NP_001135977.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
ATP-binding cassette sub-family G member 4
NCBI Official Synonym Full Names
ATP-binding cassette, sub-family G (WHITE), member 4
NCBI Official Synonym Symbols
NCBI Protein Information
ATP-binding cassette sub-family G member 4
UniProt Protein Name
ATP-binding cassette sub-family G member 4
UniProt Synonym Gene Names
UniProt Entry Name
ABCG4_HUMAN
NCBI Summary for ABCG4
The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
UniProt Comments for ABCG4
ABCG4: May be involved in macrophage lipid homeostasis. Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
Protein type: Transporter, ABC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: integral to membrane; plasma membrane
Molecular Function: protein binding; protein homodimerization activity; protein heterodimerization activity; cholesterol transporter activity; ATPase activity; ATP binding
Biological Process: metabolic process; cholesterol efflux; transmembrane transport
Product References and Citations for anti-ABCG4 antibody
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) McGeachie, M., et al. Circulation 120(24):2448-2454(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009) Koshiba, S., et al. Xenobiotica 38 (7-8), 863-888 (2008) :
Research Articles on ABCG4
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Products associated with anti-ABCG4 antibody
Pathways associated with anti-ABCG4 antibody
Diseases associated with anti-ABCG4 antibody
Organs/Tissues associated with anti-ABCG4 antibody
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