NP_758424.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
99,273 Da
NCBI Official Full Name
ATP-binding cassette sub-family A member 5
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family A (ABC1), member 5
NCBI Protein Information
ATP-binding cassette sub-family A member 5; ATP-binding cassette A5
UniProt Protein Name
ATP-binding cassette sub-family A member 5
UniProt Entry Name
ABCA5_HUMAN
NCBI Summary for ABCA5
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCA5
ABCA5: May play a role in the processing of autolysosomes. Belongs to the ABC transporter superfamily. ABCA family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Transporter, ABC family; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 17q24.3
Cellular Component: Golgi membrane; lysosomal membrane; lysosome; late endosome membrane; late endosome; integral to membrane
Molecular Function: transporter activity; ATPase activity; ATP binding
Biological Process: reverse cholesterol transport; metabolic process; cholesterol efflux
Research Articles on ABCA5
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-ABCA5 antibody
Pathways associated with anti-ABCA5 antibody
Diseases associated with anti-ABCA5 antibody
Organs/Tissues associated with anti-ABCA5 antibody
|