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anti-NDUFA4 antibody :: Rabbit NDUFA4 Antibody

Scan QR to view Datasheet Catalog #    MBS002942
Western blot
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NDUFA4, Antibody

 Also Known As   

Rabbit NDUFA4 Antibody

 Product Gene Name   

anti-NDUFA4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 7; NC_000007.13 (10971580..10979813, complement). Location: 7p21.3
 OMIM    603833
 3D Structure    ModBase 3D Structure for O00483
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 Host    Rabbit
 Species Reactivity    Human, mouse, rat
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 Specificity    NDUFA4 Antibody detects endogenous levels of total NDUFA4
 Purity/Purification    Immunogen affinity purified
 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Preparation and Storage    Store at -20 degree C. Stable for 12 months from date of receipt.
 Other Notes    Small volumes of anti-NDUFA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-NDUFA4 antibody

   Background/Introduction: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
 Applications Tested/Suitable for anti-NDUFA4 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-NDUFA4 antibody    WB 1:500-1:2000
Optimal dilutions/concentrations should be determined by the end user.
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 Western blot of anti-NDUFA4 antibody    Western blot analysis of NDUFA4 expression in HepG2 cells
anti-NDUFA4 antibody Western blot image
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NCBI/Uniprot data below describe general gene information for NDUFA4. It may not necessarily be applicable to this product.
 NCBI GI #    4505357
 NCBI GeneID    4697
 NCBI Accession #    NP_002480.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002489.3 [Other Products]
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 UniProt Primary Accession #    O00483 [Other Products]
 UniProt Secondary Accession #    Q6FHN5; A4D109 [Other Products]
 UniProt Related Accession #    O00483 [Other Products]
 Molecular Weight    9,370 Da
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 NCBI Official Full Name    NADH dehydrogenase
 NCBI Official Synonym Full Names    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
 NCBI Official Symbol    NDUFA4 [Similar Products]
 NCBI Official Synonym Symbols   
MLRQ; CI-9k; CI-MLRQ
[Similar Products]
 NCBI Protein Information    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; complex I-MLRQ; Complex I 9kDa subunit; NADH-ubiquinone oxidoreductase MLRQ subunit
 UniProt Protein Name    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4
 UniProt Synonym Protein Names   
Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit
 Protein Family    Cytochrome c oxidase
 UniProt Gene Name    NDUFA4 [Similar Products]
 UniProt Synonym Gene Names    CI-MLRQ [Similar Products]
 UniProt Entry Name    NDUA4_HUMAN
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 NCBI Summary for NDUFA4    The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]
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 UniProt Comments for NDUFA4    NDUFA4: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA4 subunit family.

Protein type: Oxidoreductase; Mitochondrial; Energy Metabolism - oxidative phosphorylation; EC 1.6.5.3; EC 1.6.99.3

Chromosomal Location of Human Ortholog: 7p21.3

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex IV; mitochondrial respiratory chain complex I

Molecular Function: protein binding; cytochrome-c oxidase activity; NADH dehydrogenase (ubiquinone) activity; protein complex binding

Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone
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 Research Articles on NDUFA4    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-NDUFA4 antibodyDiseases associated with anti-NDUFA4 antibody
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies  NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Oxidative Phosphorylation Pathway antibodies  Oxidative Phosphorylation Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with NDUFA4 and Nervous System Diseases
 Death Antibodies  >2 publications with NDUFA4 and Death
 Cognition Disorders Antibodies  >1 publications with NDUFA4 and Cognition Disorders
 Mitochondrial Diseases Antibodies  >1 publications with NDUFA4 and Mitochondrial Diseases
 Drug Toxicity Antibodies  >1 publications with NDUFA4 and Drug Toxicity
Organs/Tissues associated with anti-NDUFA4 antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with NDUFA4 and Kidney
 Muscle Antibodies  >1 publications with NDUFA4 and Muscle
 Liver Antibodies  >1 publications with NDUFA4 and Liver
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