Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow ABHD5 rightarrow Polyclonal ABHD5  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • JAG1 Antibody
 • ALK Antibody
 • Collagen Type II (COL2) ELISA Kit
 • CFB ELISA Kit
 • hepatitis G virus (HGV) antigen ELISA Kit
 • Remnant lipoprotein cholesterol (RLP C) ELISA Kit
 • MacromoleculeAdiponectin (M-APN) ELISA Kit
 • CD134L-OX40L Antibody
 • sclerostin domain containing 1 (SOSTDC1) ELISA Kit
 • 3-phosphoinositide-dependen t protein kinase 1 (PDPK1) Recombinant Protein
 • 60S ribosomal protein L35a (RPL35A) Antibody
 • PRKD3 Antibody
 • Acetylcholine (ACH) ELISA Kit
 • LPIN1 Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-ABHD5 antibody :: Rabbit anti-Human ABHD5 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9409848
Unit / Price
0.1 mL  /  $255 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ABHD5, Polyclonal Antibody

 Also Known As   

ABHD5 Antibody

 Product Synonym Names    CDS; CGI58; IECN2; NCIE2
 Product Gene Name   

anti-ABHD5 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    275630
 3D Structure    ModBase 3D Structure for Q8WTS1
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Section Bar
 Specificity    The antibody detects endogenous levels of total ABHD5 protein.
 Purity/Purification    Antigen affinity purification.
 Form/Format    Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
 Concentration    0.5 mg/ml (lot specific)
Section Bar
 Immunogen Type    Recombinant Protein
 Immunogen Description    Fusion protein corresponding to residues near the C terminal of human Abhydrolase domain containing 5
 Target Name    ABHD5
Section Bar
 Preparation and Storage    Store at -20 degree C
 Other Notes    Small volumes of anti-ABHD5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 

Related Product Information for anti-ABHD5 antibody

   The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.
 Product Categories/Family for anti-ABHD5 antibody    Total protein Ab
 Applications Tested/Suitable for anti-ABHD5 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ABHD5 antibody    Western blotting: 1:200-1:1000
Immunohistochemistry: 1:15-1:50
Section Bar
 Testing Data of anti-ABHD5 antibody    Gel: 10%SDS-PAGE Lysate: 40ug A431 cell Primary antibody: 1/250 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 seconds
anti-ABHD5 antibody Testing Data image
Section Bar
 Immunohistochemistry (IHC) of anti-ABHD5 antibody    Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/10.
anti-ABHD5 antibody Immunohistochemistry (IHC) (IHC) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for ABHD5. It may not necessarily be applicable to this product.
 NCBI GI #    31542303
 NCBI GeneID    51099
 NCBI Accession #    NP_057090.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_016006.4 [Other Products]
Section Bar
 UniProt Primary Accession #    Q8WTS1 [Other Products]
 UniProt Secondary Accession #    Q9Y369; B2R9K0 [Other Products]
 UniProt Related Accession #    Q8WTS1 [Other Products]
 Molecular Weight    39,096 Da
Table BarTOPTable Bar
 NCBI Official Full Name    1-acylglycerol-3-phosphate O-acyltransferase ABHD5
 NCBI Official Synonym Full Names    abhydrolase domain containing 5
 NCBI Official Symbol    ABHD5 [Similar Products]
 NCBI Official Synonym Symbols   
CDS; CGI58; IECN2; NCIE2
[Similar Products]
 NCBI Protein Information    1-acylglycerol-3-phosphate O-acyltransferase ABHD5
 UniProt Protein Name    1-acylglycerol-3-phosphate O-acyltransferase ABHD5
 UniProt Synonym Protein Names   
Abhydrolase domain-containing protein 5; Lipid droplet-binding protein CGI-58
 Protein Family    1-acylglycerol-3-phosphate O-acyltransferase
 UniProt Gene Name    ABHD5 [Similar Products]
 UniProt Synonym Gene Names    NCIE2 [Similar Products]
 UniProt Entry Name    ABHD5_HUMAN
Section Bar
 NCBI Summary for ABHD5    The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for ABHD5    ABHD5: a lysophosphatidic acid acyltransferase which functions in phosphatidic acid biosynthesis. May regulate the cellular storage of triacylglycerol through activation of the phospholipase PNPLA2. Involved in keratinocyte differentiation. Colocalized with PLIN and ADFP on the surface of lipid droplets. The localization is dependent upon the metabolic status of the adipocytes and the activity of PKA. Defects cause neutral lipid storage disease (NLSD), an autosomal recessive disorder characterized by the excessive accumulation of neutral lipids in multiple tissues, and Chanarin-Dorfman syndrome (CDS), a triglyceride storage disease with impaired long-chain fatty acid oxidation and icthyosis. CDS is an autosomal recessive inborn error of lipid metabolism with multisystemic accumulation of triglycerides although plasma concentrations are normal. Widely expressed in various tissues, including lymphocytes, liver, skeletal muscle and brain. Expressed by upper epidermal layers and dermal fibroblasts in skin, hepatocytes and neurons.

Protein type: Lipase; EC 2.3.1.51; Transferase

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: intracellular membrane-bound organelle; cytoplasm; lipid particle; cytosol; nucleus

Molecular Function: triacylglycerol lipase activity; lysophosphatidic acid acyltransferase activity; 1-acylglycerol-3-phosphate O-acyltransferase activity

Biological Process: triacylglycerol catabolic process; phosphatidic acid biosynthetic process; positive regulation of lipoprotein lipase activity; fatty acid metabolic process; cell differentiation

Disease: Chanarin-dorfman Syndrome
Table BarTOPTable Bar
 Research Articles on ABHD5    1. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin 1A-coated lipid droplets
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-ABHD5 antibodyPathways associated with anti-ABHD5 antibody
 Reference Product  PubMed Publications
 PNPLA2 antibody  >31 publications with ABHD5 and PNPLA2
 PLIN5 antibody  >4 publications with ABHD5 and PLIN5
 PLIN1 antibody  >4 publications with ABHD5 and PLIN1
 PNPLA3 antibody  >3 publications with ABHD5 and PNPLA3
 PNPLA4 antibody  >1 publications with ABHD5 and PNPLA4
 PLIN2 antibody  >1 publications with ABHD5 and PLIN2
 Products by Pathway  Pathway Diagram
 CDP-diacylglycerol Biosynthesis Pathway antibodies  CDP-diacylglycerol Biosynthesis Pathway Diagram
 Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway antibodies  Hormone-sensitive Lipase (HSL)-mediated Triacylglycerol Hydrolysis Pathway Diagram
 Lipid Digestion, Mobilization, And Transport Pathway antibodies  Lipid Digestion, Mobilization, And Transport Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Regulation Of Lipolysis In Adipocytes Pathway antibodies  Regulation Of Lipolysis In Adipocytes Pathway Diagram
 Triacylglycerol Biosynthesis Pathway antibodies  Triacylglycerol Biosynthesis Pathway Diagram
Diseases associated with anti-ABHD5 antibodyOrgans/Tissues associated with anti-ABHD5 antibody
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >30 publications with ABHD5 and Fatty Liver
 Liver Diseases Antibodies  >27 publications with ABHD5 and Liver Diseases
 Triglyceride storage disease with impaired long-chain fatty acid oxidation Antibodies  >12 publications with ABHD5 and Triglyceride storage disease with impaired long-chain fatty acid oxidation
 Inflammation Antibodies  >8 publications with ABHD5 and Inflammation
 Hepatomegaly Antibodies  >7 publications with ABHD5 and Hepatomegaly
 Cardiovascular Diseases Antibodies  >7 publications with ABHD5 and Cardiovascular Diseases
 Heart Diseases Antibodies  >6 publications with ABHD5 and Heart Diseases
 Necrosis Antibodies  >5 publications with ABHD5 and Necrosis
 Hypertrophy Antibodies  >4 publications with ABHD5 and Hypertrophy
 Weight Gain Antibodies  >4 publications with ABHD5 and Weight Gain
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >42 publications with ABHD5 and Liver
 Muscle Antibodies  >25 publications with ABHD5 and Muscle
 Connective Tissue Antibodies  >23 publications with ABHD5 and Connective Tissue
 Blood Antibodies  >20 publications with ABHD5 and Blood
 Skin Antibodies  >20 publications with ABHD5 and Skin
 Heart Antibodies  >9 publications with ABHD5 and Heart
 Intestine Antibodies  >4 publications with ABHD5 and Intestine
 Bone Antibodies  >4 publications with ABHD5 and Bone
 Kidney Antibodies  >3 publications with ABHD5 and Kidney
 Bone Marrow Antibodies  >3 publications with ABHD5 and Bone Marrow
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions