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anti-YWHAQ antibody :: Goat 14-3-3 tau/YWHAQ Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420856
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3 tau/YWHAQ, Polyclonal Antibody

 Also Known As   

Goat anti-14-3-3 tau/YWHAQ Antibody

 Product Synonym Names    YWHAQ; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; 14-3-3; 1C5; HS1; 14-3-3 protein T-cell; 14-3-3 protein theta; protein tau; tyrosine 3/tryptophan 5 -monooxygenase activation protein, th; YWHAQ antibody; 14-3-3 protein tau antibody; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein; theta polypeptide antibody; 14-3-3 antibody; 1C5 antibody; HS1 antibody; 14-3-3 protein T-cell antibody; 14-3-3 protein theta antibody; protein tau antibody; tyrosine 3/tryptophan 5 -monooxygenase activation protein; theta polypeptide antibody; 14-3-3 tau / YWHAQ
 Product Gene Name   

anti-YWHAQ antibody

[Similar Products]
 Product Synonym Gene Name    14-3-3 tau [Similar Products]
 Antibody/Peptide Pairs    14-3-3 tau / YWHAQ peptide (MBS425780) is used for blocking the activity of 14-3-3 tau/YWHAQ antibody (MBS420856)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    DDRKQTIDNS Q
 OMIM    609009
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-DDRKQTIDNSQ, from the internal region of the protein sequence according to NP_006817.1.
 Epitope    Internal region
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-YWHAQ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-YWHAQ antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-YWHAQ antibody    Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Approx 28kDa band observed in Human Brain (Hippocampus) lysates (calculated MW of 27.8kDa according to NP_006817.1). Recommended concentration: 0. 03-0.1ug/ml.
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 Western Blot (WB) of anti-YWHAQ antibody    (0. 03ug/ml) staining of Human Brain (Hippocampus) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
anti-YWHAQ antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for YWHAQ. It may not necessarily be applicable to this product.
 NCBI GI #    5803227
 NCBI GeneID    10971
 NCBI Accession #    NP_006817.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006826.3 [Other Products]
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 UniProt Secondary Accession #    Q567U5; Q5TZU8; Q9UP48; D6W4Z5 [Other Products]
 UniProt Related Accession #    P27348 [Other Products]
 Molecular Weight    27,764 Da
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 NCBI Official Full Name    14-3-3 protein theta
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
 NCBI Official Symbol    YWHAQ [Similar Products]
 NCBI Official Synonym Symbols   
1C5; HS1; 14-3-3
[Similar Products]
 NCBI Protein Information    14-3-3 protein theta
 UniProt Protein Name    14-3-3 protein theta
 UniProt Synonym Protein Names   
14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
 Protein Family    14-3-3 protein
 UniProt Gene Name    YWHAQ [Similar Products]
 UniProt Entry Name    1433T_HUMAN
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 NCBI Summary for YWHAQ    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for YWHAQ    14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: cytoplasm; cytoplasmic vesicle membrane; cytosol; focal adhesion; membrane; mitochondrion; protein complex

Molecular Function: protein binding; protein C-terminus binding; protein domain specific binding; protein N-terminus binding

Biological Process: negative regulation of transcription, DNA-dependent; protein targeting; small GTPase mediated signal transduction; substantia nigra development
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 Research Articles on YWHAQ    1. Study shows that 14-3-3 zeta/delta is important in the extracellular vesicles mediated induction of colon malignant phenotype, suggesting its role as a potential target for therapeutic interventions.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-YWHAQ antibodyPathways associated with anti-YWHAQ antibody
 Reference Product  PubMed Publications
 BAD antibody  >1 publications with YWHAQ and BAD
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
Diseases associated with anti-YWHAQ antibodyOrgans/Tissues associated with anti-YWHAQ antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >2 publications with YWHAQ and Carcinoma
 Neoplasm Metastasis Antibodies  >1 publications with YWHAQ and Neoplasm Metastasis
 Adenocarcinoma Antibodies  >1 publications with YWHAQ and Adenocarcinoma
 Disease Models, Animal Antibodies  >1 publications with YWHAQ and Disease Models, Animal
 Breast Neoplasms Antibodies  >1 publications with YWHAQ and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >5 publications with YWHAQ and Brain
 Muscle Antibodies  >4 publications with YWHAQ and Muscle
 Nerve Antibodies  >3 publications with YWHAQ and Nerve
 Heart Antibodies  >2 publications with YWHAQ and Heart
 Prostate Antibodies  >2 publications with YWHAQ and Prostate
 Blood Antibodies  >2 publications with YWHAQ and Blood
 Embryonic Tissue Antibodies  >2 publications with YWHAQ and Embryonic Tissue
 Ovary Antibodies  >1 publications with YWHAQ and Ovary
 Liver Antibodies  >1 publications with YWHAQ and Liver
 Kidney Antibodies  >1 publications with YWHAQ and Kidney
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