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anti-a/b SNAP antibody :: Mouse a/b SNAP Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS395170
Western Blot/Blotting
Unit / Price
0.1 mg  /  $325 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

a/b SNAP, Monoclonal Antibody

★Popular Item★
 Also Known As   

a/b SNAP

 Product Synonym Names    alpha/beta SNAP; mouse anti alpha/beta soluble NSF attachment protein
 Product Gene Name   

anti-a/b SNAP antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 19; NC_000019.9 (47990891..48018515, complement). Location: 19q13.33
 OMIM    603215
 3D Structure    ModBase 3D Structure for P54920
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 Clonality    Monoclonal
 Isotype    IgG2b
 Clone Number    16D1
 Host    Mouse
 Species Reactivity    Human, Rat, Bovine, Chicken
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 Form/Format    20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, pH 7.5
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 Immunogen    Recombinant human alpha SNAP
 Positive Control    Rat brain
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 Preparation and Storage    Product should be stored at -20 degree C. Aliquot to avoid freeze/thaw cycles
 Other Notes    Small volumes of anti-a/b SNAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-a/b SNAP antibody

   38 kDa SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-
 Product Categories/Family for anti-a/b SNAP antibody    Monoclonal Antibody; Neuronal Signaling
 Applications Tested/Suitable for anti-a/b SNAP antibody   

Western Blot (WB)

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 Western Blot/Blotting of anti-a/b SNAP antibody    Western blot (10% SDS-PAGE) of chicken brain (lane 1), chicken kidney (lane 2), rat brain (lane 3) and rat kidney (lane 4) probed with clone 16D1 anti- / SNAP at 0.2 g/ml.
anti-a/b SNAP antibody Western Blot/Blotting (WB) image
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NCBI/Uniprot data below describe general gene information for a/b SNAP. It may not necessarily be applicable to this product.
 NCBI GI #    47933379
 NCBI GeneID    8775
 NCBI Accession #    NP_003818.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003827.3 [Other Products]
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 UniProt Primary Accession #    P54920 [Other Products]
 UniProt Secondary Accession #    Q96IK3; Q9BVJ3; A8K879 [Other Products]
 UniProt Related Accession #    P54920 [Other Products]
 Molecular Weight    38
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 NCBI Official Full Name    alpha-soluble NSF attachment protein
 NCBI Official Synonym Full Names    N-ethylmaleimide-sensitive factor attachment protein, alpha
 NCBI Official Symbol    NAPA [Similar Products]
 NCBI Official Synonym Symbols   
SNAPA
[Similar Products]
 NCBI Protein Information    alpha-soluble NSF attachment protein; alpha-SNAP
 UniProt Protein Name    Alpha-soluble NSF attachment protein
 UniProt Synonym Protein Names   
N-ethylmaleimide-sensitive factor attachment protein alpha
 UniProt Gene Name    NAPA [Similar Products]
 UniProt Synonym Gene Names    SNAPA; SNAP-alpha [Similar Products]
 UniProt Entry Name    SNAA_HUMAN
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 NCBI Summary for a/b SNAP    This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
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 UniProt Comments for a/b SNAP    Function: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

Subunit structure: Interacts with PRKCABP, and disrupts the interaction between GRIA2 and PRKCABP, leading to the internalization of GRIA2. Found in a complex with VAMP8

By similarity. Component of a SNARE-like complex that contains at least ZW10, USE1L, RINT1, STX18 and NAPA/SNAP-alpha. Interacts with VTI1A. Interacts with STX12

By similarity. Ref.7

Subcellular location: Membrane; Peripheral membrane protein.

Sequence similarities: Belongs to the SNAP family.
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 Research Articles on a/b SNAP    1. Study revealed a novel role for alphaSNAP as a negative regulator of autophagy that acts by enhancing mTOR signaling and regulating the integrity of the Golgi complex.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-a/b SNAP antibodyPathways associated with anti-a/b SNAP antibody
 Reference Product  PubMed Publications
 NSF antibody  >2 publications with a/b SNAP and NSF
 SNAP25 antibody  >1 publications with a/b SNAP and SNAP25
 VAMP2 antibody  >1 publications with a/b SNAP and VAMP2
 STX1A antibody  >1 publications with a/b SNAP and STX1A
 Products by Pathway  Pathway Diagram
 Clathrin Derived Vesicle Budding Pathway antibodies  Clathrin Derived Vesicle Budding Pathway Diagram
 Golgi Associated Vesicle Biogenesis Pathway antibodies  Golgi Associated Vesicle Biogenesis Pathway Diagram
 Membrane Trafficking Pathway antibodies  Membrane Trafficking Pathway Diagram
 Synaptic Vesicle Pathway antibodies  Synaptic Vesicle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Synaptic Vesicle Cycle Pathway antibodies  Synaptic Vesicle Cycle Pathway Diagram
 Trans-Golgi Network Vesicle Budding Pathway antibodies  Trans-Golgi Network Vesicle Budding Pathway Diagram
Diseases associated with anti-a/b SNAP antibodyOrgans/Tissues associated with anti-a/b SNAP antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >61 publications with a/b SNAP and Cardiovascular Diseases
 Nervous System Diseases Antibodies  >43 publications with a/b SNAP and Nervous System Diseases
 Neoplasms Antibodies  >39 publications with a/b SNAP and Neoplasms
 Drug Toxicity Antibodies  >30 publications with a/b SNAP and Drug Toxicity
 Poisoning Antibodies  >20 publications with a/b SNAP and Poisoning
 Kidney Diseases Antibodies  >18 publications with a/b SNAP and Kidney Diseases
 Breast Neoplasms Antibodies  >14 publications with a/b SNAP and Breast Neoplasms
 Inflammation Antibodies  >10 publications with a/b SNAP and Inflammation
 Adenocarcinoma Antibodies  >9 publications with a/b SNAP and Adenocarcinoma
 Disease Models, Animal Antibodies  >8 publications with a/b SNAP and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >134 publications with a/b SNAP and Blood
 Heart Antibodies  >61 publications with a/b SNAP and Heart
 Kidney Antibodies  >44 publications with a/b SNAP and Kidney
 Brain Antibodies  >34 publications with a/b SNAP and Brain
 Liver Antibodies  >25 publications with a/b SNAP and Liver
 Muscle Antibodies  >19 publications with a/b SNAP and Muscle
 Vascular Antibodies  >14 publications with a/b SNAP and Vascular
 Nerve Antibodies  >10 publications with a/b SNAP and Nerve
 Skin Antibodies  >9 publications with a/b SNAP and Skin
 Bone Antibodies  >8 publications with a/b SNAP and Bone
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