NP_064621.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
39S ribosomal protein L1, mitochondrial
NCBI Official Synonym Full Names
mitochondrial ribosomal protein L1
NCBI Protein Information
39S ribosomal protein L1, mitochondrial
UniProt Protein Name
39S ribosomal protein L1, mitochondrial
UniProt Synonym Gene Names
UniProt Entry Name
RM01_HUMAN
NCBI Summary for MRPL1
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
UniProt Comments for MRPL1
MRPL1: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq, Jul 2008]
Protein type: Mitochondrial; RNA-binding
Chromosomal Location of Human Ortholog: 4q21.1
Cellular Component: large ribosomal subunit; mitochondrial inner membrane
Molecular Function: protein binding; structural constituent of ribosome
Biological Process: mitochondrial translation; organelle organization and biogenesis
Research Articles on MRPL1
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Pathways associated with anti-MRPL1 antibody
Diseases associated with anti-MRPL1 antibody
Organs/Tissues associated with anti-MRPL1 antibody
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