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anti-4-1BB antibody :: Rabbit anti-Human 4-1BBL Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS695575 anti-4-1BB antibody
Unit / Price
0.025 mg  /  $185 +1 FREE 8GB USB
0.05 mg  /  $215 +1 FREE 8GB USB
1 mg  /  $2,780 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

4-1BBL, Polyclonal Antibody

 Also Known As   

Biotinylated Anti-h4-1BBL

 Product Synonym Names    Biotinylated Anti-Human 4-1BB Ligand
 Product Gene Name   

anti-4-1BB antibody

[Similar Products]
 Matching Pairs    Capture Antibody: 4-1BB (MBS695160)
Detection Antibody: 4-1BB Ligand (MBS695575)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606182
 3D Structure    ModBase 3D Structure for P41273
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Biotin
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 Immunogen    Recombinant Human 4-1BB Ligand
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 Preparation and Storage    At -20 degree C
 Other Notes    Small volumes of anti-4-1BB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-4-1BB antibody

   Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant h4-1BBL (human 4-1BBLigand). Anti-Human 4-1BBL specific antibody was purified by affinity chromatography and then biotinylated.
 Applications Tested/Suitable for anti-4-1BB antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-4-1BB antibody    Direct Detection: To detect h4-1BBL by direct ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant h4-1BBL.

Sandwich ELISA: To detect h4-1BBL by sandwich ELISA (using 100 mul/well antibody solution) a concentration of 0.25 - 1.0 mug/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with Polyclonal Anti-Human 4-1BBL as a capture antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant h4-1BBL.

Western Blot: To detect h4-1BBL by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 mug/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant h4-1BBL is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
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NCBI/Uniprot data below describe general gene information for 4-1BB. It may not necessarily be applicable to this product.
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 UniProt Primary Accession #    P41273 [Other Products]
 UniProt Secondary Accession #    Q2M3S2 [Other Products]
 Molecular Weight    26,625 Da
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 UniProt Protein Name    Tumor necrosis factor ligand superfamily member 9
 UniProt Synonym Protein Names   
4-1BB ligand; 4-1BBL
 UniProt Gene Name    TNFSF9 [Similar Products]
 UniProt Synonym Gene Names    4-1BBL [Similar Products]
 UniProt Entry Name    TNFL9_HUMAN
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 UniProt Comments for 4-1BB    TNFL9: Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. Belongs to the tumor necrosis factor family.

Protein type: Cell cycle regulation; Cytokine; Membrane protein, integral; Apoptosis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular space; integral to membrane; plasma membrane

Molecular Function: cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: cell proliferation; positive regulation of interferon-gamma production; positive regulation of cytotoxic T cell differentiation; cell-cell signaling; apoptosis; positive regulation of interleukin-12 production; positive regulation of interleukin-6 production; immune response; myeloid dendritic cell differentiation; signal transduction; positive regulation of activated T cell proliferation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-4-1BB antibodyDiseases associated with anti-4-1BB antibody
 Reference Product  PubMed Publications
 TNFRSF9 antibody  >76 publications with 4-1BB and TNFRSF9
 CD40 antibody  >17 publications with 4-1BB and CD40
 TNFSF4 antibody  >14 publications with 4-1BB and TNFSF4
 CD70 antibody  >9 publications with 4-1BB and CD70
 ICAM1 antibody  >5 publications with 4-1BB and ICAM1
 TRAF2 antibody  >2 publications with 4-1BB and TRAF2
 TRAF1 antibody  >1 publications with 4-1BB and TRAF1
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >129 publications with 4-1BB and Necrosis
 Disease Models, Animal Antibodies  >18 publications with 4-1BB and Disease Models, Animal
 Inflammation Antibodies  >16 publications with 4-1BB and Inflammation
 Gastrointestinal Diseases Antibodies  >14 publications with 4-1BB and Gastrointestinal Diseases
 Neoplasms, Experimental Antibodies  >14 publications with 4-1BB and Neoplasms, Experimental
 Liver Diseases Antibodies  >11 publications with 4-1BB and Liver Diseases
 Liver Neoplasms Antibodies  >10 publications with 4-1BB and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >5 publications with 4-1BB and Carcinoma, Hepatocellular
 Lung Neoplasms Antibodies  >5 publications with 4-1BB and Lung Neoplasms
 Nervous System Diseases Antibodies  >4 publications with 4-1BB and Nervous System Diseases
Organs/Tissues associated with anti-4-1BB antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >118 publications with 4-1BB and Blood
 Nerve Antibodies  >55 publications with 4-1BB and Nerve
 Bone Antibodies  >12 publications with 4-1BB and Bone
 Brain Antibodies  >5 publications with 4-1BB and Brain
 Eye Antibodies  >4 publications with 4-1BB and Eye
 Intestine Antibodies  >4 publications with 4-1BB and Intestine
 Stomach Antibodies  >3 publications with 4-1BB and Stomach
 Prostate Antibodies  >1 publications with 4-1BB and Prostate
 Cervix Antibodies  >1 publications with 4-1BB and Cervix
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