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anti-HSPE1 antibody :: Rabbit anti-Human 10 kDa heat shock protein Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS715748
Western Blot
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

10 kDa heat shock protein (HSPE1), Polyclonal Antibody

 Also Known As   

Rabbit anti-human 10 kDa heat shock protein, mitochondrial polyclonal Antibody

 Product Gene Name   

anti-HSPE1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600141
 3D Structure    ModBase 3D Structure for P61604
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human 10 kDa heat shock protein, mitochondrial protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-21375 / sc-21373 / sc-20958
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-HSPE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-HSPE1 antibody

   Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
 Applications Tested/Suitable for anti-HSPE1 antibody   

ELISA (EIA)

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 Western Blot of anti-HSPE1 antibody    anti-HSPE1 antibody Western Blot (WB) image
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NCBI/Uniprot data below describe general gene information for HSPE1. It may not necessarily be applicable to this product.
 NCBI GI #    4504523
 NCBI GeneID    3336
 NCBI Accession #    NP_002148.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002157.2 [Other Products]
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 UniProt Primary Accession #    P61604 [Other Products]
 UniProt Secondary Accession #    O95421; Q04984; Q53X54; Q9UDH0 [Other Products]
 UniProt Related Accession #    P61604 [Other Products]
 Molecular Weight    10,932 Da [Similar Products]
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 NCBI Official Full Name    10 kDa heat shock protein, mitochondrial
 NCBI Official Synonym Full Names    heat shock protein family E (Hsp10) member 1
 NCBI Official Symbol    HSPE1 [Similar Products]
 NCBI Official Synonym Symbols   
EPF; CPN10; GROES; HSP10
[Similar Products]
 NCBI Protein Information    10 kDa heat shock protein, mitochondrial
 UniProt Protein Name    10 kDa heat shock protein, mitochondrial
 UniProt Synonym Protein Names   
10 kDa chaperonin; Chaperonin 10; CPN10; Early-pregnancy factor; EPF
 Protein Family    10 kDa heat shock protein
 UniProt Gene Name    HSPE1 [Similar Products]
 UniProt Synonym Gene Names    Hsp10; CPN10; EPF [Similar Products]
 UniProt Entry Name    CH10_HUMAN
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 NCBI Summary for HSPE1    This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.[provided by RefSeq, Feb 2011]
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 UniProt Comments for HSPE1    HSPE1: Eukaryotic CPN10 homolog which is essential for mitochondrial protein biogenesis, together with CPN60. Binds to CPN60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. Belongs to the GroES chaperonin family.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 2q33.1

Cellular Component: membrane; mitochondrial matrix; mitochondrion

Molecular Function: ATP binding; chaperone binding; protein binding; unfolded protein binding

Biological Process: caspase activation; osteoblast differentiation; protein folding; response to unfolded protein
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 Research Articles on HSPE1    1. Hsp10 has a role in nuclear localization and lung cells response to cigarette smoke
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HSPE1 antibodyDiseases associated with anti-HSPE1 antibody
 Reference Product  PubMed Publications
 HSPD1 antibody  >10 publications with HSPE1 and HSPD1
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2 publications with HSPE1 and Carcinoma
 Kidney Neoplasms Antibodies  >1 publications with HSPE1 and Kidney Neoplasms
 Adenocarcinoma Antibodies  >1 publications with HSPE1 and Adenocarcinoma
 Breast Neoplasms Antibodies  >1 publications with HSPE1 and Breast Neoplasms
 Liver Diseases Antibodies  >1 publications with HSPE1 and Liver Diseases
 Edema Antibodies  >1 publications with HSPE1 and Edema
 Kidney Diseases Antibodies  >1 publications with HSPE1 and Kidney Diseases
 Hyperplasia Antibodies  >1 publications with HSPE1 and Hyperplasia
Organs/Tissues associated with anti-HSPE1 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with HSPE1 and Blood
 Embryonic Tissue Antibodies  >2 publications with HSPE1 and Embryonic Tissue
 Connective Tissue Antibodies  >1 publications with HSPE1 and Connective Tissue
 Vascular Antibodies  >1 publications with HSPE1 and Vascular
 Skin Antibodies  >1 publications with HSPE1 and Skin
 Kidney Antibodies  >1 publications with HSPE1 and Kidney
 Testis Antibodies  >1 publications with HSPE1 and Testis
 Lung Antibodies  >1 publications with HSPE1 and Lung
 Liver Antibodies  >1 publications with HSPE1 and Liver
 Brain Antibodies  >1 publications with HSPE1 and Brain
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