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anti-ADCY1 antibody :: Rabbit anti-Human, Mouse A Cyclase I Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8521010 anti-ADCY1 antibody
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Cyclase I (ADCY1), Polyclonal Antibody

 Also Known As   

A Cyclase I Polyclonal Antibody

 Product Synonym Names    ADCY1; Adenylate cyclase type 1; ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca (2+)/calmodulin-activated adenylyl cyclase
 Product Gene Name   

anti-ADCY1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AC069008 Genomic DNA
 3D Structure    ModBase 3D Structure for Q08828
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Specificity    A Cyclase I Polyclonal Antibody detects endogenous levels of A Cyclase I protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from the Internal region of human A Cyclase I. at AA rangle: 200-280
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 Preparation and Storage    Store at -20 degree C/1 year
 Other Notes    Small volumes of anti-ADCY1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ADCY1 antibody   

Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)

 Application Notes for anti-ADCY1 antibody    Western Blot: 1/500 - 1/2000
Immunohistochemistry: 1/100 - 1/300
ELISA: 1/40000
Not yet tested in other applications.
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NCBI/Uniprot data below describe general gene information for ADCY1. It may not necessarily be applicable to this product.
 NCBI GI #    31083193
 NCBI GeneID    107
 NCBI Accession #    NP_066939.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_021116.2 [Other Products]
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 UniProt Primary Accession #    Q08828 [Other Products]
 UniProt Secondary Accession #    Q75MI1; A4D2L8 [Other Products]
 UniProt Related Accession #    Q08828 [Other Products]
 Molecular Weight    123.44
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 NCBI Official Full Name    adenylate cyclase type 1 isoform 1
 NCBI Official Synonym Full Names    adenylate cyclase 1
 NCBI Official Symbol    ADCY1 [Similar Products]
 NCBI Official Synonym Symbols   
AC1; DFNB44
[Similar Products]
 NCBI Protein Information    adenylate cyclase type 1
 UniProt Protein Name    Adenylate cyclase type 1
 UniProt Synonym Protein Names   
ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca(2+)/calmodulin-activated adenylyl cyclase
 Protein Family    Adenylate cyclase
 UniProt Gene Name    ADCY1 [Similar Products]
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 NCBI Summary for ADCY1    This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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 UniProt Comments for ADCY1    ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Protein type: Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin family

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: cytoplasm; integral to plasma membrane; plasma membrane

Molecular Function: adenylate cyclase activity; calcium- and calmodulin-responsive adenylate cyclase activity

Biological Process: activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cAMP-mediated signaling; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; regulation of circadian rhythm; renal water homeostasis

Disease: Deafness, Autosomal Recessive 44
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 Research Articles on ADCY1    1. Maps to 7p14.1-q11.22 between D7S2209 and marker D7S2435, maximum Lod score 5 for D7S1818.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ADCY1 antibodyPathways associated with anti-ADCY1 antibody
 Reference Product  PubMed Publications
 DRD4 antibody  >2 publications with ADCY1 and DRD4
 ADCY2 antibody  >2 publications with ADCY1 and ADCY2
 Products by Pathway  Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Adenylate Cyclase Activating Pathway antibodies  Adenylate Cyclase Activating Pathway Diagram
 Adenylate Cyclase Inhibitory Pathway antibodies  Adenylate Cyclase Inhibitory Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 CREB Phosphorylation Through The Activation Of Adenylate Cyclase Pathway antibodies  CREB Phosphorylation Through The Activation Of Adenylate Cyclase Pathway Diagram
Diseases associated with anti-ADCY1 antibodyOrgans/Tissues associated with anti-ADCY1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1 publications with ADCY1 and Neoplasms
 Nervous System Diseases Antibodies  >1 publications with ADCY1 and Nervous System Diseases
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >6 publications with ADCY1 and Eye
 Brain Antibodies  >6 publications with ADCY1 and Brain
 Embryonic Tissue Antibodies  >3 publications with ADCY1 and Embryonic Tissue
 Nerve Antibodies  >2 publications with ADCY1 and Nerve
 Kidney Antibodies  >2 publications with ADCY1 and Kidney
 Bone Antibodies  >1 publications with ADCY1 and Bone
 Heart Antibodies  >1 publications with ADCY1 and Heart
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