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anti-14-3-3 antibody :: Rabbit anti-Human 14-3-3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS668093
Western Blot (WB)
Unit / Price
0.025 mg  /  $155 +1 FREE 8GB USB
0.1 mg  /  $250 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

14-3-3, Polyclonal Antibody

 Also Known As   

14-3-3 Polyclonal Antibody

 Product Gene Name   

anti-14-3-3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609009
 3D Structure    ModBase 3D Structure for P27348
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Purified (Liquid)
 Concentration    0.5mg/ml, 200l (lot specific)
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 Antigen    14-3-3
 Immunogen    A partial recombinant 14-3-3 protein (amino acids 20-225) was used as the immunogen for this antibody.
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 Preparation and Storage    Store antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles. Expire 1 year from date of purchase.
 Other Notes    Small volumes of anti-14-3-3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-14-3-3 antibody    Apoptosis
 Applications Tested/Suitable for anti-14-3-3 antibody   

Western Blot (WB)

 Application Notes for anti-14-3-3 antibody    Western Blot: 2-4 g/ml
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 Western Blot (WB) of anti-14-3-3 antibody    Expression analysis of 14-3-3.Anti-14-3-3 antibody (11-1023) was used at 4 g/ml on (1) MCF-7 and (2)A431 lysates.
anti-14-3-3 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for 14-3-3. It may not necessarily be applicable to this product.
 NCBI GI #    5803227
 NCBI GeneID    10971
 NCBI Accession #    NP_006817.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006826.3 [Other Products]
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 UniProt Primary Accession #    P27348 [Other Products]
 UniProt Secondary Accession #    Q567U5; Q5TZU8; Q9UP48; D6W4Z5 [Other Products]
 UniProt Related Accession #    P27348 [Other Products]
 Molecular Weight    27,764 Da
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 NCBI Official Full Name    14-3-3 protein theta
 NCBI Official Synonym Full Names    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
 NCBI Official Symbol    YWHAQ [Similar Products]
 NCBI Official Synonym Symbols   
1C5; HS1; 14-3-3
[Similar Products]
 NCBI Protein Information    14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
 UniProt Protein Name    14-3-3 protein theta
 UniProt Synonym Protein Names   
14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
 Protein Family    14-3-3 protein
 UniProt Gene Name    YWHAQ [Similar Products]
 UniProt Entry Name    1433T_HUMAN
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 NCBI Summary for 14-3-3    This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
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 UniProt Comments for 14-3-3    14-3-3 theta: a protein of the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. A multifunctional regulator of the cell signaling processes. Associates with c-BCR and BCR-Abl.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 2p25.1

Cellular Component: cytoplasmic vesicle membrane; focal adhesion; membrane; cytoplasm; cytosol

Molecular Function: protein domain specific binding; protein binding; protein N-terminus binding

Biological Process: substantia nigra development; apoptosis; small GTPase mediated signal transduction; negative regulation of transcription, DNA-dependent; protein targeting
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 Research Articles on 14-3-3    1. 14-3-3epsilon is involved in the regulation of cell cycle control, apoptosis, adhesion, carbohydrate metabolism, and nucleic acid metabolism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-14-3-3 antibodyPathways associated with anti-14-3-3 antibody
 Reference Product  PubMed Publications
 BAD antibody  >1 publications with 14-3-3 and BAD
 Products by Pathway  Pathway Diagram
 Activation Of BAD And Translocation To Mitochondria Pathway antibodies  Activation Of BAD And Translocation To Mitochondria Pathway Diagram
 Activation Of BH3-only Proteins Pathway antibodies  Activation Of BH3-only Proteins Pathway Diagram
 Alpha6-Beta4 Integrin Signaling Pathway antibodies  Alpha6-Beta4 Integrin Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
Diseases associated with anti-14-3-3 antibodyOrgans/Tissues associated with anti-14-3-3 antibody
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >1 publications with 14-3-3 and Adenocarcinoma
 Immunoproliferative Disorders Antibodies  >1 publications with 14-3-3 and Immunoproliferative Disorders
 Breast Neoplasms Antibodies  >1 publications with 14-3-3 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >4 publications with 14-3-3 and Muscle
 Brain Antibodies  >4 publications with 14-3-3 and Brain
 Nerve Antibodies  >3 publications with 14-3-3 and Nerve
 Heart Antibodies  >2 publications with 14-3-3 and Heart
 Prostate Antibodies  >2 publications with 14-3-3 and Prostate
 Blood Antibodies  >2 publications with 14-3-3 and Blood
 Embryonic Tissue Antibodies  >2 publications with 14-3-3 and Embryonic Tissue
 Kidney Antibodies  >1 publications with 14-3-3 and Kidney
 Placenta Antibodies  >1 publications with 14-3-3 and Placenta
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