NP_065796.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
107,340 Da
NCBI Official Full Name
alanine--tRNA ligase, mitochondrial
NCBI Official Synonym Full Names
alanyl-tRNA synthetase 2, mitochondrial
NCBI Official Synonym Symbols
AARSL; LKENP; COXPD8; MTALARS; MT-ALARS [Similar Products]
NCBI Protein Information
alanine--tRNA ligase, mitochondrial
UniProt Protein Name
Alanine--tRNA ligase, mitochondrial
UniProt Synonym Protein Names
Alanyl-tRNA synthetase
UniProt Synonym Gene Names
NCBI Summary for AARS2
The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. [provided by RefSeq, Dec 2011]
UniProt Comments for AARS2
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
Research Articles on AARS2
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Pathways associated with anti-AARS2 antibody
Diseases associated with anti-AARS2 antibody
Organs/Tissues associated with anti-AARS2 antibody
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