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anti-eIF4A1 antibody :: eIF4A1 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8504039
Western Blot (WB)
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

eIF4A1, Monoclonal Antibody

★Popular Item★
 Also Known As   

eIF4A1 Mouse Monoclonal Antibody

 Product Gene Name   

anti-eIF4A1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602641
 3D Structure    ModBase 3D Structure for P60842
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 Clonality    Monoclonal
 Clone Number    M8
 Species Reactivity    Human, Rat, Mouse
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 Specificity    Antibody can detects endogenous eIF4A1 protein.
 Form/Format    In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Preparation and Storage    Store at-20 degree C for 1 year
 Other Notes    Small volumes of anti-eIF4A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-eIF4A1 antibody

   The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA-this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.
 Applications Tested/Suitable for anti-eIF4A1 antibody   

Western Blot (WB)

 Application Notes for anti-eIF4A1 antibody    WB: 1:1,000-3,000
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 Western Blot (WB) of anti-eIF4A1 antibody    Western blot analysis of 1) 293T, 2) Hela, 3) HepG2, 4) Mouse Brain tissue, 5) Rat Brain tissue with E12-164 diluted at 1:2, 000.
anti-eIF4A1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for eIF4A1. It may not necessarily be applicable to this product.
 NCBI GI #    325197164
 NCBI GeneID    1973
 NCBI Accession #    NP_001191439.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001204510.1 [Other Products]
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 UniProt Primary Accession #    P60842 [Other Products]
 UniProt Secondary Accession #    P04765; Q5U018; Q61516; B2R6L8; D3DTP9; J3QLC4 [Other Products]
 UniProt Related Accession #    P60842 [Other Products]
 Molecular Weight    39,548 Da
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 NCBI Official Full Name    eukaryotic initiation factor 4A-I isoform 2
 NCBI Official Synonym Full Names    eukaryotic translation initiation factor 4A1
 NCBI Official Symbol    EIF4A1 [Similar Products]
 NCBI Official Synonym Symbols   
DDX2A; EIF4A; EIF-4A; eIF4A-I; eIF-4A-I
[Similar Products]
 NCBI Protein Information    eukaryotic initiation factor 4A-I
 UniProt Protein Name    Eukaryotic initiation factor 4A-I
 UniProt Synonym Protein Names   
ATP-dependent RNA helicase eIF4A-1
 Protein Family    Eukaryotic initiation factor
 UniProt Gene Name    EIF4A1 [Similar Products]
 UniProt Synonym Gene Names    DDX2A; EIF4A; eIF-4A-I; eIF4A-I [Similar Products]
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 UniProt Comments for eIF4A1    ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
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 Research Articles on eIF4A1    1. Star-PAP-specific polyadenylation sites usage regulates the expression of the eukaryotic translation initiation factor EIF4A1, the tumor suppressor gene PTEN and the long non-coding RNA NEAT1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-eIF4A1 antibodyPathways associated with anti-eIF4A1 antibody
 Reference Product  PubMed Publications
 EIF4E antibody  >5 publications with eIF4A1 and EIF4E
 EIF4G1 antibody  >2 publications with eIF4A1 and EIF4G1
 EIF4B antibody  >1 publications with eIF4A1 and EIF4B
 PDCD4 antibody  >1 publications with eIF4A1 and PDCD4
 EIF4G2 antibody  >1 publications with eIF4A1 and EIF4G2
 Products by Pathway  Pathway Diagram
 Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway antibodies  Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway Diagram
 Antiviral Mechanism By IFN-stimulated Genes Pathway antibodies  Antiviral Mechanism By IFN-stimulated Genes Pathway Diagram
 Cap-dependent Translation Initiation Pathway antibodies  Cap-dependent Translation Initiation Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Deadenylation Of MRNA Pathway antibodies  Deadenylation Of MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Eukaryotic Translation Initiation Pathway antibodies  Eukaryotic Translation Initiation Pathway Diagram
 GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway antibodies  GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 ISG15 Antiviral Mechanism Pathway antibodies  ISG15 Antiviral Mechanism Pathway Diagram
Diseases associated with anti-eIF4A1 antibodyOrgans/Tissues associated with anti-eIF4A1 antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >5 publications with eIF4A1 and Carcinoma
 Neoplasm Metastasis Antibodies  >3 publications with eIF4A1 and Neoplasm Metastasis
 Liver Diseases Antibodies  >2 publications with eIF4A1 and Liver Diseases
 Skin Diseases Antibodies  >2 publications with eIF4A1 and Skin Diseases
 Lung Neoplasms Antibodies  >2 publications with eIF4A1 and Lung Neoplasms
 Inflammation Antibodies  >1 publications with eIF4A1 and Inflammation
 Nervous System Diseases Antibodies  >1 publications with eIF4A1 and Nervous System Diseases
 Poisoning Antibodies  >1 publications with eIF4A1 and Poisoning
 Drug-Related Side Effects and Adverse Reactions Antibodies  >1 publications with eIF4A1 and Drug-Related Side Effects and Adverse Reactions
 Hyperplasia Antibodies  >1 publications with eIF4A1 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >4 publications with eIF4A1 and Liver
 Blood Antibodies  >2 publications with eIF4A1 and Blood
 Skin Antibodies  >2 publications with eIF4A1 and Skin
 Lung Antibodies  >2 publications with eIF4A1 and Lung
 Ovary Antibodies  >1 publications with eIF4A1 and Ovary
 Lymph Antibodies  >1 publications with eIF4A1 and Lymph
 Cervix Antibodies  >1 publications with eIF4A1 and Cervix
 Pancreas Antibodies  >1 publications with eIF4A1 and Pancreas
 Testis Antibodies  >1 publications with eIF4A1 and Testis
 Larynx Antibodies  >1 publications with eIF4A1 and Larynx
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