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anti-HLA-G antibody :: Mouse anti-Chicken b2-Microglobulin Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS602016 anti-HLA-G antibody
Unit / Price
0.5 mg  /  $610 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

b2-Microglobulin (HLA-G), Monoclonal Antibody

 Also Known As   

b2-Microglobulin (FITC) (B2M)

 Product Synonym Names    Anti -b2-Microglobulin (FITC) (B2M)
 Product Gene Name   

anti-HLA-G antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 6; NC_000006.11 (29794756..29798899). Location: 6p21.3
 3D Structure    ModBase 3D Structure for O02923
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 Clonality    Monoclonal
 Isotype    IgG1,k
 Clone Number    5K91
 Host    Mouse
 Species Reactivity    Chicken
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 Specificity    Recognizes the b2-microglobulin subunit (Mr ~14kD) of avian MHC Class I molecules. Also reacts with turkey b2-microglobulin.
 Purity/Purification    Purified
Purified
 Form/Format    Supplied as a liquid in PBS, 0.1% sodium azide. Conjugated to FITC.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-HLA-G antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HLA-G antibody

   Like their mammalian counterparts, avian MHC Class I molecules (also known as B-F antigens) consist of a highly polymorphic alpha-chain (Mr ~44kD) non-covalently bound to the invariant beta2-microglobulin subunit (Mr ~14kD). MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells.1-2
 Product Categories/Family for anti-HLA-G antibody    Antibodies; Abs to Serum Proteins
 Applications Tested/Suitable for anti-HLA-G antibody   

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

 Application Notes for anti-HLA-G antibody    Flow cytometry 1-2, , Immunoprecipitation 1-2, , Western blotting, , Immunohistochemistry, , Immunoaffinity chromatography
Dilution: Flow Cytometry: 1ug/10e6 cells
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NCBI/Uniprot data below describe general gene information for HLA-G. It may not necessarily be applicable to this product.
 NCBI GI #    188468
 NCBI GeneID    3135
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 UniProt Primary Accession #    O02923 [Other Products]
 UniProt Related Accession #    O02923; O02924; O02925; O02926; O02927; O02928; O02929; O19588; O19658; O19659 [Other Products]
 Molecular Weight    31,549 Da [Similar Products]
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 NCBI Official Full Name    b2 microglobulin
 NCBI Official Synonym Full Names    major histocompatibility complex, class I, G
 NCBI Official Symbol    HLA-G [Similar Products]
 NCBI Official Synonym Symbols   
MHC-G
[Similar Products]
 NCBI Protein Information    HLA class I histocompatibility antigen, alpha chain G; HLA G antigen; b2 microglobulin; OTTHUMP00000029218; OTTHUMP00000029220; OTTHUMP00000033527; OTTHUMP00000159507; HLA class I molecule; MHC class I antigen G; HLA-G histocompatibility antigen, class I, G
 UniProt Protein Name    HLA-G protein
 Protein Family    HLA class I histocompatibility antigen
 UniProt Gene Name    HLA-G [Similar Products]
 UniProt Entry Name    O02923_HUMAN
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 NCBI Summary for HLA-G    HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq]
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 UniProt Comments for HLA-G    Sequence similarities: Belongs to the MHC class I family. RuleBase RU004439
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 Research Articles on HLA-G    1. We found the production of HLA-G and HLA-E in a majority of cases of glioblastoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HLA-G antibodyPathways associated with anti-HLA-G antibody
 Reference Product  PubMed Publications
 LILRB1 antibody  >45 publications with HLA-G and LILRB1
 LILRB2 antibody  >33 publications with HLA-G and LILRB2
 KLRD1 antibody  >26 publications with HLA-G and KLRD1
 KIR2DL4 antibody  >22 publications with HLA-G and KIR2DL4
 TAP1 antibody  >14 publications with HLA-G and TAP1
 TAP2 antibody  >9 publications with HLA-G and TAP2
 B2M antibody  >4 publications with HLA-G and B2M
 Products by Pathway  Pathway Diagram
 Adaptive Immunity Signaling Pathway antibodies  Adaptive Immunity Signaling Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway antibodies  Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
Diseases associated with anti-HLA-G antibodyOrgans/Tissues associated with anti-HLA-G antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >254 publications with HLA-G and Neoplasms
 Carcinoma Antibodies  >108 publications with HLA-G and Carcinoma
 Adenocarcinoma Antibodies  >72 publications with HLA-G and Adenocarcinoma
 Skin Diseases Antibodies  >53 publications with HLA-G and Skin Diseases
 Neuroectodermal Tumors Antibodies  >49 publications with HLA-G and Neuroectodermal Tumors
 Leukemia Antibodies  >49 publications with HLA-G and Leukemia
 Melanoma Antibodies  >44 publications with HLA-G and Melanoma
 Inflammation Antibodies  >42 publications with HLA-G and Inflammation
 Nervous System Diseases Antibodies  >31 publications with HLA-G and Nervous System Diseases
 Lung Diseases Antibodies  >26 publications with HLA-G and Lung Diseases
 Organ/Tissue Name  Pubmed Publications
 Placenta Antibodies  >388 publications with HLA-G and Placenta
 Embryonic Tissue Antibodies  >167 publications with HLA-G and Embryonic Tissue
 Thymus Antibodies  >22 publications with HLA-G and Thymus
 Brain Antibodies  >22 publications with HLA-G and Brain
 Lung Antibodies  >21 publications with HLA-G and Lung
 Stomach Antibodies  >6 publications with HLA-G and Stomach
 Intestine Antibodies  >6 publications with HLA-G and Intestine
 Testis Antibodies  >4 publications with HLA-G and Testis
 Pancreas Antibodies  >3 publications with HLA-G and Pancreas
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