NP_076924.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,621 Da
NCBI Official Full Name
neurogenin-2
NCBI Official Synonym Full Names
neurogenin 2
NCBI Official Synonym Symbols
NGN2; Atoh4; ngn-2; Math4A; bHLHa8 [Similar Products]
NCBI Protein Information
neurogenin-2
UniProt Protein Name
Neurogenin-2
UniProt Synonym Protein Names
Class A basic helix-loop-helix protein 8; bHLHa8; Protein atonal homolog 4
UniProt Synonym Gene Names
NCBI Summary for NEUROG2
This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012]
UniProt Comments for NEUROG2
neurogenin 2: a master regulatory transcription factor involved in neuronal differentiation. Controls the balance between progenitor maintenance and differentiation in the response to increasing cell cycle length during development. Its multi-site phosphorylation at CDK sites regulates the stability of its binding to promoters of downstream transcriptional targets, resulting in the regulation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').
Protein type: Transcription factor
Chromosomal Location of Human Ortholog: 4q25
Biological Process: positive regulation of transcription factor activity
Research Articles on NEUROG2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-NEUROG2 antibody
Diseases associated with anti-NEUROG2 antibody
Organs/Tissues associated with anti-NEUROG2 antibody
|