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anti-MtSSB antibody :: Rabbit MtSSB Antibody

Scan QR to view Datasheet Catalog #    MBS854391
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

MtSSB, Antibody

★Popular Item★
 Also Known As   

MtSSB Antibody

 Product Synonym Names    Mt-SSB; MtSSB; PWP1-interacting protein 17; SSB; SSBP; single-stranded DNA-binding protein; mitochondrial
 Product Gene Name   

anti-MtSSB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600439
 3D Structure    ModBase 3D Structure for Q04837
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 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    MtSSB antibody detects endogenous levels of total MtSSB protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human MtSSB.
 Pathway    Transcription
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-MtSSB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-MtSSB antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-MtSSB antibody   

Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)

 Application Notes for anti-MtSSB antibody    WB: 1:500~1:1000, IHC: 1:50~1:100, IF: 1:100~1:500, ELISA: 1:1000
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 Testing Data of anti-MtSSB antibody    anti-MtSSB antibody Testing Data image
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 Testing Data #2 of anti-MtSSB antibody    Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using MtSSB antibody.
Western blot analysis of extracts from HeLa cells and HUVEC cells, using MtSSB antibody.
anti-MtSSB antibody Testing Data #2 image
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 Testing Data #3 of anti-MtSSB antibody    Peptide - +
Immunofluorescence analysis of A549 cells, using MtSSB antibody.
anti-MtSSB antibody Testing Data #3 image
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NCBI/Uniprot data below describe general gene information for MtSSB. It may not necessarily be applicable to this product.
 NCBI GI #    374671775
 NCBI GeneID    6742
 NCBI Accession #    NP_001243439.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001256510.1 [Other Products]
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 UniProt Primary Accession #    Q04837 [Other Products]
 UniProt Related Accession #    Q04837 [Other Products]
 Molecular Weight    17,260 Da
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 NCBI Official Full Name    single-stranded DNA-binding protein, mitochondrial
 NCBI Official Synonym Full Names    single-stranded DNA binding protein 1, mitochondrial
 NCBI Official Symbol    SSBP1 [Similar Products]
 NCBI Official Synonym Symbols   
SSBP; mtSSB; Mt-SSB; SOSS-B1
[Similar Products]
 NCBI Protein Information    single-stranded DNA-binding protein, mitochondrial; PWP1-interacting protein 17
 UniProt Protein Name    Single-stranded DNA-binding protein, mitochondrial
 UniProt Synonym Protein Names   
PWP1-interacting protein 17
 UniProt Gene Name    SSBP1 [Similar Products]
 UniProt Synonym Gene Names    SSBP; Mt-SSB; MtSSB [Similar Products]
 UniProt Entry Name    SSBP_HUMAN
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 NCBI Summary for MtSSB    SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]
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 UniProt Comments for MtSSB    SSBP1: This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication. Associates with mitochondrial DNA.

Protein type: RNA-binding; Mitochondrial

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: mitochondrion; mitochondrial matrix; nucleus

Molecular Function: protein binding; chromatin binding; single-stranded DNA binding

Biological Process: positive regulation of helicase activity; mitochondrion organization and biogenesis; organelle organization and biogenesis; DNA replication
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Product References and Citations for anti-MtSSB antibody

   Tiranti V., Gene 126:219-225(1993).
Matsuoka S., Science 316:1160-1166(2007).
Yang C., Nat. Struct. Biol. 4:153-157(1997).
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 Research Articles on MtSSB    1. In response to the DNA damage response, INTS3-hSSB1-INTS6 complex relocates to the DNA damage sites.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-MtSSB antibodyPathways associated with anti-MtSSB antibody
 Reference Product  PubMed Publications
 SSBP2 antibody  >6 publications with MtSSB and SSBP2
 INTS3 antibody  >5 publications with MtSSB and INTS3
 C9orf80 antibody  >5 publications with MtSSB and C9orf80
 RBBP8 antibody  >1 publications with MtSSB and RBBP8
 Products by Pathway  Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
 DNA Replication Pathway antibodies  DNA Replication Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Homologous Recombination Pathway antibodies  Homologous Recombination Pathway Diagram
 Mismatch Repair Pathway antibodies  Mismatch Repair Pathway Diagram
 Mismatch Repair Pathway antibodies  Mismatch Repair Pathway Diagram
 Mitochondrial Biogenesis Pathway antibodies  Mitochondrial Biogenesis Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 Transcriptional Activation Of Mitochondrial Biogenesis Pathway antibodies  Transcriptional Activation Of Mitochondrial Biogenesis Pathway Diagram
Diseases associated with anti-MtSSB antibodyOrgans/Tissues associated with anti-MtSSB antibody
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >3 publications with MtSSB and Liver Diseases
 Liver Neoplasms Antibodies  >2 publications with MtSSB and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >2 publications with MtSSB and Carcinoma, Hepatocellular
 Kidney Diseases Antibodies  >2 publications with MtSSB and Kidney Diseases
 Ovarian Neoplasms Antibodies  >1 publications with MtSSB and Ovarian Neoplasms
 Neoplasm Metastasis Antibodies  >1 publications with MtSSB and Neoplasm Metastasis
 Skin Diseases Antibodies  >1 publications with MtSSB and Skin Diseases
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >3 publications with MtSSB and Kidney
 Liver Antibodies  >3 publications with MtSSB and Liver
 Brain Antibodies  >3 publications with MtSSB and Brain
 Thyroid Antibodies  >2 publications with MtSSB and Thyroid
 Connective Tissue Antibodies  >1 publications with MtSSB and Connective Tissue
 Stomach Antibodies  >1 publications with MtSSB and Stomach
 Blood Antibodies  >1 publications with MtSSB and Blood
 Embryonic Tissue Antibodies  >1 publications with MtSSB and Embryonic Tissue
 Placenta Antibodies  >1 publications with MtSSB and Placenta
 Bone Antibodies  >1 publications with MtSSB and Bone
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