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anti-ABCB10 antibody :: Goat ABCB10 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS619325 anti-ABCB10 antibody
Unit / Price
0.1 mg  /  $625 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCB10, Polyclonal Antibody

 Also Known As   

ABCB10 (ABCB10 ATP Binding Cassette, Sub-family B (MDR/TAP) Member 10, ATP-binding Cassette Sub-family B Member 10 Mitochondrial, ABCB 10, ATP-binding Cassette Transporter 10, ABC Transporter 10 Protein, EST20237, Mitochondrial ATP Binding Cassette 2, M A

 Product Synonym Names    Anti -ABCB10 (ABCB10 ATP Binding Cassette, Sub-family B (MDR/TAP) Member 10, ATP-binding Cassette Sub-family B Member 10 Mitochondrial, ABCB 10, ATP-binding Cassette Transporter 10, ABC Transporter 10 Protein, EST20237, Mitochondrial ATP Binding Cassette 2, M A
 Product Gene Name   

anti-ABCB10 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 1; NC_000001.10 (229652329..229694442, complement). Location: 1q42.13
 OMIM    605454
 3D Structure    ModBase 3D Structure for Q9NRK6
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes human ABCB10. Species Crossreactivity: Mouse and rat.
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a liquid in Tris saline 0.5 mg/ml, 0.02% sodium azide, pH 7.3, 0.5% BSA.
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 Immunogen    Synthetic peptide of ABCB10.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
 Other Notes    Small volumes of anti-ABCB10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ABCB10 antibody

   The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.
 Product Categories/Family for anti-ABCB10 antibody    Antibodies; Abs to Multi Drug Resistance (MDR)
 Applications Tested/Suitable for anti-ABCB10 antibody   

ELISA (EL/EIA)

 Application Notes for anti-ABCB10 antibody    Suitable for use in ELISA.
Dilution: ELISA: 1:64000
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NCBI/Uniprot data below describe general gene information for ABCB10. It may not necessarily be applicable to this product.
 NCBI GI #    171184400
 NCBI GeneID    23456
 NCBI Accession #    NP_036221.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_012089.2 [Other Products]
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 UniProt Primary Accession #    Q9NRK6 [Other Products]
 UniProt Secondary Accession #    Q13040; Q6P1Q8; Q9H3V0 [Other Products]
 UniProt Related Accession #    Q6ZMF8; Q9BXW0; Q9NRK6 [Other Products]
 Molecular Weight    79,148 Da [Similar Products]
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 NCBI Official Full Name    ATP-binding cassette sub-family B member 10, mitochondrial
 NCBI Official Synonym Full Names    ATP-binding cassette, sub-family B (MDR/TAP), member 10
 NCBI Official Symbol    ABCB10 [Similar Products]
 NCBI Official Synonym Symbols   
M-ABC2; MTABC2; EST20237
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family B member 10, mitochondrial; OTTHUMP00000037475; ABC transporter 10 protein; ATP-binding cassette transporter 10; mitochondrial ATP-binding cassette 2
 UniProt Protein Name    ATP-binding cassette sub-family B member 10, mitochondrial
 UniProt Synonym Protein Names   
ATP-binding cassette transporter 10; ABC transporter 10 protein; Mitochondrial ATP-binding cassette 2
 Protein Family    ABC transporter B family
 UniProt Gene Name    ABCB10 [Similar Products]
 UniProt Entry Name    ABCBA_HUMAN
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 NCBI Summary for ABCB10    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq]
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 UniProt Comments for ABCB10    ABCB10: May mediate critical mitochondrial transport functions related to heme biosynthesis. Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.

Protein type: Membrane protein, multi-pass; Hydrolase; Mitochondrial; Transporter; Transporter, ABC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q42.13

Cellular Component: mitochondrial inner membrane

Molecular Function: protein homodimerization activity; ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATP binding

Biological Process: metabolic process; transport; transmembrane transport
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 Research Articles on ABCB10    1. mutations in ABCB8 and ABCB10 is not associated with acute myeloid leukemia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ABCB10 antibodyDiseases associated with anti-ABCB10 antibody
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with ABCB10 and Neoplasms
 Leukemia, Myeloid, Acute Antibodies  >3 publications with ABCB10 and Leukemia, Myeloid, Acute
 Leukemia Antibodies  >3 publications with ABCB10 and Leukemia
 Leukemia, Myeloid Antibodies  >3 publications with ABCB10 and Leukemia, Myeloid
 Liver Diseases Antibodies  >1 publications with ABCB10 and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with ABCB10 and Liver Neoplasms
 Adenocarcinoma Antibodies  >1 publications with ABCB10 and Adenocarcinoma
 Drug Toxicity Antibodies  >1 publications with ABCB10 and Drug Toxicity
 Carcinoma, Hepatocellular Antibodies  >1 publications with ABCB10 and Carcinoma, Hepatocellular
 Carcinoma Antibodies  >1 publications with ABCB10 and Carcinoma
Organs/Tissues associated with anti-ABCB10 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6 publications with ABCB10 and Blood
 Liver Antibodies  >3 publications with ABCB10 and Liver
 Bone Marrow Antibodies  >2 publications with ABCB10 and Bone Marrow
 Bone Antibodies  >2 publications with ABCB10 and Bone
 Intestine Antibodies  >1 publications with ABCB10 and Intestine
 Skin Antibodies  >1 publications with ABCB10 and Skin
 Embryonic Tissue Antibodies  >1 publications with ABCB10 and Embryonic Tissue
 Vascular Antibodies  >1 publications with ABCB10 and Vascular
 Brain Antibodies  >1 publications with ABCB10 and Brain
 Heart Antibodies  >1 publications with ABCB10 and Heart
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