsilon: eukaryotic translation initiation factor 2B, subunit 5. A translational regulatory protein that functions in the early steps of protein synthesis by catalyzing the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Mutation in EIF2B5 causes childhood ataxia with central nervous system hypomyelination/ vanishing white matter leukodystrophy.

Protein type: Translation initiation; Translation

Chromosomal Location of Human Ortholog: 3q27.1

Cellular Component: eukaryotic translation initiation factor 2B complex; cytoplasm; nucleus; cytosol

Molecular Function: protein binding; translation initiation factor binding; guanyl-nucleotide exchange factor activity; translation initiation factor activity

Biological Process: myelination; response to peptide hormone stimulus; translation; astrocyte development; positive regulation of translational initiation; cellular protein metabolic process; astrocyte differentiation; ovarian follicle development; response to heat; translational initiation; response to glucose stimulus; gene expression; negative regulation of translation initiation in response to stress; oligodendrocyte development; positive regulation of GTPase activity

Disease: Leukoencephalopathy With Vanishing White Matter
Table BarTOPTable Bar
 Research Articles on ZFP36    1. Missense mutations in EIF2B5 are associated with multiple sclerosis.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-ZFP36 antibodyPathways associated with anti-ZFP36 antibody
 Reference Product  PubMed Publications
 EIF2B2 antibody  >37 publications with ZFP36 and EIF2B2
 EIF2B1 antibody  >36 publications with ZFP36 and EIF2B1
 EIF2B4 antibody  >7 publications with ZFP36 and EIF2B4
 EIF2B3 antibody  >7 publications with ZFP36 and EIF2B3
 Products by Pathway  Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 MicroRNAs In Cardiomyocyte Hypertrophy Pathway antibodies  MicroRNAs In Cardiomyocyte Hypertrophy Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 RNA Transport Pathway antibodies  RNA Transport Pathway Diagram
 Recycling Of EIF2:GDP Pathway antibodies  Recycling Of EIF2:GDP Pathway Diagram
 Translation Pathway antibodies  Translation Pathway Diagram
 Translation Factors Pathway antibodies  Translation Factors Pathway Diagram
Diseases associated with anti-ZFP36 antibodyOrgans/Tissues associated with anti-ZFP36 antibody
 Disease Name  Pubmed Publications
 Neurodegenerative Diseases Antibodies  >12 publications with ZFP36 and Neurodegenerative Diseases
 Neurologic Manifestations Antibodies  >12 publications with ZFP36 and Neurologic Manifestations
 Seizures Antibodies  >3 publications with ZFP36 and Seizures
 Cognition Disorders Antibodies  >2 publications with ZFP36 and Cognition Disorders
 Vascular Diseases Antibodies  >2 publications with ZFP36 and Vascular Diseases
 Inflammation Antibodies  >2 publications with ZFP36 and Inflammation
 Memory Disorders Antibodies  >1 publications with ZFP36 and Memory Disorders
 Carcinoma Antibodies  >1 publications with ZFP36 and Carcinoma
 Neurobehavioral Manifestations Antibodies  >1 publications with ZFP36 and Neurobehavioral Manifestations
 Neoplasms, Experimental Antibodies  >1 publications with ZFP36 and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >31 publications with ZFP36 and Brain
 Nerve Antibodies  >9 publications with ZFP36 and Nerve
 Blood Antibodies  >3 publications with ZFP36 and Blood
 Vascular Antibodies  >2 publications with ZFP36 and Vascular
 Muscle Antibodies  >1 publications with ZFP36 and Muscle
 Lung Antibodies  >1 publications with ZFP36 and Lung
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions