EDL32851.1
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
78,557 Da
NCBI Official Full Name
a disintegrin and metallopeptidase domain 5
NCBI Official Synonym Full Names
a disintegrin and metallopeptidase domain 5
NCBI Protein Information
disintegrin and metalloproteinase domain-containing protein 5
UniProt Protein Name
Disintegrin and metalloproteinase domain-containing protein 5
UniProt Synonym Protein Names
Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein II; tMDC II
UniProt Synonym Gene Names
NCBI Summary for ADAM5
This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. This gene is located in a cluster of related ADAM genes on chromosome 8. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. [provided by RefSeq, May 2016]
UniProt Comments for ADAM5
ADAM5P: This is a non catalytic metalloprotease-like protein. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Protease
Chromosomal Location of Human Ortholog: 8 A2|8 13.26 cM
Cellular Component: integral component of membrane; membrane
Molecular Function: metalloendopeptidase activity; metallopeptidase activity; protein binding
Biological Process: proteolysis
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Pathways associated with anti-ADAM5 antibody
Diseases associated with anti-ADAM5 antibody
Organs/Tissues associated with anti-ADAM5 antibody
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