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anti-MRPL19 antibody :: Rabbit anti-Human 39S ribosomal protein L19, mitochondrial Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7001166
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

39S ribosomal protein L19, mitochondrial (MRPL19), Polyclonal Antibody

 Also Known As   

Rabbit anti-human 39S ribosomal protein L19, mitochondrial polyclonal Antibody

 Product Synonym Names    39S ribosomal protein L15; mitochondrial MRPL19 KIAA0104; MRPL15
 Product Gene Name   

anti-MRPL19 antibody

[Similar Products]
 Product Synonym Gene Name    MRPL19 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611832
 3D Structure    ModBase 3D Structure for P49406
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Caprylic Acid Ammonium Sulfate Precipitation purified
 Form/Format    Liquid
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 Immunogen    Recombinant human 39S ribosomal protein L19, mitochondrial protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-MRPL19 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-MRPL19 antibody

   Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
 Product Categories/Family for anti-MRPL19 antibody    Epigenetics and Nuclear Signaling
 Applications Tested/Suitable for anti-MRPL19 antibody   

ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)

 Application Notes for anti-MRPL19 antibody    Recommended dilution: WB:1:500-2000, IHC:1:20-1:200
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 Western Blot (WB) of anti-MRPL19 antibody    Western Blot (WB): All lanes: 39S ribosomal protein L19, mitochondrial antibody at 2ug/ml Lane 1: MCF-7 whole cell lysate Lane 2: mouse liver tissue Secondary Goat polyclonal to Rabbit IgG at 1/10000 dilution Predicted band size:34kDa Observed band size:34kDaImmunohistochemistry
anti-MRPL19 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-MRPL19 antibody    Immunohistochemistry of paraffin-embedded human placenta dilution of 1:50
anti-MRPL19 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for MRPL19. It may not necessarily be applicable to this product.
 NCBI GI #    94557305
 NCBI GeneID    9801
 NCBI Accession #    NP_055578.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_014763.3 [Other Products]
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 UniProt Primary Accession #    P49406 [Other Products]
 UniProt Secondary Accession #    Q53TX9; Q96Q52 [Other Products]
 UniProt Related Accession #    P49406 [Other Products]
 Molecular Weight    33,535 Da [Similar Products]
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 NCBI Official Full Name    39S ribosomal protein L19, mitochondrial
 NCBI Official Synonym Full Names    mitochondrial ribosomal protein L19
 NCBI Official Symbol    MRPL19 [Similar Products]
 NCBI Official Synonym Symbols   
RLX1; L19mt; MRPL15; RPML15; MRP-L15; MRP-L19
[Similar Products]
 NCBI Protein Information    39S ribosomal protein L19, mitochondrial
 UniProt Protein Name    39S ribosomal protein L19, mitochondrial
 UniProt Synonym Protein Names   
39S ribosomal protein L15, mitochondrial; L15mt; MRP-L15
 Protein Family    39S ribosomal protein
 UniProt Gene Name    MRPL19 [Similar Products]
 UniProt Synonym Gene Names    KIAA0104; MRPL15; L19mt; MRP-L19; L15mt; MRP-L15 [Similar Products]
 UniProt Entry Name    RM19_HUMAN
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 NCBI Summary for MRPL19    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
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 UniProt Comments for MRPL19    MRPL19: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Protein type: Ribosomal; Mitochondrial; Translation

Chromosomal Location of Human Ortholog: 2p11.1-q11.2

Cellular Component: mitochondrial inner membrane; mitochondrial large ribosomal subunit; nuclear membrane; nucleus

Molecular Function: structural constituent of ribosome

Biological Process: mitochondrial translation; organelle organization and biogenesis
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 Research Articles on MRPL19    1. MRPL19 was initially implicated in dyslexia through family-based studies.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-MRPL19 antibodyDiseases associated with anti-MRPL19 antibody
 Products by Pathway  Pathway Diagram
 Cytoplasmic Ribosomal Proteins Pathway antibodies  Cytoplasmic Ribosomal Proteins Pathway Diagram
 Mitochondrial Translation Pathway antibodies  Mitochondrial Translation Pathway Diagram
 Mitochondrial Translation Elongation Pathway antibodies  Mitochondrial Translation Elongation Pathway Diagram
 Mitochondrial Translation Initiation Pathway antibodies  Mitochondrial Translation Initiation Pathway Diagram
 Mitochondrial Translation Termination Pathway antibodies  Mitochondrial Translation Termination Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 Ribosome Pathway antibodies  Ribosome Pathway Diagram
 Ribosome Pathway antibodies  Ribosome Pathway Diagram
 Disease Name  Pubmed Publications
 Learning Disorders Antibodies  >14 publications with MRPL19 and Learning Disorders
 Breast Neoplasms Antibodies  >5 publications with MRPL19 and Breast Neoplasms
 Cognition Disorders Antibodies  >2 publications with MRPL19 and Cognition Disorders
 Neoplasms, Experimental Antibodies  >2 publications with MRPL19 and Neoplasms, Experimental
 Abnormalities, Multiple Antibodies  >1 publications with MRPL19 and Abnormalities, Multiple
 Inflammation Antibodies  >1 publications with MRPL19 and Inflammation
Organs/Tissues associated with anti-MRPL19 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with MRPL19 and Brain
 Nerve Antibodies  >6 publications with MRPL19 and Nerve
 Blood Antibodies  >2 publications with MRPL19 and Blood
 Parathyroid Antibodies  >1 publications with MRPL19 and Parathyroid
 Muscle Antibodies  >1 publications with MRPL19 and Muscle
 Pancreas Antibodies  >1 publications with MRPL19 and Pancreas
 Uterus Antibodies  >1 publications with MRPL19 and Uterus
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