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anti-AADAC antibody :: Rabbit anti-Human AADAC Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS856326
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AADAC, Polyclonal Antibody

 Also Known As   

AADAC Antibody

 Product Gene Name   

anti-AADAC antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    600338
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Lyophilized AADAC antibody purified by protein A column containing 0.02% NaN3
 Concentration    100ug/200ul (lot specific)
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 Source Note    Rabbit polyclonal AADAC (1) antibody was raised against a recombinate human AADAC protein 200-399aa (BC032309).
 Reactivity Note    Predicted: Mouse, Rat; Not yet tested in other species.
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
 Other Notes    Small volumes of anti-AADAC antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-AADAC antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-AADAC antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-AADAC antibody    ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Immunohistochemistry: 1:100-500
Optimal dilutions/concentrations should be determined by the end user.
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 Testing Data of anti-AADAC antibody    anti-AADAC antibody Testing Data image
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 Testing Data #2 of anti-AADAC antibody    anti-AADAC antibody Testing Data #2 image
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NCBI/Uniprot data below describe general gene information for AADAC. It may not necessarily be applicable to this product.
 NCBI GI #    68299767
 NCBI GeneID    13
 NCBI Accession #    NP_001077.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001086.2 [Other Products]
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 UniProt Secondary Accession #    Q8N1A9; A8K3L3; D3DNJ6 [Other Products]
 UniProt Related Accession #    P22760 [Other Products]
 Molecular Weight    45,734 Da
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 NCBI Official Full Name    arylacetamide deacetylase
 NCBI Official Synonym Full Names    arylacetamide deacetylase
 NCBI Official Symbol    AADAC [Similar Products]
 NCBI Official Synonym Symbols   
DAC; CES5A1
[Similar Products]
 NCBI Protein Information    arylacetamide deacetylase; arylacetamide deacetylase (esterase)
 UniProt Protein Name    Arylacetamide deacetylase
 Protein Family    Arylacetamide deacetylase
 UniProt Gene Name    AADAC [Similar Products]
 UniProt Synonym Gene Names    DAC [Similar Products]
 UniProt Entry Name    AAAD_HUMAN
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 NCBI Summary for AADAC    Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]
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 UniProt Comments for AADAC    AADAC: Arylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionaly causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores. Belongs to the 'GDXG' lipolytic enzyme family.

Protein type: Deacetylase; Membrane protein, integral; Lipase; Motility/polarity/chemotaxis; EC 3.1.1.3; Endoplasmic reticulum

Chromosomal Location of Human Ortholog: 3q25.1

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: deacetylase activity; triacylglycerol lipase activity; serine hydrolase activity; lipase activity; catalytic activity

Biological Process: metabolic process
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 Research Articles on AADAC    1. Translational N-glycosylation of AADAC plays a crucial role in regulating AADAC enzyme activity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with anti-AADAC antibodyOrgans/Tissues associated with anti-AADAC antibody
 Disease Name  Pubmed Publications
 Hepatitis Antibodies  >1 publications with AADAC and Hepatitis
 Carcinoma, Hepatocellular Antibodies  >1 publications with AADAC and Carcinoma, Hepatocellular
 Fatty Liver Antibodies  >1 publications with AADAC and Fatty Liver
 Liver Neoplasms Antibodies  >1 publications with AADAC and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with AADAC and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >16 publications with AADAC and Liver
 Adipose Tissue Antibodies  >1 publications with AADAC and Adipose Tissue
 Connective Tissue Antibodies  >1 publications with AADAC and Connective Tissue
 Pancreas Antibodies  >1 publications with AADAC and Pancreas
 Adrenal Gland Antibodies  >1 publications with AADAC and Adrenal Gland
 Intestine Antibodies  >1 publications with AADAC and Intestine
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