Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow NMDAR1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Cytomegalovirus pp52 (UL44) (CMV pp52) Recombinant Protein
 • CCL4L1 Recombinant Protein
 • ARG1 Antibody
 • A Disintegrin And Metalloproteinase With Thrombospondin 1 (A... Recombinant Protein
 • CD247 Antibody
 • p21 Antibody
 • b-Amyloid Peptide, 28aa Antibody
 • Anti-Neutrophil Elastase Antibody (ANEA) ELISA Kit
 • hydrocephalus inducing homolog (mouse) (HYDIN) ELISA Kit
 • Escherichia coli protein (E.coli P) ELISA Kit
 • Fibroblast Growth Factor 7 (FGF7) ELISA Kit
 • Maelstrom Blocking Peptide
 • AP2A2 Antibody
 • sCD14 ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-NMDAR1 antibody :: Rabbit NMDAR1 (Phospho-Ser890) Antibody

Scan QR to view Datasheet Catalog #    MBS002870 anti-NMDAR1 antibody
Unit / Price
0.05 mL  /  $270 +1 FREE 8GB USB
0.1 mL  /  $445 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

NMDAR1 (Phospho-Ser890), Antibody

 Also Known As   

Rabbit NMDAR1 (Phospho-Ser890) Antibody

 Product Gene Name   

anti-NMDAR1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Chromosome Location    Chromosome: 9; NC_000009.11 (140033609..140063214). Location: 9q34.3
 OMIM    138249
 3D Structure    ModBase 3D Structure for Q05586
Section Bar
 Host    Rabbit
 Species Reactivity    Human, mouse, rat
Section Bar
 Form/Format    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
 Concentration    1 mg/ml (lot specific)
Section Bar
Section Bar
 Other Notes    Small volumes of anti-NMDAR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Applications Tested/Suitable for anti-NMDAR1 antibody   

Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA (EIA)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for NMDAR1. It may not necessarily be applicable to this product.
 NCBI GI #    11496971
 NCBI GeneID    2902
 NCBI Accession #    NP_000823.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_000832.6 [Other Products]
Section Bar
 UniProt Primary Accession #    Q05586 [Other Products]
 UniProt Secondary Accession #    P35437; Q12867; Q12868; Q5VSF3; Q5VSF4; Q5VSF5; Q5VSF6; Q5VSF7; A6NLK7; A6NLR1; C9K0X1 [Other Products]
 UniProt Related Accession #    Q05586 [Other Products]
 Molecular Weight    105,373 Da
Table BarTOPTable Bar
 NCBI Official Full Name    glutamate receptor ionotropic, NMDA 1 isoform NR1-1
 NCBI Official Synonym Full Names    glutamate receptor, ionotropic, N-methyl D-aspartate 1
 NCBI Official Symbol    GRIN1 [Similar Products]
 NCBI Official Synonym Symbols   
NR1; MRD8; GluN1; NMDA1; NMDAR1
[Similar Products]
 NCBI Protein Information    glutamate receptor ionotropic, NMDA 1; NMD-R1; glutamate [NMDA] receptor subunit zeta 1; glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; N-methyl-D-aspartate receptor channel, subunit zeta-1
 UniProt Protein Name    Glutamate receptor ionotropic, NMDA 1
 UniProt Synonym Protein Names   
Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1
 Protein Family    Glutamate [NMDA] receptor
 UniProt Gene Name    GRIN1 [Similar Products]
 UniProt Synonym Gene Names    NMDAR1; GluN1; NMD-R1 [Similar Products]
 UniProt Entry Name    NMDZ1_HUMAN
Section Bar
 NCBI Summary for NMDAR1    The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for NMDAR1    NMDAR1: a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission. Three alternatively-spliced isoforms have been described.

Protein type: Membrane protein, integral; Channel, ligand-gated; Channel, calcium; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: neuron projection; cell surface; integral to plasma membrane; endoplasmic reticulum; postsynaptic density; dendrite; dendritic spine; terminal button; excitatory synapse; N-methyl-D-aspartate selective glutamate receptor complex; postsynaptic membrane; synaptic vesicle; plasma membrane; synapse; cell junction

Molecular Function: voltage-gated cation channel activity; neurotransmitter binding; glutamate receptor binding; calcium channel activity; calcium ion binding; calmodulin binding; protein binding; enzyme binding; glutamate binding; extracellular-glutamate-gated ion channel activity; protein heterodimerization activity; N-methyl-D-aspartate selective glutamate receptor activity; glycine binding

Biological Process: regulation of long-term neuronal synaptic plasticity; axon guidance; male mating behavior; prepulse inhibition; adult locomotory behavior; positive regulation of apoptosis; regulation of dendrite morphogenesis; rhythmic process; response to morphine; sensory perception of pain; regulation of axonogenesis; calcium ion homeostasis; synaptic transmission; regulation of respiratory gaseous exchange; conditioned taste aversion; ephrin receptor signaling pathway; visual learning; negative regulation of neuron apoptosis; cation transport; protein tetramerization; synaptic transmission, glutamatergic; response to amphetamine; social behavior; respiratory gaseous exchange; pons maturation; cellular calcium ion homeostasis; regulation of membrane potential; response to ethanol; propylene metabolic process; olfactory learning; suckling behavior; long-term memory; regulation of synaptogenesis; ionotropic glutamate receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cerebral cortex development; regulation of excitatory postsynaptic membrane potential; response to calcium ion

Disease: Mental Retardation, Autosomal Dominant 8
Table BarTOPTable Bar
 Research Articles on NMDAR1    1. Adult NR1-deficient transgenic mice show multiple abnormal behaviors including reduced social interactions, locomotor hyperactivity, self-injury, deficits in prepulse inhibition and sensory hypersensitivity, among others.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-NMDAR1 antibodyPathways associated with anti-NMDAR1 antibody
 Reference Product  PubMed Publications
 GRIN2B antibody  >20 publications with NMDAR1 and GRIN2B
 GRIN2A antibody  >16 publications with NMDAR1 and GRIN2A
 GRIN2D antibody  >5 publications with NMDAR1 and GRIN2D
 SP3 antibody  >2 publications with NMDAR1 and SP3
 GRIN3A antibody  >2 publications with NMDAR1 and GRIN3A
 DRD1 antibody  >2 publications with NMDAR1 and DRD1
 SYNGAP1 antibody  >1 publications with NMDAR1 and SYNGAP1
 PLCG1 antibody  >1 publications with NMDAR1 and PLCG1
 DLG4 antibody  >1 publications with NMDAR1 and DLG4
 CAMK2A antibody  >1 publications with NMDAR1 and CAMK2A
 Products by Pathway  Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimers Disease Pathway antibodies  Alzheimers Disease Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amphetamine Addiction Pathway antibodies  Amphetamine Addiction Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
Diseases associated with anti-NMDAR1 antibodyOrgans/Tissues associated with anti-NMDAR1 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >16 publications with NMDAR1 and Nervous System Diseases
 Brain Diseases Antibodies  >9 publications with NMDAR1 and Brain Diseases
 Disease Models, Animal Antibodies  >7 publications with NMDAR1 and Disease Models, Animal
 Memory Disorders Antibodies  >5 publications with NMDAR1 and Memory Disorders
 Movement Disorders Antibodies  >4 publications with NMDAR1 and Movement Disorders
 Nerve Degeneration Antibodies  >4 publications with NMDAR1 and Nerve Degeneration
 Learning Disorders Antibodies  >4 publications with NMDAR1 and Learning Disorders
 Neoplasms Antibodies  >4 publications with NMDAR1 and Neoplasms
 Pain Antibodies  >4 publications with NMDAR1 and Pain
 Seizures Antibodies  >3 publications with NMDAR1 and Seizures
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >48 publications with NMDAR1 and Brain
 Nerve Antibodies  >45 publications with NMDAR1 and Nerve
 Eye Antibodies  >2 publications with NMDAR1 and Eye
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions