View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Mouse anti-Human b-Amyloid Peptide Monoclonal Antibody Catalog # MBS600139 Unit / Price 0.1 mg / $945 +1 FREE 8GB USB 5x0.1 mg / $4,070 +5 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name b-Amyloid Peptide, Monoclonal Antibody Full Product Name b-Amyloid Peptide Product Synonym Names Anti -b-Amyloid Peptide Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Monoclonal Isotype IgG1,k Clone Number 3G5 Host Mouse Species Reactivity Human Specificity Recognizes the 4-5kD b-amyloid peptide (b-AP). High concentrations of antibody will also react with A-a, B-a and g subunits of brinogen. Species Crossreactivity: human. Purity/Purification PurifiedPuri ed Form/Format Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide. Immunogen 28aa synthetic peptide derived from the b-amyloid peptide (aa1-28). Preparation and Storage May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Other Notes Small volumes of anti-b-Amyloid Peptide antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-b-Amyloid Peptide antibody The progressive deposition of insoluble amyloid protein plaques in speci c areas of the brain and its blood vessels is associated with a number of neuropathologies and is an early invariant feature of Alzheimer's disease. The major component of these protein plaques is a peptide of 39-42 amino acids derived from a group of 695-770 amino acid precursor proteins collectively referred to as the b-amyloid precursor protein (Beta-APP). b-APP is highly conserved in vertebrates; however, its normal function has not been well de ned. In each of the b-APPs, the b-Amyloid peptide (b-AP) is an internal peptide that begins about 99 residues from the carboxy-terminal end of the b-APP and extends from the extracellular domain into the middle of the hydrophobic, membrane spanning domain of the precursor protein. The precise mechanism whereby b-AP accumulates in brain remains poorly de ned. Product Categories/Family for anti-b-Amyloid Peptide antibody Antibodies; Abs to Amyloid Applications Tested/Suitable for anti-b-Amyloid Peptide antibody ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC) Application Notes for anti-b-Amyloid Peptide antibody Suitable for use in ELISA, Immunohistochemistry and Western Blot.Dilution: Immunohistochemistry (alcohol-fixed, parrafin embedded, frozen): ~10ug/ml It is nessessary to pretreat the tissue with trypsin digestion.Western Blot: 0.1-0.2ug/mlELISA: 0.5-1.0ug/ml Western Blot (WB) of anti-b-Amyloid Peptide antibody Western Blot analysis was performed on human samples (30 ug) of Alzheimer's Disease patient CSF sample (Lane 1) and corresponding normal CSF sample (Lane 2). The blots were probed with MBS600139 (2ug/ml) and detected by chemiluminescence using Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, HRP conjugate (0.4 µg/mL, 1:2500). An ~110kD band corresponding to beta-Amyloid was observed in Alzheimer's Disease patient CSF sample and a 35kD band was observed across both TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP