BAA09306
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
118,809 Da
NCBI Official Full Name
phosphodiesterase 3B
NCBI Official Synonym Full Names
phosphodiesterase 3B
NCBI Protein Information
cGMP-inhibited 3',5'-cyclic phosphodiesterase B
UniProt Protein Name
cGMP-inhibited 3',5'-cyclic phosphodiesterase B
UniProt Synonym Protein Names
CGIPDE1; CGIP1; Cyclic GMP-inhibited phosphodiesterase B; CGI-PDE B
UniProt Synonym Gene Names
UniProt Entry Name
PDE3B_HUMAN
UniProt Comments for PDE3B
PDE3B: a cGMP-inhibited phosphodiesterase 1 involved in fat metabolism. Inhibition of PDE3B can augment PDE4 inhibitor-induced apoptosis in some patients with chronic lymphocytic leukemia.
Protein type: Membrane protein, multi-pass; EC 3.1.4.17; Phosphodiesterase; Membrane protein, integral; Nucleotide Metabolism - purine
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: cytosol; endoplasmic reticulum; Golgi apparatus; integral to membrane; membrane
Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; cGMP-inhibited cyclic-nucleotide phosphodiesterase activity; metal ion binding; protein binding; protein kinase B binding
Biological Process: angiogenesis; cAMP catabolic process; cellular response to insulin stimulus; negative regulation of angiogenesis; negative regulation of cell adhesion; negative regulation of cell adhesion mediated by integrin; negative regulation of lipid catabolic process; signal transduction
Research Articles on PDE3B
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Pathways associated with anti-PDE3B antibody
Diseases associated with anti-PDE3B antibody
Organs/Tissues associated with anti-PDE3B antibody
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