Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow OGDH rightarrow Polyclonal OGDH  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • VCAM1 Peptide
 • RAB11 family interacting protein 2 (class I) (RAB11FIP2) Antibody
 • Interleukin 8 (IL-8) (IL8) Antibody
 • Filamin A (FLNA) Antibody
 • Growth Hormone (hGH) (GH1) Antibody
 • gastrokine 1 (GKN1) ELISA Kit
 • Transthyretin (TTR) ELISA Kit
 • NMDAR2B Antibody
 • NUP198 ELISA Kit
 • Diphtheria Toxin-Toxoid Antibody
 • SLC28A2 Antibody
 • AP-2 complex subunit mu (AP2M1) Antibody
 • Hepatitis C Virus (HCV) Nucleocapsid NS3-NS4-NS5, Recombinan... Recombinant Protein
 • 4-Hydroxynonenal (HNE) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-OGDH antibody :: Rabbit anti-Human 2-oxoglutarate dehydrogenase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1489446 anti-OGDH antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

2-oxoglutarate dehydrogenase (OGDH), Polyclonal Antibody

 Also Known As   

Rabbit anti-human 2-oxoglutarate dehydrogenase, mitochondrial polyclonal Antibody, Biotin conjugated

 Product Synonym Names    2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase
 Product Gene Name   

anti-OGDH antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    613022
 3D Structure    ModBase 3D Structure for Q02218
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation Purified
Section Bar
 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Biotin
 Immunogen    Recombinant human 2-oxoglutarate dehydrogenase, mitochondrial protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-49589 / sc-49590 / sc-49591 / sc-67238
Section Bar
 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-OGDH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-OGDH antibody

   The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
 Applications Tested/Suitable for anti-OGDH antibody   

ELISA (EIA)

Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for OGDH. It may not necessarily be applicable to this product.
 NCBI GI #    51873038
 NCBI GeneID    4967
 NCBI Accession #    NP_001003941.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001003941.2 [Other Products]
Section Bar
 UniProt Primary Accession #    Q02218 [Other Products]
 UniProt Secondary Accession #    Q96DD3; Q9UDX0; B4E2U9; D3DVL0; E9PBM1 [Other Products]
 UniProt Related Accession #    Q02218 [Other Products]
 Molecular Weight    48,180 Da
Table BarTOPTable Bar
 NCBI Official Full Name    2-oxoglutarate dehydrogenase, mitochondrial isoform 2
 NCBI Official Synonym Full Names    oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
 NCBI Official Symbol    OGDH [Similar Products]
 NCBI Official Synonym Symbols   
E1k; OGDC; AKGDH
[Similar Products]
 NCBI Protein Information    2-oxoglutarate dehydrogenase, mitochondrial
 UniProt Protein Name    2-oxoglutarate dehydrogenase, mitochondrial
 UniProt Synonym Protein Names   
2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; Alpha-ketoglutarate dehydrogenase
 Protein Family    2-oxoglutarate dehydrogenase
 UniProt Gene Name    OGDH [Similar Products]
 UniProt Synonym Gene Names    OGDC-E1 [Similar Products]
 UniProt Entry Name    ODO1_HUMAN
Section Bar
 NCBI Summary for OGDH    This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Sep 2009]
Section Bar
 UniProt Comments for OGDH    OGDH: The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). Belongs to the alpha-ketoglutarate dehydrogenase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - lysine degradation; Oxidoreductase; Mitochondrial; Amino Acid Metabolism - tryptophan; EC 1.2.4.2; Carbohydrate Metabolism - citrate (TCA) cycle

Chromosomal Location of Human Ortholog: 7p14-p13

Cellular Component: cytosol; mitochondrial matrix; mitochondrial membrane; mitochondrion; oxoglutarate dehydrogenase complex

Molecular Function: chaperone binding; heat shock protein binding; metal ion binding; oxoglutarate dehydrogenase (succinyl-transferring) activity; thiamin pyrophosphate binding

Biological Process: 2-oxoglutarate metabolic process; cellular metabolic process; cerebellar cortex development; generation of precursor metabolites and energy; glycolysis; glyoxylate metabolic process; hippocampus development; lysine catabolic process; NADH metabolic process; pyramidal neuron development; striatum development; succinyl-CoA metabolic process; tangential migration from the subventricular zone to the olfactory bulb; thalamus development; tricarboxylic acid cycle

Disease: Alpha-ketoglutarate Dehydrogenase Deficiency
Table BarTOPTable Bar
 Research Articles on OGDH    1. ATP consumption is demonstrated in respiration-impaired isolated mice and in situ neuronal mitochondria from transgenic mice with dihydrolipoyl succinyltransferase deficiency.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-OGDH antibodyPathways associated with anti-OGDH antibody
 Reference Product  PubMed Publications
 DLST antibody  >1 publications with OGDH and DLST
 Products by Pathway  Pathway Diagram
 2-oxoglutarate Decarboxylation To Succinyl-CoA Pathway antibodies  2-oxoglutarate Decarboxylation To Succinyl-CoA Pathway Diagram
 2-oxoglutarate Decarboxylation To Succinyl-CoA Pathway antibodies  2-oxoglutarate Decarboxylation To Succinyl-CoA Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram
 Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway antibodies  Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
 Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway antibodies  Citrate Cycle, Second Carbon Oxidation, 2-oxoglutarate => Oxaloacetate Pathway Diagram
Diseases associated with anti-OGDH antibodyOrgans/Tissues associated with anti-OGDH antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >4 publications with OGDH and Nervous System Diseases
 Heart Diseases Antibodies  >3 publications with OGDH and Heart Diseases
 Cardiovascular Diseases Antibodies  >3 publications with OGDH and Cardiovascular Diseases
 Brain Diseases Antibodies  >2 publications with OGDH and Brain Diseases
 Disease Models, Animal Antibodies  >2 publications with OGDH and Disease Models, Animal
 Liver Diseases Antibodies  >2 publications with OGDH and Liver Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with OGDH and Cell Transformation, Neoplastic
 Liver Cirrhosis Antibodies  >1 publications with OGDH and Liver Cirrhosis
 Fatty Liver Antibodies  >1 publications with OGDH and Fatty Liver
 Hyperplasia Antibodies  >1 publications with OGDH and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >16 publications with OGDH and Muscle
 Heart Antibodies  >9 publications with OGDH and Heart
 Liver Antibodies  >8 publications with OGDH and Liver
 Brain Antibodies  >6 publications with OGDH and Brain
 Blood Antibodies  >5 publications with OGDH and Blood
 Kidney Antibodies  >3 publications with OGDH and Kidney
 Pancreas Antibodies  >3 publications with OGDH and Pancreas
 Adipose Tissue Antibodies  >3 publications with OGDH and Adipose Tissue
 Vascular Antibodies  >3 publications with OGDH and Vascular
 Bone Antibodies  >2 publications with OGDH and Bone
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions