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anti-ABCG8 antibody :: Rabbit anti-Human ABCG8 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS851228
Testing Data
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABCG8, Polyclonal Antibody

 Also Known As   

ABCG8 Antibody

 Product Gene Name   

anti-ABCG8 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    210250
 3D Structure    ModBase 3D Structure for Q9H221
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Form/Format    Purified by protein A column containing 0.02% NaN3
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.
 Other Notes    Small volumes of anti-ABCG8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ABCG8 antibody

   Rabbit polyclonal ABCG8(1) antibody was raised against a peptide corresponding to C terminal residues of human ABCG8.
 Product Categories/Family for anti-ABCG8 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-ABCG8 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-ABCG8 antibody    Peptide ELISA: 1:160,000
WB: 1:1,000-1:2,000
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 Testing Data of anti-ABCG8 antibody    anti-ABCG8 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for ABCG8. It may not necessarily be applicable to this product.
 NCBI GI #    11967971
 NCBI GeneID    64241
 NCBI Accession #    NP_071882.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_022437.2 [Other Products]
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 UniProt Primary Accession #    Q9H221 [Other Products]
 UniProt Secondary Accession #    Q53QN8 [Other Products]
 UniProt Related Accession #    Q9H221 [Other Products]
 Molecular Weight    75,592 Da
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 NCBI Official Full Name    ATP-binding cassette sub-family G member 8 isoform 1
 NCBI Official Synonym Full Names    ATP binding cassette subfamily G member 8
 NCBI Official Symbol    ABCG8 [Similar Products]
 NCBI Official Synonym Symbols   
GBD4; STSL
[Similar Products]
 NCBI Protein Information    ATP-binding cassette sub-family G member 8
 UniProt Protein Name    ATP-binding cassette sub-family G member 8
 UniProt Synonym Protein Names   
Sterolin-2
 Protein Family    ABC transporter G family
 UniProt Gene Name    ABCG8 [Similar Products]
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 NCBI Summary for ABCG8    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]
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 UniProt Comments for ABCG8    ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg2+- and ATP-dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:11099417, PubMed:11452359, PubMed:27144356, PubMed:15054092). Required for normal sterol homeostasis (PubMed:11099417, PubMed:11452359, PubMed:15054092). The heterodimer with ABCG5 has ATPase activity (PubMed:16893193, PubMed:20210363, PubMed:27144356).
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Product References and Citations for anti-ABCG8 antibody

   (1) Muller, M., Klein, I., Kopacsi, S., et al. Co-expression of human ABCG5 and ABCG8 in insect cells generates an androstan stimulated membrane ATPase activity. FEBS Lett.2006; 580 (26): 6139-6144.
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 Research Articles on ABCG8    1. Case Reports: compound heterozygous for nonsense mutations in ABCG8 responsible for sitosterolemia.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ABCG8 antibodyPathways associated with anti-ABCG8 antibody
 Reference Product  PubMed Publications
 ABCG5 antibody  >393 publications with ABCG8 and ABCG5
 NPC1L1 antibody  >76 publications with ABCG8 and NPC1L1
 CYP7A1 antibody  >39 publications with ABCG8 and CYP7A1
 SCARB1 antibody  >16 publications with ABCG8 and SCARB1
 SREBF1 antibody  >11 publications with ABCG8 and SREBF1
 SREBF2 antibody  >5 publications with ABCG8 and SREBF2
 ABCF1 antibody  >4 publications with ABCG8 and ABCF1
 GATA4 antibody  >3 publications with ABCG8 and GATA4
 NR1H3 antibody  >2 publications with ABCG8 and NR1H3
 Products by Pathway  Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters Pathway antibodies  ABC Transporters Pathway Diagram
 ABC Transporters In Lipid Homeostasis Pathway antibodies  ABC Transporters In Lipid Homeostasis Pathway Diagram
 ABC-family Proteins Mediated Transport Pathway antibodies  ABC-family Proteins Mediated Transport Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Fat Digestion And Absorption Pathway antibodies  Fat Digestion And Absorption Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
Diseases associated with anti-ABCG8 antibodyOrgans/Tissues associated with anti-ABCG8 antibody
 Disease Name  Pubmed Publications
 Dyslipidemias Antibodies  >84 publications with ABCG8 and Dyslipidemias
 Sitosterolemia Antibodies  >81 publications with ABCG8 and Sitosterolemia
 Atherosclerosis Antibodies  >81 publications with ABCG8 and Atherosclerosis
 Hyperlipidemias Antibodies  >79 publications with ABCG8 and Hyperlipidemias
 Liver Diseases Antibodies  >59 publications with ABCG8 and Liver Diseases
 Gallstones Antibodies  >45 publications with ABCG8 and Gallstones
 Fatty Liver Antibodies  >39 publications with ABCG8 and Fatty Liver
 Inflammation Antibodies  >21 publications with ABCG8 and Inflammation
 Coronary Artery Disease Antibodies  >19 publications with ABCG8 and Coronary Artery Disease
 Insulin Resistance Antibodies  >17 publications with ABCG8 and Insulin Resistance
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with ABCG8 and Muscle
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