Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ABCA3 rightarrow Polyclonal ABCA3  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • budding uninhibited by benzimidazoles 1 homolog beta (yeast)... ELISA Kit
 • Kynureninase (KYNU) ELISA Kit
 • Matrix metalloproteinase-9 (MMP9) Recombinant Protein
 • Butyrophilin subfamily 2 member A2 (BTN2A2) ELISA Kit
 • (Rhesus macaque) Gamma-crystallin C (CRYGC) Recombinant Protein
 • CENPB ELISA Kit
 • Kidney Injury Molecule 1 (Kim-1) ELISA Kit
 • cadherln related neuronal receptor1, CNR 1 (CNR1) ELISA Kit
 • alpha crystallin B (CRYAB) Recombinant Protein
 • ACE ELISA Kit
 • Cytochrome P450 2C9 (CP2C9) Antibody
 • JAK1 Antibody
 • Sphingosine kinase 2 (SPHK2) ELISA Kit
 • VAMP 2 (VAMP2) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ABCA3 antibody :: Rabbit ABCA3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS855986
Testing Data
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCA3, Polyclonal Antibody

★Popular Item★
 Also Known As   

ABCA3 Antibody

 Product Gene Name   

anti-ABCA3 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    gene 610921
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Reacts with Human
Predicted: Mouse, Rat
Not yet tested on other species
Section Bar
 Form/Format    Lyophilized ABCA3 antibody purified by protein A column containing 0.02% NaN3
Section Bar
 Source    Rabbit polyclonal ABCA3 (1) antibody was raised against a recombinate human ABCA3 protein 38-209aa (BC062779).
Section Bar
 Preparation and Storage    Dilution instruction and storage: Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at -20C after reconstution.
Avoid repeated freeze/defrost cycles.
 Other Notes    Small volumes of anti-ABCA3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Product Categories/Family for anti-ABCA3 antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-ABCA3 antibody   

Western Blot (WB)

 Application Notes for anti-ABCA3 antibody    ELISA titer: 1:10,000-1:80,000
Western blot analysis: 1:1,000-1:2,000
Optimal dilutions/concentrations should be determined by the end user.
Section Bar
 Testing Data of anti-ABCA3 antibody    anti-ABCA3 antibody Testing Data image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ABCA3. It may not necessarily be applicable to this product.
 NCBI GI #    116734710
 NCBI GeneID    21
 NCBI Accession #    BC062779 [Other Products]
 NCBI GenBank Nucleotide #    NM_001089.2 [Other Products]
Section Bar
 UniProt Secondary Accession #    Q54A95; Q6P5P9; Q92473; B2RU09 [Other Products]
 UniProt Related Accession #    Q99758 [Other Products]
Table BarTOPTable Bar
 NCBI Official Full Name    ATP-binding cassette sub-family A member 3
 NCBI Official Synonym Full Names    ATP-binding cassette, sub-family A (ABC1), member 3
 NCBI Official Symbol    ABCA3 [Similar Products]
 NCBI Official Synonym Symbols   
ABC3; ABC-C; SMDP3; LBM180; EST111653
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family A member 3; ABC transporter 3; ABC-C transporter; ATP-binding cassette transporter 3
 UniProt Protein Name    ATP-binding cassette sub-family A member 3
 UniProt Synonym Protein Names   
ABC-C transporter; ATP-binding cassette transporter 3; ATP-binding cassette 3
 Protein Family    ABC transporter A family
 UniProt Gene Name    ABCA3 [Similar Products]
 UniProt Synonym Gene Names    ABC3; ATP-binding cassette 3 [Similar Products]
 UniProt Entry Name    ABCA3_HUMAN
Section Bar
 NCBI Summary for ABCA3    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for ABCA3    ABCA3: Plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol. Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3 (SMDP3); also called pulmonary alveolar proteinosis due to ABCA3 deficiency. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress. Belongs to the ABC transporter superfamily. ABCA family.

Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, ABC family

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: extracellular space; membrane; plasma membrane; integral to membrane

Molecular Function: transporter activity; ATPase activity, coupled to transmembrane movement of substances; ATP binding

Biological Process: response to drug; metabolic process; transport; transmembrane transport

Disease: Surfactant Metabolism Dysfunction, Pulmonary, 3
Table BarTOPTable Bar
 

Product References and Citations for anti-ABCA3 antibody

   (1) Strausberg,R.L., Feingold,E.A., Grouse,L.H., et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
Section Bar
 Research Articles on ABCA3    1. Two siblings are described who were homozygous for a 5,983 bp deletion in ABCA3 including exons 2-5 as well as the start AUG codon and a putative Golgi exit signal motif.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-ABCA3 antibodyPathways associated with anti-ABCA3 antibody
 Reference Product  PubMed Publications
 SFTPC antibody  >31 publications with ABCA3 and SFTPC
 SFTPB antibody  >16 publications with ABCA3 and SFTPB
 NKX2-1 antibody  >7 publications with ABCA3 and NKX2-1
 LAMP3 antibody  >4 publications with ABCA3 and LAMP3
 NFATC3 antibody  >2 publications with ABCA3 and NFATC3
 STAT3 antibody  >2 publications with ABCA3 and STAT3
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 ABCA Transporters In Lipid Homeostasis Pathway antibodies  ABCA Transporters In Lipid Homeostasis Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with anti-ABCA3 antibodyOrgans/Tissues associated with anti-ABCA3 antibody
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >104 publications with ABCA3 and Lung Diseases
 Fibrosis Antibodies  >14 publications with ABCA3 and Fibrosis
 Inflammation Antibodies  >8 publications with ABCA3 and Inflammation
 Brain Diseases Antibodies  >8 publications with ABCA3 and Brain Diseases
 Death Antibodies  >8 publications with ABCA3 and Death
 Lung Neoplasms Antibodies  >7 publications with ABCA3 and Lung Neoplasms
 Hyperplasia Antibodies  >6 publications with ABCA3 and Hyperplasia
 Adenocarcinoma Antibodies  >5 publications with ABCA3 and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >4 publications with ABCA3 and Cardiovascular Diseases
 Heart Diseases Antibodies  >3 publications with ABCA3 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >131 publications with ABCA3 and Lung
 Brain Antibodies  >15 publications with ABCA3 and Brain
 Thyroid Antibodies  >14 publications with ABCA3 and Thyroid
 Vascular Antibodies  >9 publications with ABCA3 and Vascular
 Kidney Antibodies  >7 publications with ABCA3 and Kidney
 Heart Antibodies  >6 publications with ABCA3 and Heart
 Skin Antibodies  >5 publications with ABCA3 and Skin
 Liver Antibodies  >4 publications with ABCA3 and Liver
 Pancreas Antibodies  >3 publications with ABCA3 and Pancreas
 Testis Antibodies  >3 publications with ABCA3 and Testis
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions