NP_525023.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,356 Da
NCBI Official Full Name
ATP-binding cassette sub-family A member 6
NCBI Official Synonym Full Names
ATP binding cassette subfamily A member 6
NCBI Official Synonym Symbols
NCBI Protein Information
ATP-binding cassette sub-family A member 6
UniProt Protein Name
ATP-binding cassette sub-family A member 6
NCBI Summary for ABCA6
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24 and may play a role in macrophage lipid homeostasis. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCA6
ABCA6: Probable transporter which may play a role in macrophage lipid homeostasis. Belongs to the ABC transporter superfamily. ABCA family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family
Chromosomal Location of Human Ortholog: 17q24.2-q24.3
Cellular Component: intracellular membrane-bound organelle
Molecular Function: ATPase activity, coupled to transmembrane movement of substances
Biological Process: lipid transport
Research Articles on ABCA6
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Pathways associated with anti-ABCA6 antibody
Diseases associated with anti-ABCA6 antibody
Organs/Tissues associated with anti-ABCA6 antibody
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