View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-A-RAF antibody :: Rabbit A-RAF Polyclonal Antibody Catalog # MBS9429224 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name A-RAF, Polyclonal Antibody Full Product Name A-RAF (Phospho-Thr214) Antibody Product Synonym Names A raf 1; A Raf proto oncogene serine/threonine protein kinase; ARAF 1; Araf; ARaf proto oncogene serine/threonine protein kinase; ARAF_HUMAN; ARAF1; Oncogene Araf1; Oncogene PKS2; PKS 2; PKS; PKS2; Proto oncogene Pks; Proto-oncogene A-Raf; Proto-oncogene A-Raf-1; Proto-oncogene Pks; RAFA 1; RAFA1; Ras binding protein DA Raf; Serine/threonine-protein kinase A-Raf; v raf murine sarcoma 3611 viral oncogene homolog; v raf murine sarcoma 3611 viral oncogene homolog 1; v raf oncogene homolog 1 (murine sarcoma 3611 virus); Product Gene Name anti-A-RAF antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM X04790 mRNA 3D Structure ModBase 3D Structure for P10398 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse, Rat Specificity Phospho-A-RAF (Phospho-Thr214) Antibody detects endogenous levels of A-RAF only when phosphorylated at Thr214 Purity/Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns. Form/Format In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Concentration 1.0mg/mL (lot specific) Immunogen A synthesized peptide derived from human A-RAF around the phosphorylation site of Thr214 Immunogen Type Peptide Preparation and Storage Store at -20 degree C. Other Notes Small volumes of anti-A-RAF antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Product Categories/Family for anti-A-RAF antibody Phospho-specific Ab Applications Tested/Suitable for anti-A-RAF antibody Western Blot (WB) Application Notes for anti-A-RAF antibody WB: 1:500-1:2000 Western Blot (WB) of anti-A-RAF antibody Western blot analysis of Phospho-A-RAF (Thr214) in lysates of HeLa, using Phospho-A-RAF (Thr214) Antibody(13072). TOP NCBI/Uniprot data below describe general gene information for A-RAF. It may not necessarily be applicable to this product. NCBI GI # 371875793 NCBI GeneID 369 NCBI Accession # NP_001243125.1 [Other Products] NCBI GenBank Nucleotide # NM_001256196.1 [Other Products] UniProt Primary Accession # P10398 [Other Products] UniProt Secondary Accession # P07557; Q5H9B2; Q5H9B3[Other Products] UniProt Related Accession # P10398[Other Products] Molecular Weight 68 TOP NCBI Official Full Name serine/threonine-protein kinase A-Raf isoform 2 NCBI Official Synonym Full Names A-Raf proto-oncogene, serine/threonine kinase NCBI Official Symbol ARAF [Similar Products] NCBI Official Synonym Symbols PKS2; A-RAF; ARAF1; RAFA1 [Similar Products] NCBI Protein Information serine/threonine-protein kinase A-Raf UniProt Protein Name Serine/threonine-protein kinase A-Raf UniProt Synonym Protein Names Proto-oncogene A-Raf; Proto-oncogene A-Raf-1; Proto-oncogene Pks UniProt Gene Name ARAF [Similar Products] UniProt Synonym Gene Names ARAF1; PKS; PKS2 [Similar Products] TOP NCBI Summary for A-RAF This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2012] TOP UniProt Comments for A-RAF Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Research Articles on A-RAF 1. The constitutive or induced re-localization of A-Raf to the plasma membrane compromises its ability to efficiently sequester and inactivate MST2, thus rendering cells susceptible to apoptosis TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-A-RAF antibody Reference Product PubMed Publications BRAF antibody >41 publications with A-RAF and BRAF KRAS antibody >14 publications with A-RAF and KRAS NRAS antibody >10 publications with A-RAF and NRAS MAP2K1 antibody >8 publications with A-RAF and MAP2K1 HRAS antibody >3 publications with A-RAF and HRAS MAP2K2 antibody >2 publications with A-RAF and MAP2K2 MAPK1 antibody >1 publications with A-RAF and MAPK1 Pathways associated with anti-A-RAF antibody Products by Pathway Pathway Diagram ARMS-mediated Activation Pathway antibodies ARMS-mediated Activation Pathway Diagram Acute Myeloid Leukemia Pathway antibodies Acute Myeloid Leukemia Pathway Diagram Acute Myeloid Leukemia Pathway antibodies Acute Myeloid Leukemia Pathway Diagram Alcoholism Pathway antibodies Alcoholism Pathway Diagram Alcoholism Pathway antibodies Alcoholism Pathway Diagram Axon Guidance Pathway antibodies Axon Guidance Pathway Diagram Bladder Cancer Pathway antibodies Bladder Cancer Pathway Diagram Bladder Cancer Pathway antibodies Bladder Cancer Pathway Diagram Breast Cancer Pathway antibodies Breast Cancer Pathway Diagram Breast Cancer Pathway antibodies Breast Cancer Pathway Diagram Diseases associated with anti-A-RAF antibody Disease Name Pubmed Publications Lung Diseases Antibodies >12 publications with A-RAF and Lung Diseases Necrosis Antibodies >10 publications with A-RAF and Necrosis Adenocarcinoma Antibodies >8 publications with A-RAF and Adenocarcinoma Inflammation Antibodies >5 publications with A-RAF and Inflammation Fibrosis Antibodies >4 publications with A-RAF and Fibrosis Weight Loss Antibodies >4 publications with A-RAF and Weight Loss Cardiovascular Diseases Antibodies >4 publications with A-RAF and Cardiovascular Diseases Lung Neoplasms Antibodies >4 publications with A-RAF and Lung Neoplasms Hypertension Antibodies >3 publications with A-RAF and Hypertension Liver Diseases Antibodies >2 publications with A-RAF and Liver Diseases Organs/Tissues associated with anti-A-RAF antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >31 publications with A-RAF and Blood Lung Antibodies >12 publications with A-RAF and Lung Vascular Antibodies >12 publications with A-RAF and Vascular Bone Antibodies >8 publications with A-RAF and Bone Spleen Antibodies >7 publications with A-RAF and Spleen Stomach Antibodies >5 publications with A-RAF and Stomach Skin Antibodies >5 publications with A-RAF and Skin Liver Antibodies >5 publications with A-RAF and Liver Brain Antibodies >5 publications with A-RAF and Brain Bone Marrow Antibodies >4 publications with A-RAF and Bone Marrow TOP © 2006-24 MyBioSource.com. 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