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anti-HTR5A antibody :: Rabbit anti-Human 5-HT5A Receptor (HTR5A) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS395628
Immunohistochemistry (IHC)
Unit / Price
  DISCONTINUED
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 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

5-HT5A Receptor (HTR5A), Polyclonal Antibody

 Also Known As   

5-HT5A Receptor (HTR5A)

 Product Synonym Names    5-HT-5A; 5-HT5A; HTR5A; MGC138226
 Product Gene Name   

anti-HTR5A antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 7; NC_000007.13 (154862034..154879102). Location: 7q36.1
 OMIM    601305
 3D Structure    ModBase 3D Structure for P47898
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Immunoaffinity Purification
 Form/Format    Phosphate buffered saline containing 0.1% sodium azide
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 Immunogen    3rd cytoplasmic domain of human
 Positive Control    Human brain.
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 Preparation and Storage    Product should be stored at -70 degree C. Aliquot to avoid freeze/thaw cycles
 Other Notes    Small volumes of anti-HTR5A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-HTR5A antibody

   This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.
 Product Categories/Family for anti-HTR5A antibody    Antigen Immunoaffinity Purifed Polyclonal; Serotonin
 Applications Tested/Suitable for anti-HTR5A antibody   

Immunohistochemistry (IHC)

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 Immunohistochemistry (IHC) of anti-HTR5A antibody    HTR5A staining of formallin fixed paraffin embedded human brain (cerebellum) tissue at a dilution of 10 ug/ml. Antigen retrieval using a citrate buffer and steam/heat was utilized.
anti-HTR5A antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for HTR5A. It may not necessarily be applicable to this product.
 NCBI GI #    13236497
 NCBI GeneID    3361
 NCBI Accession #    NP_076917.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_024012.3 [Other Products]
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 UniProt Primary Accession #    P47898 [Other Products]
 UniProt Secondary Accession #    Q2M2D2 [Other Products]
 UniProt Related Accession #    P47898 [Other Products]
 Molecular Weight    40,255 Da
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 NCBI Official Full Name    5-hydroxytryptamine receptor 5A
 NCBI Official Synonym Full Names    5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
 NCBI Official Symbol    HTR5A [Similar Products]
 NCBI Official Synonym Symbols   
5-HT5A
[Similar Products]
 NCBI Protein Information    5-hydroxytryptamine receptor 5A; 5-HT-5; 5-HT-5A; serotonin receptor 5A
 UniProt Protein Name    5-hydroxytryptamine receptor 5A
 UniProt Synonym Protein Names   
Serotonin receptor 5A
 Protein Family    5-hydroxytryptamine receptor
 UniProt Gene Name    HTR5A [Similar Products]
 UniProt Synonym Gene Names    5-HT-5; 5-HT-5A; 5-HT5A [Similar Products]
 UniProt Entry Name    5HT5A_HUMAN
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 NCBI Summary for HTR5A    The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008]
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 UniProt Comments for HTR5A    Function: This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
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 Research Articles on HTR5A    1. Childhood anxiousness did not mediate the effects of HTR2A and HTR5A on mood disorders.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-HTR5A antibodyPathways associated with anti-HTR5A antibody
 Reference Product  PubMed Publications
 HTR1A antibody  >6 publications with HTR5A and HTR1A
 HTR1D antibody  >2 publications with HTR5A and HTR1D
 HTR1F antibody  >2 publications with HTR5A and HTR1F
 Products by Pathway  Pathway Diagram
 Amine Ligand-binding Receptors Pathway antibodies  Amine Ligand-binding Receptors Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Monoamine GPCRs Pathway antibodies  Monoamine GPCRs Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with anti-HTR5A antibodyOrgans/Tissues associated with anti-HTR5A antibody
 Disease Name  Pubmed Publications
 Nervous System Malformations Antibodies  >2 publications with HTR5A and Nervous System Malformations
 Aneuploidy Antibodies  >2 publications with HTR5A and Aneuploidy
 Cognition Disorders Antibodies  >1 publications with HTR5A and Cognition Disorders
 Autistic Disorder Antibodies  >1 publications with HTR5A and Autistic Disorder
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with HTR5A and Brain
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