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anti-DAP3 antibody :: Rabbit anti-Human 28S ribosomal protein S29 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1493778
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

28S ribosomal protein S29 (DAP3), Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit anti-human 28S ribosomal protein S29, mitochondrial polyclonal Antibody(DAP3)

 Product Synonym Names    MRP-S29; S29mt; Death-associated protein 3; DAP-3; Ionizing radiation resistance conferring protein; DAP3; MRPS29
 Product Gene Name   

anti-DAP3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602074
 3D Structure    ModBase 3D Structure for P51398
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
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 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Conjugate    Non-conjugated
 Immunogen    Recombinant human 28S ribosomal protein S29, mitochondrial protein (159-398aa)
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-14099
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-DAP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-DAP3 antibody

   Involved in mediating interferon-gamma-induced cell death.
 Applications Tested/Suitable for anti-DAP3 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-DAP3 antibody    Recommended dilution: WB:1:500-2000
IHC:1:20-1:200
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 Western Blot (WB) of anti-DAP3 antibody    All lanes: 28S ribosomal protein S29, mitochondrial antibody at 10ug/ml
Lane 1:Hela whole cell lysate
Lane 2:293T whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 46,42 kDa
Observed band size: 46 kDa

anti-DAP3 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-DAP3 antibody    Immunohistochemistry of paraffin-embedded human breast cancer using MBS1493778 at dilution 1:100
anti-DAP3 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for DAP3. It may not necessarily be applicable to this product.
 NCBI GI #    315434212
 NCBI GeneID    7818
 NCBI Accession #    NP_001186778.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199849.1 [Other Products]
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 UniProt Primary Accession #    P51398 [Other Products]
 UniProt Secondary Accession #    Q13044; Q68CT7; Q96Q20; B4DP59; B4DY62; E7EM60 [Other Products]
 UniProt Related Accession #    P51398 [Other Products]
 Molecular Weight    41,673 Da
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 NCBI Official Full Name    28S ribosomal protein S29, mitochondrial isoform 1
 NCBI Official Synonym Full Names    death associated protein 3
 NCBI Official Symbol    DAP3 [Similar Products]
 NCBI Official Synonym Symbols   
DAP-3; MRPS29; MRP-S29; bMRP-10
[Similar Products]
 NCBI Protein Information    28S ribosomal protein S29, mitochondrial
 UniProt Protein Name    28S ribosomal protein S29, mitochondrial
 UniProt Synonym Protein Names   
Death-associated protein 3; DAP-3; Ionizing radiation resistance conferring protein
 Protein Family    28S ribosomal protein
 UniProt Gene Name    DAP3 [Similar Products]
 UniProt Synonym Gene Names    MRPS29; MRP-S29; S29mt; DAP-3 [Similar Products]
 UniProt Entry Name    RT29_HUMAN
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 NCBI Summary for DAP3    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]
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 UniProt Comments for DAP3    DAP3: Involved in mediating interferon-gamma-induced cell death. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Nuclear receptor co-regulator; Mitochondrial

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: mitochondrial inner membrane; mitochondrial small ribosomal subunit; mitochondrion; nucleoplasm

Molecular Function: protein binding; structural constituent of ribosome

Biological Process: apoptotic mitochondrial changes; mitochondrial translation; organelle organization and biogenesis
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 Research Articles on DAP3    1. DAP3 plays important roles in mitochondrial function and dynamics
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-DAP3 antibodyPathways associated with anti-DAP3 antibody
 Reference Product  PubMed Publications
 FADD antibody  >8 publications with DAP3 and FADD
 TNFRSF10A antibody  >3 publications with DAP3 and TNFRSF10A
 Products by Pathway  Pathway Diagram
 Mitochondrial Translation Pathway antibodies  Mitochondrial Translation Pathway Diagram
 Mitochondrial Translation Elongation Pathway antibodies  Mitochondrial Translation Elongation Pathway Diagram
 Mitochondrial Translation Initiation Pathway antibodies  Mitochondrial Translation Initiation Pathway Diagram
 Mitochondrial Translation Termination Pathway antibodies  Mitochondrial Translation Termination Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 TRAIL Signaling Pathway antibodies  TRAIL Signaling Pathway Diagram
Diseases associated with anti-DAP3 antibodyOrgans/Tissues associated with anti-DAP3 antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >9 publications with DAP3 and Necrosis
 Breast Neoplasms Antibodies  >2 publications with DAP3 and Breast Neoplasms
 Embryo Loss Antibodies  >1 publications with DAP3 and Embryo Loss
 Cardiovascular Diseases Antibodies  >1 publications with DAP3 and Cardiovascular Diseases
 Atrophy Antibodies  >1 publications with DAP3 and Atrophy
 Nervous System Diseases Antibodies  >1 publications with DAP3 and Nervous System Diseases
 Disease Models, Animal Antibodies  >1 publications with DAP3 and Disease Models, Animal
 Learning Disorders Antibodies  >1 publications with DAP3 and Learning Disorders
 Inflammation Antibodies  >1 publications with DAP3 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >7 publications with DAP3 and Blood
 Thymus Antibodies  >2 publications with DAP3 and Thymus
 Vascular Antibodies  >2 publications with DAP3 and Vascular
 Lung Antibodies  >2 publications with DAP3 and Lung
 Stomach Antibodies  >1 publications with DAP3 and Stomach
 Bone Antibodies  >1 publications with DAP3 and Bone
 Heart Antibodies  >1 publications with DAP3 and Heart
 Lymph Node Antibodies  >1 publications with DAP3 and Lymph Node
 Liver Antibodies  >1 publications with DAP3 and Liver
 Connective Tissue Antibodies  >1 publications with DAP3 and Connective Tissue
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