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anti-zbtb33 antibody :: Mouse zbtb33 Monoclonal Antibody

Scan QR to view Datasheet Catalog #    MBS850690
Testing Data
Unit / Price
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

zbtb33, Monoclonal Antibody

 Also Known As   

zbtb33 Antibody

 Product Gene Name   

anti-zbtb33 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    300329
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 Clonality    Monoclonal
 Host    Mouse
 Species Reactivity    Xenopus laevis
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 Other Notes    Small volumes of anti-zbtb33 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-zbtb33 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-zbtb33 antibody   


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 Testing Data of anti-zbtb33 antibody    zbtb33 (C-terminus) antibody at 1/2000 dilution + recombinant zbtb33 protein with a GST tag. Predicted band size: 55KDa. Observed band size: 55KDa.
anti-zbtb33 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for zbtb33. It may not necessarily be applicable to this product.
 NCBI GI #    296179376
 NCBI GeneID    10009
 NCBI Accession #    NP_001171671.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001088674 [Other Products]
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 UniProt Secondary Accession #    O00319; Q7Z361; Q8IVP6; Q8N3P0; B2R5U6 [Other Products]
 UniProt Related Accession #    Q86T24 [Other Products]
 Molecular Weight    74,484 Da
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 NCBI Official Full Name    transcriptional regulator Kaiso
 NCBI Official Synonym Full Names    zinc finger and BTB domain containing 33
 NCBI Official Symbol    ZBTB33 [Similar Products]
 NCBI Official Synonym Symbols   
ZNF348; ZNF-kaiso
[Similar Products]
 NCBI Protein Information    transcriptional regulator Kaiso; WUGSC:H_DJ525N14.1; kaiso transcription factor; zinc finger and BTB domain-containing protein 33
 UniProt Protein Name    Transcriptional regulator Kaiso
 UniProt Synonym Protein Names   
Zinc finger and BTB domain-containing protein 33
 Protein Family    Transcriptional regulator
 UniProt Gene Name    ZBTB33 [Similar Products]
 UniProt Synonym Gene Names    KAISO; ZNF348 [Similar Products]
 UniProt Entry Name    KAISO_HUMAN
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 NCBI Summary for zbtb33    This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, May 2010]
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 UniProt Comments for zbtb33    Kaiso: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2.

Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factor

Chromosomal Location of Human Ortholog: Xq23

Cellular Component: nucleoplasm; cytoplasm; nucleolus; plasma membrane; nucleus

Molecular Function: protein binding; methyl-CpG binding; sequence-specific DNA binding; metal ion binding

Biological Process: Wnt receptor signaling pathway; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent
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 Research Articles on zbtb33    1. Nuclear localization of Kaiso promotes the poorly differentiated phenotype and EMT in infiltrating ductal carcinomas.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-zbtb33 antibodyPathways associated with anti-zbtb33 antibody
 Reference Product  PubMed Publications
 CTNND1 antibody  >1 publications with zbtb33 and CTNND1
 Products by Pathway  Pathway Diagram
 Wnt Signaling Pathway And Pluripotency antibodies  Wnt Signaling Pathway And Pluripotency Diagram
Diseases associated with anti-zbtb33 antibodyOrgans/Tissues associated with anti-zbtb33 antibody
 Disease Name  Pubmed Publications
 Mental Disorders Antibodies  >1 publications with zbtb33 and Mental Disorders
 Inflammation Antibodies  >1 publications with zbtb33 and Inflammation
 Neurobehavioral Manifestations Antibodies  >1 publications with zbtb33 and Neurobehavioral Manifestations
 Hyperplasia Antibodies  >1 publications with zbtb33 and Hyperplasia
 Hypertrophy Antibodies  >1 publications with zbtb33 and Hypertrophy
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with zbtb33 and Brain
 Eye Antibodies  >1 publications with zbtb33 and Eye
 Lung Antibodies  >1 publications with zbtb33 and Lung
 Spleen Antibodies  >1 publications with zbtb33 and Spleen
 Muscle Antibodies  >1 publications with zbtb33 and Muscle
 Lymph Node Antibodies  >1 publications with zbtb33 and Lymph Node
 Ear Antibodies  >1 publications with zbtb33 and Ear
 Embryonic Tissue Antibodies  >1 publications with zbtb33 and Embryonic Tissue
 Intestine Antibodies  >1 publications with zbtb33 and Intestine
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