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anti-PE2R2 antibody :: Rabbit PE2R2 Antibody

Scan QR to view Datasheet Catalog #    MBS856009
Testing Data
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PE2R2, Antibody

 Also Known As   

PE2R2 Antibody

 Product Synonym Names    Prostaglandin E2 receptor EP2 subtype; Prostanoid EP2 receptor; PGE receptor; EP2 subtype; PTGER2
 Product Gene Name   

anti-PE2R2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    176804
 3D Structure    ModBase 3D Structure for P43116
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 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    PE2R2 antibody detects endogenous levels of total PE2R2 protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human PE2R2.
 Pathway    GPCR
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-PE2R2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-PE2R2 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-PE2R2 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-PE2R2 antibody    WB: 1:500~1:1000, ELISA: 1:1000
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 Testing Data of anti-PE2R2 antibody    Western blot analysis of extracts from mouse liver cells, using PE2R2 antibody.
anti-PE2R2 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for PE2R2. It may not necessarily be applicable to this product.
 NCBI GI #    31881630
 NCBI GeneID    5732
 NCBI Accession #    NP_000947.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_000956.3 [Other Products]
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 UniProt Primary Accession #    P43116 [Other Products]
 UniProt Secondary Accession #    Q52LG8; D3DSC0 [Other Products]
 UniProt Related Accession #    P43116 [Other Products]
 Molecular Weight    39,761 Da
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 NCBI Official Full Name    prostaglandin E2 receptor EP2 subtype
 NCBI Official Synonym Full Names    prostaglandin E receptor 2 (subtype EP2), 53kDa
 NCBI Official Symbol    PTGER2 [Similar Products]
 NCBI Official Synonym Symbols   
EP2
[Similar Products]
 NCBI Protein Information    prostaglandin E2 receptor EP2 subtype; prostanoid EP2 receptor; PGE receptor EP2 subtype; PGE2 receptor EP2 subtype; prostaglandin E receptor 2 (subtype EP2), 53kD
 UniProt Protein Name    Prostaglandin E2 receptor EP2 subtype
 UniProt Synonym Protein Names   
Prostanoid EP2 receptor
 UniProt Gene Name    PTGER2 [Similar Products]
 UniProt Synonym Gene Names    PGE receptor EP2 subtype; PGE2 receptor EP2 subtype [Similar Products]
 UniProt Entry Name    PE2R2_HUMAN
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 NCBI Summary for PE2R2    This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009]
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 UniProt Comments for PE2R2    PTGER2: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 14q22

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: prostaglandin E receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; response to lipopolysaccharide; G-protein signaling, adenylate cyclase activating pathway; regulation of cell proliferation

Disease: Asthma, Nasal Polyps, And Aspirin Intolerance
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Product References and Citations for anti-PE2R2 antibody

   Regan J.W., Mol. Pharmacol. 46:213-220(1994).
Smock S.L., Gene 237:393-402(1999).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
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 Research Articles on PE2R2    1. EP2/cAMP/protein kinase A pathway mediates the stimulatory effect of PGEs on angiogenesis essential for tissue injury healing via the induction of CREB activity and VEGF expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to PE2R2 Antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS003298  Rabbit PE2R2 Antibody  MBS856009  PE2R2 Antibody
 MBS8515580  PE2R2 Antibody  MBS5300943  PE2R2 antibody
Products associated with anti-PE2R2 antibodyPathways associated with anti-PE2R2 antibody
 Reference Product  PubMed Publications
 PTGER4 antibody  >207 publications with PE2R2 and PTGER4
 PTH antibody  >4 publications with PE2R2 and PTH
 ADRB2 antibody  >2 publications with PE2R2 and ADRB2
 POMC antibody  >1 publications with PE2R2 and POMC
 CRH antibody  >1 publications with PE2R2 and CRH
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Eicosanoid Ligand-binding Receptors Pathway antibodies  Eicosanoid Ligand-binding Receptors Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Inflammatory Mediator Regulation Of TRP Channels Pathway antibodies  Inflammatory Mediator Regulation Of TRP Channels Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with anti-PE2R2 antibodyOrgans/Tissues associated with anti-PE2R2 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >67 publications with PE2R2 and Inflammation
 Necrosis Antibodies  >38 publications with PE2R2 and Necrosis
 Nervous System Diseases Antibodies  >23 publications with PE2R2 and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >22 publications with PE2R2 and Cardiovascular Diseases
 Immune System Diseases Antibodies  >21 publications with PE2R2 and Immune System Diseases
 Lung Neoplasms Antibodies  >12 publications with PE2R2 and Lung Neoplasms
 Adenocarcinoma Antibodies  >11 publications with PE2R2 and Adenocarcinoma
 Kidney Diseases Antibodies  >7 publications with PE2R2 and Kidney Diseases
 Neoplasms, Experimental Antibodies  >6 publications with PE2R2 and Neoplasms, Experimental
 Uterine Diseases Antibodies  >6 publications with PE2R2 and Uterine Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >108 publications with PE2R2 and Blood
 Lung Antibodies  >46 publications with PE2R2 and Lung
 Uterus Antibodies  >39 publications with PE2R2 and Uterus
 Kidney Antibodies  >30 publications with PE2R2 and Kidney
 Eye Antibodies  >21 publications with PE2R2 and Eye
 Bone Marrow Antibodies  >15 publications with PE2R2 and Bone Marrow
 Connective Tissue Antibodies  >9 publications with PE2R2 and Connective Tissue
 Liver Antibodies  >9 publications with PE2R2 and Liver
 Ascites Antibodies  >2 publications with PE2R2 and Ascites
 Adipose Tissue Antibodies  >1 publications with PE2R2 and Adipose Tissue
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