NP_061223.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
14-3-3 protein beta/alpha
NCBI Official Synonym Full Names
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
NCBI Protein Information
14-3-3 protein beta/alpha
UniProt Protein Name
14-3-3 protein beta/alpha
UniProt Synonym Protein Names
Protein kinase C inhibitor protein 1; KCIP-1
UniProt Synonym Gene Names
UniProt Comments for Ywhab
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activation of MAP kinases via AKAP13.
Product References and Citations for anti-Ywhab antibody
1. Carninci P., Kasukawa T., et al. Science 309:1559-1563(2005). 2. Sacksteder C.A., Qian W.-J., et al. Biochemistry 45:8009-8022(2006). 3. Fu, H., et al. 14-3-3 proteins: structure, function, and regulation. Ann. Rev. Pharmacol. Toxicol. 40: 617-47 (2000).
Research Articles on Ywhab
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Pathways associated with anti-Ywhab antibody
Diseases associated with anti-Ywhab antibody
Organs/Tissues associated with anti-Ywhab antibody
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