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anti-ADCY4 antibody :: Rabbit A Cyclase IV Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8521011 anti-ADCY4 antibody
Unit / Price
0.1 mg  /  $290 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

A Cyclase IV (ADCY4), Polyclonal Antibody

 Also Known As   

A Cyclase IV Polyclonal Antibody

 Product Synonym Names    ADCY4; Adenylate cyclase type 4; ATP pyrophosphate-lyase 4; Adenylate cyclase type IV; Adenylyl cyclase 4
 Product Gene Name   

anti-ADCY4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    AF497516 mRNA
 3D Structure    ModBase 3D Structure for Q8NFM4
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    A Cyclase IV Polyclonal Antibody detects endogenous levels of A Cyclase IV protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Immunogen    Synthesized peptide derived from the Internal region of human A Cyclase IV. at AA rangle: 170-250
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 Preparation and Storage    Store at -20 degree C/1 year
 Other Notes    Small volumes of anti-ADCY4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ADCY4 antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-ADCY4 antibody    Western Blot: 1/500 - 1/2000
ELISA: 1/20000
Not yet tested in other applications.
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NCBI/Uniprot data below describe general gene information for ADCY4. It may not necessarily be applicable to this product.
 NCBI GI #    310832386
 NCBI GeneID    196883
 NCBI Accession #    NP_001185497.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001198568.1 [Other Products]
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 UniProt Primary Accession #    Q8NFM4 [Other Products]
 UniProt Secondary Accession #    Q17R40; Q6ZTM6; Q96ML7; B3KV74; D3DS75 [Other Products]
 UniProt Related Accession #    Q8NFM4 [Other Products]
 Molecular Weight    119.794
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 NCBI Official Full Name    adenylate cyclase type 4
 NCBI Official Synonym Full Names    adenylate cyclase 4
 NCBI Official Symbol    ADCY4 [Similar Products]
 NCBI Official Synonym Symbols   
AC4
[Similar Products]
 NCBI Protein Information    adenylate cyclase type 4
 UniProt Protein Name    Adenylate cyclase type 4
 UniProt Synonym Protein Names   
ATP pyrophosphate-lyase 4; Adenylate cyclase type IV; Adenylyl cyclase 4
 Protein Family    Adenylate cyclase
 UniProt Gene Name    ADCY4 [Similar Products]
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 NCBI Summary for ADCY4    This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
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 UniProt Comments for ADCY4    ADCY4: This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Protein type: Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin family

Chromosomal Location of Human Ortholog: 14q12

Cellular Component: cytoplasm; membrane; plasma membrane

Molecular Function: adenylate cyclase activity; protein binding

Biological Process: activation of protein kinase A; adenylate cyclase activation; cAMP biosynthetic process; cAMP-mediated signaling; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; renal water homeostasis
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 Research Articles on ADCY4    1. AC4 and AC2, both isoforms stimulated by Gbetagamma, are expressed in bronchial nonlipid raft membrane fractions where they colocalize with and couple to prostanoid EP2 receptors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ADCY4 antibodyDiseases associated with anti-ADCY4 antibody
 Products by Pathway  Pathway Diagram
 Activation Of GABAB Receptors Pathway antibodies  Activation Of GABAB Receptors Pathway Diagram
 Adenylate Cyclase Activating Pathway antibodies  Adenylate Cyclase Activating Pathway Diagram
 Adenylate Cyclase Inhibitory Pathway antibodies  Adenylate Cyclase Inhibitory Pathway Diagram
 Aquaporin-mediated Transport Pathway antibodies  Aquaporin-mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Ca-dependent Events Pathway antibodies  Ca-dependent Events Pathway Diagram
 CaM Pathway antibodies  CaM Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with ADCY4 and Nervous System Diseases
Organs/Tissues associated with anti-ADCY4 antibody
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with ADCY4 and Kidney
 Embryonic Tissue Antibodies  >1 publications with ADCY4 and Embryonic Tissue
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