NP_001020241.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
40S ribosomal protein S14
NCBI Official Synonym Full Names
ribosomal protein S14
NCBI Official Synonym Symbols
NCBI Protein Information
40S ribosomal protein S14
UniProt Protein Name
40S ribosomal protein S14
UniProt Entry Name
RS14_HUMAN
NCBI Summary for RPS14
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for RPS14
RPS14: a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Protein type: RNA-binding; Ribosomal; Translation
Chromosomal Location of Human Ortholog: 5q31-q33
Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; mitochondrion; nucleolus
Molecular Function: mRNA 5'-UTR binding; protein binding; RNA binding; structural constituent of ribosome; translation regulator activity
Biological Process: cellular protein metabolic process; erythrocyte differentiation; gene expression; maturation of SSU-rRNA; maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); mRNA catabolic process, nonsense-mediated decay; negative regulation of transcription from RNA polymerase II promoter; regulation of translation; ribosomal small subunit assembly and maintenance; selenium metabolic process; selenocysteine metabolic process; SRP-dependent cotranslational protein targeting to membrane; translation; translational elongation; translational initiation; translational termination; viral infectious cycle; viral reproduction; viral transcription
Disease: Chromosome 5q Deletion Syndrome
Research Articles on RPS14
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Products associated with anti-RPS14 antibody
Pathways associated with anti-RPS14 antibody
Diseases associated with anti-RPS14 antibody
Organs/Tissues associated with anti-RPS14 antibody
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