NP_064463.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
86,140 Da
NCBI Official Full Name
disintegrin and metalloproteinase domain-containing protein 1
NCBI Official Synonym Full Names
ADAM metallopeptidase domain 1A
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 1
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 1
UniProt Synonym Protein Names
Fertilin subunit alpha
UniProt Synonym Gene Names
NCBI Summary for ADAM1
membrane-anchored glycoprotein and metalloproteinase-like, disintegrin-like, cysteine-rich (MDC) family member that is localized on the sperm surface where it may play a role in fertilization [RGD, Feb 2006]
UniProt Comments for ADAM1
ADAM1A: May be involved in sperm-egg fusion.
Protein type: EC 3.4.24.-; Endoplasmic reticulum; Membrane protein, integral; Protease
Chromosomal Location of Human Ortholog: 12q16
Cellular Component: integral component of membrane; membrane raft
Molecular Function: metal ion binding; metalloendopeptidase activity; metallopeptidase activity
Biological Process: binding of sperm to zona pellucida; male gonad development; proteolysis
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Products associated with anti-ADAM1 antibody
Organs/Tissues associated with anti-ADAM1 antibody
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