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anti-YWHAQ antibody :: Rabbit 14-3-3, tau Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS623624 anti-YWHAQ antibody
Unit / Price
0.1 mL  /  $675 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3, tau (YWHAQ), Polyclonal Antibody

 Also Known As   

14-3-3, tau (14-3-3 Protein tau, 14-3-3 Protein T cell, 14-3-3 Protein theta, 14-3-3 theta, HS1, KCIP1, Protein HS1, Protein Kinase C Inhibitor Protein 1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein theta Polypeptide, Tyr3/trp5

 Product Synonym Names    Anti -14-3-3, tau (14-3-3 Protein tau, 14-3-3 Protein T cell, 14-3-3 Protein theta, 14-3-3 theta, HS1, KCIP1, Protein HS1, Protein Kinase C Inhibitor Protein 1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase Activation Protein theta Polypeptide, Tyr3/trp5
 Product Gene Name   

anti-YWHAQ antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 2; NC_000002.11 (9724096..9771184, complement). Location: 2p25.1
 OMIM    609009
 3D Structure    ModBase 3D Structure for P27348
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Bovine, Chicken, Human, Mouse, Rabbit, Rat, Sheep
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 Specificity    Recognizes sheep 1433 at ~30 kD. Species Crossreactivity: human, bovine, chicken, rat, mouse and rabbit.
 Purity/Purification    Serum
Serum
 Form/Format    Supplied as a liquid, 0.09% sodium azide.
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 Immunogen    Synthetic peptide, Ac.MEKTELIQKAC, corresponding to acetylated Nterminal sequence of sheep 1433 tau/theta.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-YWHAQ antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-YWHAQ antibody    Antibodies; Abs to 14-3-3
 Applications Tested/Suitable for anti-YWHAQ antibody   

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-YWHAQ antibody    Suitable for use in ELISA, Immunohistochemistry (paraffin), and Western Blot.
Dilution: Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment prior to staining of paraffin sections.
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NCBI/Uniprot data below describe general gene information for YWHAQ. It may not necessarily be applicable to this product.
 NCBI GI #    5803227
 NCBI GeneID    10971
 NCBI Accession #    NP_006817.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006826.3 [Other Products]
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 UniProt Primary Accession #    P27348 [Other Products]
 UniProt Secondary Accession #    Q567U5; Q5TZU8; Q9UP48; D6W4Z5 [Other Products]
 UniProt Related Accession #    P27348 [Other Products]
 Molecular Weight    27,764 Da [Similar Products]
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 NCBI Official Full Name    14-3-3 protein theta
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
 NCBI Official Symbol    YWHAQ [Similar Products]
 NCBI Official Synonym Symbols   
1C5; HS1; 14-3-3
[Similar Products]
 NCBI Protein Information    14-3-3 protein theta; 14-3-3 protein tau; 14-3-3 protein T-cell
 UniProt Protein Name    14-3-3 protein theta
 UniProt Synonym Protein Names   
14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
 Protein Family    14-3-3 protein
 UniProt Gene Name    YWHAQ [Similar Products]
 UniProt Entry Name    1433T_HUMAN
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 NCBI Summary for YWHAQ    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for YWHAQ    14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: focal adhesion; cytoplasmic vesicle membrane; membrane; cytoplasm; cytosol

Molecular Function: protein domain specific binding; protein binding; protein N-terminus binding

Biological Process: substantia nigra development; apoptosis; small GTPase mediated signal transduction; negative regulation of transcription, DNA-dependent; protein targeting
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 Research Articles on YWHAQ    1. 14-3-3 negatively regulates the RGC downstream of the PI3-kinase/Akt signaling pathway
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-YWHAQ antibodyPathways associated with anti-YWHAQ antibody
 Reference Product  PubMed Publications
 BAD antibody  >1 publications with YWHAQ and BAD
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Class I PI3K Signaling Events Mediated By Akt Pathway antibodies  Class I PI3K Signaling Events Mediated By Akt Pathway Diagram
 Epstein-Barr Virus Infection Pathway antibodies  Epstein-Barr Virus Infection Pathway Diagram
Diseases associated with anti-YWHAQ antibodyOrgans/Tissues associated with anti-YWHAQ antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with YWHAQ and Neoplasms
 Adenocarcinoma Antibodies  >1 publications with YWHAQ and Adenocarcinoma
 Breast Neoplasms Antibodies  >1 publications with YWHAQ and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >4 publications with YWHAQ and Muscle
 Nerve Antibodies  >3 publications with YWHAQ and Nerve
 Brain Antibodies  >3 publications with YWHAQ and Brain
 Heart Antibodies  >2 publications with YWHAQ and Heart
 Embryonic Tissue Antibodies  >2 publications with YWHAQ and Embryonic Tissue
 Liver Antibodies  >1 publications with YWHAQ and Liver
 Kidney Antibodies  >1 publications with YWHAQ and Kidney
 Prostate Antibodies  >1 publications with YWHAQ and Prostate
 Blood Antibodies  >1 publications with YWHAQ and Blood
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