NP_001128658.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
38,450 Da
NCBI Official Full Name
ABI gene family member 3 isoform 2
NCBI Official Synonym Full Names
ABI family member 3
NCBI Protein Information
ABI gene family member 3
UniProt Protein Name
ABI gene family member 3
UniProt Synonym Protein Names
New molecule including SH3; Nesh
UniProt Synonym Gene Names
UniProt Entry Name
ABI3_HUMAN
NCBI Summary for ABI3
This gene encodes a member of an adaptor protein family. Members of this family encode proteins containing a homeobox homology domain, proline rich region and Src-homology 3 (SH3) domain, and are components of the Abi/WAVE complex which regulates actin polymerization. The encoded protein inhibits ectopic metastasis of tumor cells as well as cell migration. This may be accomplished through interaction with p21-activated kinase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
UniProt Comments for ABI3
ABI3: May inhibit tumor metastasis. In vitro, reduces cell motility. Belongs to the ABI family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 17q21.3
Cellular Component: cytoplasm; intracellular; lamellipodium; membrane
Molecular Function: protein binding
Biological Process: cell motility; peptidyl-tyrosine phosphorylation; regulation of cell migration
Research Articles on ABI3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-ABI3 antibody
Diseases associated with anti-ABI3 antibody
Organs/Tissues associated with anti-ABI3 antibody
|