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anti-PCAD antibody :: Rabbit P-Cadherin Antibody

Scan QR to view Datasheet Catalog #    MBS8501498
Western Blot (WB)
Unit / Price
0.1 mL  /  $310 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

P-Cadherin (PCAD), Antibody

 Also Known As   

P-Cadherin Antibody

 Product Synonym Names    DHP; HJMD
 Product Gene Name   

anti-PCAD antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    114021
 3D Structure    ModBase 3D Structure for P22223
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 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Affinity purification
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 Immunogen    Recombinant protein of human CDH3
 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at-20 degree C or-80 degree C. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-PCAD antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-PCAD antibody

   This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congentialhypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008]
 Product Categories/Family for anti-PCAD antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-PCAD antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-PCAD antibody    WB: 1:500-1:2000
IHC: 1:50-1:200
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 Western Blot (WB) of anti-PCAD antibody    Western blot analysis of extracts of A431 cellslines, using CDH3 antibody.
anti-PCAD antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for PCAD. It may not necessarily be applicable to this product.
 NCBI GI #    953953841
 NCBI GeneID    1001
 NCBI Accession #    NP_001304124.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001317195.1 [Other Products]
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 UniProt Primary Accession #    P22223 [Other Products]
 UniProt Secondary Accession #    Q05DI6; B2R6F4 [Other Products]
 UniProt Related Accession #    P22223 [Other Products]
 Molecular Weight    91kDa
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 NCBI Official Full Name    cadherin-3 isoform 2
 NCBI Official Synonym Full Names    cadherin 3
 NCBI Official Symbol    CDH3 [Similar Products]
 NCBI Official Synonym Symbols   
CDHP; HJMD; PCAD
[Similar Products]
 NCBI Protein Information    cadherin-3
 UniProt Protein Name    Cadherin-3
 UniProt Synonym Protein Names   
Placental cadherin; P-cadherin
 Protein Family    3-oxoadipate enol-lactonase
 UniProt Gene Name    CDH3 [Similar Products]
 UniProt Synonym Gene Names    CDHP; P-cadherin [Similar Products]
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 NCBI Summary for PCAD    This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015]
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 UniProt Comments for PCAD    Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
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 Research Articles on PCAD    1. the evaluation of P-cadherin expression in lymph node metastases is an important predictor of disease outcome in breast cancer axillary lymph node metastases
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-PCAD antibodyPathways associated with anti-PCAD antibody
 Reference Product  PubMed Publications
 CDH1 antibody  >23 publications with PCAD and CDH1
 CTNNB1 antibody  >4 publications with PCAD and CTNNB1
 CDH11 antibody  >3 publications with PCAD and CDH11
 CDH5 antibody  >2 publications with PCAD and CDH5
 CDH13 antibody  >2 publications with PCAD and CDH13
 CDH8 antibody  >1 publications with PCAD and CDH8
 Products by Pathway  Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
Diseases associated with anti-PCAD antibodyOrgans/Tissues associated with anti-PCAD antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >15 publications with PCAD and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >6 publications with PCAD and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >5 publications with PCAD and Lung Neoplasms
 Lung Diseases Antibodies  >5 publications with PCAD and Lung Diseases
 Neoplasm Metastasis Antibodies  >5 publications with PCAD and Neoplasm Metastasis
 Ectodermal dysplasia, ectrodactyly, and macular dystrophy Antibodies  >5 publications with PCAD and Ectodermal dysplasia, ectrodactyly, and macular dystrophy
 Neoplasms, Experimental Antibodies  >4 publications with PCAD and Neoplasms, Experimental
 Inflammation Antibodies  >4 publications with PCAD and Inflammation
 Chromosome Aberrations Antibodies  >4 publications with PCAD and Chromosome Aberrations
 Precancerous Conditions Antibodies  >3 publications with PCAD and Precancerous Conditions
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >9 publications with PCAD and Eye
 Skin Antibodies  >8 publications with PCAD and Skin
 Lung Antibodies  >6 publications with PCAD and Lung
 Liver Antibodies  >6 publications with PCAD and Liver
 Intestine Antibodies  >6 publications with PCAD and Intestine
 Blood Antibodies  >5 publications with PCAD and Blood
 Stomach Antibodies  >4 publications with PCAD and Stomach
 Embryonic Tissue Antibodies  >4 publications with PCAD and Embryonic Tissue
 Prostate Antibodies  >3 publications with PCAD and Prostate
 Thyroid Antibodies  >3 publications with PCAD and Thyroid
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