Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow Antibody rightarrow c-erbB-2/HER-2 rightarrow Monoclonal c-erbB-2/HER-2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • Goat Anti-Canine IgG (H+L) Secondary Antibody
 • U1-cyrtautoxin-As1c (U1-CUTX-As1c) Recombinant Protein
 • Glutathione S-transferase P (GSTP) ELISA Kit
 • Proteoglycan 4 (PRG4) ELISA Kit
 • Forkhead box protein L2 (Foxl2) Recombinant Protein
 • SMAD6 Antibody
 • Enrofloxacin Antibody
 • SNCgamma ELISA Kit
 • Augmenter of Liver Regeneration (ALR) ELISA Kit
 • Synuclein, Alpha (SNCa) ELISA Kit
 • vasodilator-stimulated phosphoprotein (VASP) ELISA Kit
 • Spliceosome RNA helicase DDX39B Antibody
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-c-erbB-2/HER-2 antibody :: Mouse c-erbB-2/HER-2 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS462228
Testing Data
Unit / Price
0.1 mg  /  $285 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

c-erbB-2/HER-2, Monoclonal Antibody

 Also Known As   

Mouse anti c-erbB-2/HER-2

 Product Synonym Names    Ms anti-c-erbB-2/HER-2; human epidermal growth factor Receptor 2 (Her-2); p185erbB2; MLN19; C-erbB-2; NEU proto-oncogene; Tyrosine kinase-type cell surface receptor HER2; CD340 antigen
 Product Gene Name   

anti-c-erbB-2/HER-2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Clonality    Monoclonal
 Isotype    IgG1, k
 Clone Number    SPM495
 Host    Mouse
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Specificity    This antibody recognizes Her-2 protein. It cross-reacts with human, rat and mouse. The other species was not tested.
 Purity/Purification    The Mouse IgG is purified by Isotyping-specific Affinity Purification.
 Form/Format    This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer
 Concentration    Size: 100 ug/200 ul (lot specific)
Section Bar
 Antigen Preparation    A synthetic peptide corresponding to the C-terminus of Her2 protein. This sequence is identical in human, mouse, and rat.
 Positive Control    SK-BR-3 cell lysate
 Cellular Location    Membrane
Section Bar
 Preparation and Storage    The antibodies are stable for 12 months from date of receipt when stored at -20 degree C to -70 degree C. The antibodies can be stored at 2 degree C-8 degree C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
 Other Notes    Small volumes of anti-c-erbB-2/HER-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar

Related Product Information for anti-c-erbB-2/HER-2 antibody

   Oncoprotein Her-2/Neu/ c-erbB-2 belongs to one of the four members of the ErbB receptor family. They are transmembrane receptor-like tyrosine kinases which can be autophosphorylated without ligand binding process when it is overexpressed in breast cancers. Her2 is an important biomarker in breast cancer diagnosis. The antibodies/ heregulin can suppress phosphorylation of HER2 on tyrosine Y1248. Endogenous anti-HER2 antibodies can effectively suppress HER2 kinase activity and downstream signaling to inhibit the transformed phenotype of HER2-expressing tumor cells. Thus, anti-Her2 antibodies have been used widely in the treatment of the breast cancer and other carcinomas.
 Applications Tested/Suitable for anti-c-erbB-2/HER-2 antibody   

ELISA, Western Blot, Immunohistochemistry

 Application Notes for anti-c-erbB-2/HER-2 antibody    Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 2-5 ug/ml
Flow Cytometry: 5-10 ug/ml
Section Bar
 Testing Data of anti-c-erbB-2/HER-2 antibody    anti-c-erbB-2/HER-2 antibody Testing Data image
Table BarTOPTable Bar
 Molecular Weight    ~185 kDa
Table BarTOPTable Bar

Product References and Citations for anti-c-erbB-2/HER-2 antibody

   Xiao-Feng Le et al (2000) Anti-HER2 Antibody and Heregulin Suppress Growth of HER2-Overexpressing Human Breast Cancer Cells through Different Mechanisms. Clinical Cancer Research Vol. 6, 260-270.
Section Bar
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions