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anti-ABHD4 antibody :: Goat ABHD4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420869 anti-ABHD4 antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABHD4, Polyclonal Antibody

 Also Known As   

Goat anti-ABHD4 (aa 304 to 316) Antibody

 Product Synonym Names    Goat Anti-ABHD4 (aa 177 to 187) Antibody; ABHD4; abhydrolase domain containing 4; FLJ12816; ABHD4 antibody; abhydrolase domain containing 4 antibody; FLJ12816 antibody; ABHD4 (aa 304 to 316)
 Product Gene Name   

anti-ABHD4 antibody

[Similar Products]
 Antibody/Peptide Pairs    ABHD4 peptide (MBS425050) is used for blocking the activity of ABHD4 antibody (MBS420869)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    QRPDSYVRDM EIK
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Human, Mouse, Rat, Dog
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-QRPDSYVRDMEIK, from the internal region of the protein sequence according to NP_071343.2.
 Epitope    Internal region
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-ABHD4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-ABHD4 antibody   

Peptide ELISA (EIA)

 Application Notes for anti-ABHD4 antibody    Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Preliminary experiments gave an approx 48kDa band in Human Brain (Cerebellum, Cerebellar Cortex, Frontal Cortex) lysates and in Mouse Brain lysates after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 38.8kDa according to NP_071343.2. The 48kDa band was successfully blocked by incubation with the immunizing peptide.
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NCBI/Uniprot data below describe general gene information for ABHD4. It may not necessarily be applicable to this product.
 NCBI GI #    50658087
 NCBI GeneID    63874
 NCBI Accession #    NP_071343.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022060.2 [Other Products]
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 UniProt Secondary Accession #    Q9H9E0; B4DDH7 [Other Products]
 UniProt Related Accession #    Q8TB40 [Other Products]
 Molecular Weight    20,239 Da
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 NCBI Official Full Name    protein ABHD4
 NCBI Official Synonym Full Names    abhydrolase domain containing 4
 NCBI Official Symbol    ABHD4 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    protein ABHD4
 UniProt Protein Name    Protein ABHD4
 UniProt Synonym Protein Names   
Alpha/beta hydrolase domain-containing protein 4
 Protein Family    Protein
 UniProt Gene Name    ABHD4 [Similar Products]
 UniProt Synonym Gene Names    Abhydrolase domain-containing protein 4 [Similar Products]
 UniProt Entry Name    ABHD4_HUMAN
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 UniProt Comments for ABHD4    ABHD4: Lysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine. Belongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.

Protein type: EC 3.1.1.-; Hydrolase

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: endoplasmic reticulum membrane; lipid particle

Molecular Function: hydrolase activity

Biological Process: lipid catabolic process; lipid metabolic process; phospholipid metabolic process; sequestering of lipid
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 Research Articles on ABHD4    1. ABHD4 is a novel genetic regulator of anoikis sensitivity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-ABHD4 antibodyOrgans/Tissues associated with anti-ABHD4 antibody
 Products by Pathway  Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Hydrolysis Of LPE Pathway antibodies  Hydrolysis Of LPE Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Phospholipid Metabolism Pathway antibodies  Phospholipid Metabolism Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with ABHD4 and Brain
 Prostate Antibodies  >1 publications with ABHD4 and Prostate
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