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| Product Name
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A Cyclase VII (ADCY7), Polyclonal Antibody
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| Also Known As
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A Cyclase VII Polyclonal Antibody
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| Product Synonym Names
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ADCY7; KIAA0037; Adenylate cyclase type 7; ATP pyrophosphate-lyase 7; Adenylate cyclase type VII; Adenylyl cyclase 7
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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 TOP
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| OMIM
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D25538 mRNA
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| 3D Structure
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ModBase 3D Structure for P51828
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| Clonality
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Polyclonal
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| Host
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Rabbit
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| Species Reactivity
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Human, Mouse
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| Specificity
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A Cyclase VII Polyclonal Antibody detects endogenous levels of A Cyclase VII protein.
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| Purity/Purification
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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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| Form/Format
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Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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| Concentration
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1 mg/ml (lot specific)
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| Immunogen
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Synthesized peptide derived from the Internal region of human A Cyclase VII. at AA rangle: 160-240
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| Preparation and Storage
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Store at -20 degree C/1 year
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| Other Notes
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Small volumes of anti-ADCY7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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TOP
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| Applications Tested/Suitable for anti-ADCY7 antibody
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Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
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| Application Notes for anti-ADCY7 antibody
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Immunohistochemistry: 1/100 - 1/300
Immunofluorescence: 1/200 - 1/1000
ELISA: 1/5000
Not yet tested in other applications.
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TOP
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| NCBI/Uniprot data below describe general gene information for ADCY7. It may not necessarily be applicable to this product. |
| NCBI GI #
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4557255
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| NCBI GeneID
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113
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| NCBI Accession #
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NP_001105.1
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_001114.4
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[Other Products]
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| UniProt Primary Accession #
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P51828
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[Other Products]
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| UniProt Secondary Accession #
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A0AVA6
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[Other Products]
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| UniProt Related Accession #
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P51828
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[Other Products]
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| Molecular Weight
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120.308
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TOP
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| NCBI Official Full Name
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adenylate cyclase type 7 isoform 1
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| NCBI Official Synonym Full Names
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adenylate cyclase 7
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| NCBI Official Symbol
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ADCY7
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[Similar Products]
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| NCBI Official Synonym Symbols
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AC7
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[Similar Products]
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| NCBI Protein Information
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adenylate cyclase type 7
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| UniProt Protein Name
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Adenylate cyclase type 7
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| UniProt Synonym Protein Names
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ATP pyrophosphate-lyase 7; Adenylate cyclase type VII; Adenylyl cyclase 7
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| Protein Family
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Adenylate cyclase
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| UniProt Gene Name
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ADCY7
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[Similar Products]
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| UniProt Synonym Gene Names
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KIAA0037
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[Similar Products]
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| NCBI Summary for ADCY7
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This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013]
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| UniProt Comments for ADCY7
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ADCY7: This is a membrane-bound, calcium-inhibitable adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein type: Adenylyl cyclase; EC 4.6.1.1; Lyase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Transporter; Transporter, aquaporin family
Chromosomal Location of Human Ortholog: 16q12.1
Cellular Component: integral to membrane; plasma membrane
Molecular Function: adenylate cyclase activity
Biological Process: activation of protein kinase A; adenylate cyclase activation; cAMP-mediated signaling; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of cAMP biosynthetic process; renal water homeostasis
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TOP
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| Research Articles on ADCY7
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1. The stronger TNF-alpha responses in young males compared to females may be partly associated with male-specific down-regulation of ADCY7 and ADCY9.
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TOP
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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TOP
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| Products associated with anti-ADCY7 antibody | Pathways associated with anti-ADCY7 antibody |
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| Diseases associated with anti-ADCY7 antibody | Organs/Tissues associated with anti-ADCY7 antibody |
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TOP
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Antibody 
