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anti-NFATC2 antibody :: Rabbit NFATC2 Antibody

Scan QR to view Datasheet Catalog #    MBS8500592
Testing Data
Unit / Price
0.1 mL  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NFATC2, Antibody

★Popular Item★
 Also Known As   

NFATC2 Antibody

 Product Synonym Names    NFAT1; NFATP
 Product Gene Name   

anti-NFATC2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600490
 3D Structure    ModBase 3D Structure for Q13469
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 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity purification
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 Immunogen    A synthetic peptide of human NFATC2
 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-NFATC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-NFATC2 antibody

   This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.
 Product Categories/Family for anti-NFATC2 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-NFATC2 antibody   

Western Blot (WB)

 Application Notes for anti-NFATC2 antibody    WB: 1:500-1:1000
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 Testing Data of anti-NFATC2 antibody    Western blot analysis of extracts of mouse fetal brain cellline, using NFATC2antibody.
anti-NFATC2 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for NFATC2. It may not necessarily be applicable to this product.
 NCBI GI #    209862843
 NCBI GeneID    4773
 NCBI Accession #    NP_001129493.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001136021.2 [Other Products]
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 UniProt Primary Accession #    Q13469 [Other Products]
 UniProt Secondary Accession #    Q13468; Q5TFW7; Q5TFW8; Q9NPX6; Q9NQH3; Q9UJR2; B5B2N8; B5B2N9; B5B2P0; B5B2P2; B5B2P3 [Other Products]
 UniProt Related Accession #    Q13469 [Other Products]
 Molecular Weight    98kDa
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 NCBI Official Full Name    nuclear factor of activated T-cells, cytoplasmic 2 isoform D
 NCBI Official Synonym Full Names    nuclear factor of activated T cells 2
 NCBI Official Symbol    NFATC2 [Similar Products]
 NCBI Official Synonym Symbols   
NFAT1; NFATP
[Similar Products]
 NCBI Protein Information    nuclear factor of activated T-cells, cytoplasmic 2
 UniProt Protein Name    Nuclear factor of activated T-cells, cytoplasmic 2
 UniProt Synonym Protein Names   
NFAT pre-existing subunit; NF-ATp; T-cell transcription factor NFAT1
 Protein Family    NFATC2-interacting protein
 UniProt Gene Name    NFATC2 [Similar Products]
 UniProt Synonym Gene Names    NFAT1; NFATP; NF-ATc2; NFATc2; NF-ATp [Similar Products]
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 NCBI Summary for NFATC2    This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
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 UniProt Comments for NFATC2    Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.
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 Research Articles on NFATC2    1. NFATc2 and Sp1 are co-localized in cell nuclei and physically interact at the NFAT target sequence termed NFAT-responsive promotor construct. Sp1 increases the functional activity of its binding partner NFATc2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-NFATC2 antibodyPathways associated with anti-NFATC2 antibody
 Reference Product  PubMed Publications
 JUN antibody  >49 publications with NFATC2 and JUN
 FOS antibody  >21 publications with NFATC2 and FOS
 FOXP3 antibody  >20 publications with NFATC2 and FOXP3
 IL2 antibody  >6 publications with NFATC2 and IL2
 EGR1 antibody  >5 publications with NFATC2 and EGR1
 IL4 antibody  >4 publications with NFATC2 and IL4
 IRF4 antibody  >3 publications with NFATC2 and IRF4
 MAPK8 antibody  >2 publications with NFATC2 and MAPK8
 MEF2D antibody  >1 publications with NFATC2 and MEF2D
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 C-type Lectin Receptors (CLRs) Pathway antibodies  C-type Lectin Receptors (CLRs) Pathway Diagram
 CLEC7A (Dectin-1) Induces NFAT Activation Pathway antibodies  CLEC7A (Dectin-1) Induces NFAT Activation Pathway Diagram
 CLEC7A (Dectin-1) Signaling Pathway antibodies  CLEC7A (Dectin-1) Signaling Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Signaling In The CD4+ TCR Pathway antibodies  Calcium Signaling In The CD4+ TCR Pathway Diagram
Diseases associated with anti-NFATC2 antibodyOrgans/Tissues associated with anti-NFATC2 antibody
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >49 publications with NFATC2 and Immune System Diseases
 Necrosis Antibodies  >29 publications with NFATC2 and Necrosis
 Inflammation Antibodies  >29 publications with NFATC2 and Inflammation
 Disease Models, Animal Antibodies  >23 publications with NFATC2 and Disease Models, Animal
 Nervous System Diseases Antibodies  >18 publications with NFATC2 and Nervous System Diseases
 Lung Diseases Antibodies  >15 publications with NFATC2 and Lung Diseases
 Hypertrophy Antibodies  >15 publications with NFATC2 and Hypertrophy
 Brain Diseases Antibodies  >12 publications with NFATC2 and Brain Diseases
 Hypertension Antibodies  >11 publications with NFATC2 and Hypertension
 Cardiovascular Diseases Antibodies  >10 publications with NFATC2 and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >211 publications with NFATC2 and Blood
 Lung Antibodies  >19 publications with NFATC2 and Lung
 Heart Antibodies  >18 publications with NFATC2 and Heart
 Spleen Antibodies  >17 publications with NFATC2 and Spleen
 Brain Antibodies  >16 publications with NFATC2 and Brain
 Skin Antibodies  >13 publications with NFATC2 and Skin
 Lymph Node Antibodies  >11 publications with NFATC2 and Lymph Node
 Lymph Antibodies  >10 publications with NFATC2 and Lymph
 Thymus Antibodies  >8 publications with NFATC2 and Thymus
 Embryonic Tissue Antibodies  >4 publications with NFATC2 and Embryonic Tissue
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