Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow AATK rightarrow Polyclonal AATK  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • B2M cDNA Clone
 • PROLYL HYDROXYLASE 2 (EGLN1) Antibody
 • von Willebrand Factor cleaving protease, ADAMTS-13-vWF-cp ELISA Kit
 • AK2 Antibody
 • GAPDH mAb Antibody
 • Complement fragment 5a (C5a) ELISA Kit
 • ZAR1-like protein (ZAR1L) Recombinant Protein
 • HIV1 gp120 Recombinant Protein
 • prothrombin fragment 1+2 (F1-2) ELISA Kit
 • Antigen peptide transporter 1 (Tap1) Recombinant Protein
 • Leukotriene B4 receptor 1, LTB4R ELISA Kit
 • Vitamin B6 (VB6) ELISA Kit
 • (3R)-hydroxymyristoyl-[acyl -carrier-protein] dehydratase (lh... Recombinant Protein
 • M13 BACTERIOPHAGE Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-AATK antibody :: Rabbit AATK Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2520162
Immunohistochemistry (IHC)
Unit / Price
0.06 mL  /  $195 +1 FREE 8GB USB
0.12 mL  /  $270 +1 FREE 8GB USB
0.2 mL  /  $435 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

AATK, Polyclonal Antibody

 Also Known As   

AATK Polyclonal Antibody

 Product Synonym Names    LMR1; AATYK; LMTK1; p35BP; AATYK1
 Product Gene Name   

anti-AATK antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    605276
Section Bar
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
Section Bar
 Purity/Purification    Antigen affinity purification
 Concentration    2.9mg/mL (lot specific)
Section Bar
 Immunogen    Synthetic peptide of human AATK
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Section Bar
 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-AATK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Product Description specifically for anti-AATK antibody

   The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene.
 Applications Tested/Suitable for anti-AATK antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-AATK antibody    IHC: 1:50-1:200
Section Bar
 Immunohistochemistry (IHC) of anti-AATK antibody    Immunohistochemistry of Human liver cancer using AATK Polyclonal Antibody at dilution of 1:45
anti-AATK antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for AATK. It may not necessarily be applicable to this product.
 NCBI GI #    28703754
 NCBI GeneID    9625
 NCBI Accession #    AAH47378.1 [Other Products]
Section Bar
 UniProt Secondary Accession #    O75136; Q6ZN31; Q86X28 [Other Products]
 UniProt Related Accession #    Q6ZMQ8 [Other Products]
 Molecular Weight    93,226 Da
Table BarTOPTable Bar
 NCBI Official Full Name    AATK protein, partial
 NCBI Official Synonym Full Names    apoptosis-associated tyrosine kinase
 NCBI Official Symbol    AATK [Similar Products]
 NCBI Official Synonym Symbols   
LMR1; AATYK; LMTK1; p35BP; AATYK1; PPP1R77
[Similar Products]
 NCBI Protein Information    serine/threonine-protein kinase LMTK1; CDK5-binding protein; brain apoptosis-associated tyrosine kinase; lemur tyrosine kinase 1; p35-binding protein; protein phosphatase 1, regulatory subunit 77
 UniProt Protein Name    Serine/threonine-protein kinase LMTK1
 UniProt Synonym Protein Names   
Apoptosis-associated tyrosine kinase; AATYK; Brain apoptosis-associated tyrosine kinase; CDK5-binding protein; Lemur tyrosine kinase 1; p35-binding protein; p35BP
 Protein Family    Serine/threonine-protein kinase
 UniProt Gene Name    AATK [Similar Products]
 UniProt Synonym Gene Names    AATYK; KIAA0641; LMR1; LMTK1; AATYK; p35BP [Similar Products]
 UniProt Entry Name    LMTK1_HUMAN
Section Bar
 NCBI Summary for AATK    The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Section Bar
 UniProt Comments for AATK    Lmr1: a protein kinase kinase of the Lmr family. Predominantly expressed in the nervous system and is involved in neurite extension and apoptosis of cerebellar granule cells. Contains a tyrosine kinase domain at the N-terminal end and a proline-rich domain at the C-terminal end. May be necessary for the induction of growth arrest and/or apoptosis of myeloid cells induced by cytokine withdrawal, such as IL3, and during G-CSF-induced terminal differentiation of myeloblasts to granulocytes. Four alternatively spliced isoforms have been reported.

Protein type: Kinase, protein; EC 2.7.11.1; Protein kinase, TK; Membrane protein, integral; Protein kinase, tyrosine (receptor); TK group; Lmr family

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: recycling endosome; perinuclear region of cytoplasm; endoplasmic reticulum; integral to membrane

Molecular Function: protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; ATP binding

Biological Process: neuron apoptosis; negative regulation of axon extension; brain development; Rab protein signal transduction
Table BarTOPTable Bar
 Research Articles on AATK    1. This paper deals with the mouse ortholog.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-AATK antibodyDiseases associated with anti-AATK antibody
 Reference Product  PubMed Publications
 CDK5 antibody  >4 publications with AATK and CDK5
 STK39 antibody  >1 publications with AATK and STK39
 Disease Name  Pubmed Publications
 Abnormalities, Drug-Induced Antibodies  >1 publications with AATK and Abnormalities, Drug-Induced
 Intestinal Neoplasms Antibodies  >1 publications with AATK and Intestinal Neoplasms
 Insulin Resistance Antibodies  >1 publications with AATK and Insulin Resistance
 Hyperplasia Antibodies  >1 publications with AATK and Hyperplasia
 Inflammation Antibodies  >1 publications with AATK and Inflammation
Organs/Tissues associated with anti-AATK antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >14 publications with AATK and Brain
 Nerve Antibodies  >6 publications with AATK and Nerve
 Intestine Antibodies  >1 publications with AATK and Intestine
 Pancreas Antibodies  >1 publications with AATK and Pancreas
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions