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anti-ACADS antibody :: Rabbit ACADS Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS125363
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

ACADS, Polyclonal Antibody

 Also Known As   

ACADS Polyclonal Antibody

 Product Synonym Names    ACAD3; SCAD
 Product Gene Name   

anti-ACADS antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    phenotype 606885
 3D Structure    ModBase 3D Structure for P16219
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Monkey
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 Purity/Purification    Affinity Purification
 Concentration    1mg/ml (lot specific)
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 Species    Human
 Immunogen    Recombinant Protein
 Immunogen    Fusion protein of human ACADS
 Calculated Molecular Weight    44kDa
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 Preparation and Storage    Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-ACADS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-ACADS antibody

   This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. [provided by RefSeq, Jul 2008]
 Product Categories/Family for anti-ACADS antibody    Polyclonal
 Applications Tested/Suitable for anti-ACADS antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-ACADS antibody    WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
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 Western Blot (WB) of anti-ACADS antibody    Western blot analysis of extracts of various cell lines, using ACADS antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 15s.
anti-ACADS antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-ACADS antibody    Immunohistochemistry of paraffin-embedded human liver cancer using ACADS antibody at dilution of 1:100 (40x lens).
anti-ACADS antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-ACADS antibody    Immunohistochemistry of paraffin-embedded human liver injury using ACADS antibody at dilution of 1:100 (40x lens).
anti-ACADS antibody Immunohistochemistry (IHC) (IHC) image
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 Immunofluorescence (IF) of anti-ACADS antibody    Immunofluorescence analysis of U2OS cells using ACADS antibody. Blue: DAPI for nuclear staining.
anti-ACADS antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for ACADS. It may not necessarily be applicable to this product.
 NCBI GI #    113019
 NCBI GeneID    35
 NCBI Accession #    P16219.1 [Other Products]
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 UniProt Primary Accession #    P16219 [Other Products]
 UniProt Secondary Accession #    P78331 [Other Products]
 UniProt Related Accession #    P16219 [Other Products]
 Molecular Weight    412
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 NCBI Official Full Name    Short-chain specific acyl-CoA dehydrogenase, mitochondrial
 NCBI Official Synonym Full Names    acyl-CoA dehydrogenase, C-2 to C-3 short chain
 NCBI Official Symbol    ACADS [Similar Products]
 NCBI Official Synonym Symbols   
SCAD; ACAD3
[Similar Products]
 NCBI Protein Information    short-chain specific acyl-CoA dehydrogenase, mitochondrial; butyryl-CoA dehydrogenase; unsaturated acyl-CoA reductase; acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain; mitochondrial short-chain specific acyl-CoA dehydrogenase
 UniProt Protein Name    Short-chain specific acyl-CoA dehydrogenase, mitochondrial
 UniProt Synonym Protein Names   
Butyryl-CoA dehydrogenase
 Protein Family    Short-chain specific acyl-CoA dehydrogenase
 UniProt Gene Name    ACADS [Similar Products]
 UniProt Synonym Gene Names    SCAD [Similar Products]
 UniProt Entry Name    ACADS_HUMAN
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 NCBI Summary for ACADS    This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms. [provided by RefSeq, Oct 2014]
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 UniProt Comments for ACADS    ACADS: Defects in ACADS are the cause of acyl-CoA dehydrogenase short-chain deficiency (ACADSD). It is an autosomal recessive disorder resulting in acute acidosis and muscle weakness in infants, and a form of lipid-storage myopathy in adults. Belongs to the acyl-CoA dehydrogenase family.

Protein type: Lipid Metabolism - fatty acid; Mitochondrial; Carbohydrate Metabolism - butanoate; Oxidoreductase; EC 1.3.8.1; Amino Acid Metabolism - valine, leucine and isoleucine degradation

Chromosomal Location of Human Ortholog: 12q24.31

Cellular Component: mitochondrion; mitochondrial matrix; mitochondrial membrane; nucleus

Molecular Function: acyl-CoA dehydrogenase activity; butyryl-CoA dehydrogenase activity; FAD binding; acyl-CoA binding

Biological Process: response to starvation; fatty acid beta-oxidation; response to glucocorticoid stimulus; cellular lipid metabolic process; fatty acid beta-oxidation using acyl-CoA dehydrogenase; butyrate catabolic process; protein homotetramerization

Disease: Acyl-coa Dehydrogenase, Short-chain, Deficiency Of
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 Research Articles on ACADS    1. IVD mutations in Asian populations are distinct from these in Western populations.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-ACADS antibodyPathways associated with anti-ACADS antibody
 Reference Product  PubMed Publications
 ECHS1 antibody  >3 publications with ACADS and ECHS1
 ACAA2 antibody  >2 publications with ACADS and ACAA2
 ACSM3 antibody  >1 publications with ACADS and ACSM3
 GCDH antibody  >1 publications with ACADS and GCDH
 ACAT2 antibody  >1 publications with ACADS and ACAT2
 EHHADH antibody  >1 publications with ACADS and EHHADH
 ACAT1 antibody  >1 publications with ACADS and ACAT1
 Products by Pathway  Pathway Diagram
 Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway antibodies  Beta Oxidation Of Butanoyl-CoA To Acetyl-CoA Pathway Diagram
 Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway antibodies  Beta Oxidation Of Hexanoyl-CoA To Butanoyl-CoA Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Carbon Metabolism Pathway antibodies  Carbon Metabolism Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Degradation Pathway antibodies  Fatty Acid Degradation Pathway Diagram
 Fatty Acid Metabolism Pathway antibodies  Fatty Acid Metabolism Pathway Diagram
Diseases associated with anti-ACADS antibodyOrgans/Tissues associated with anti-ACADS antibody
 Disease Name  Pubmed Publications
 Short chain Acyl CoA dehydrogenase deficiency Antibodies  >9 publications with ACADS and Short chain Acyl CoA dehydrogenase deficiency
 Fatty Liver Antibodies  >6 publications with ACADS and Fatty Liver
 Liver Diseases Antibodies  >5 publications with ACADS and Liver Diseases
 Death Antibodies  >4 publications with ACADS and Death
 Brain Diseases Antibodies  >4 publications with ACADS and Brain Diseases
 Nervous System Diseases Antibodies  >2 publications with ACADS and Nervous System Diseases
 Heart Diseases Antibodies  >2 publications with ACADS and Heart Diseases
 Fatty Liver, Alcoholic Antibodies  >1 publications with ACADS and Fatty Liver, Alcoholic
 Disease Models, Animal Antibodies  >1 publications with ACADS and Disease Models, Animal
 Hyperplasia Antibodies  >1 publications with ACADS and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >11 publications with ACADS and Liver
 Muscle Antibodies  >8 publications with ACADS and Muscle
 Brain Antibodies  >7 publications with ACADS and Brain
 Blood Antibodies  >6 publications with ACADS and Blood
 Kidney Antibodies  >3 publications with ACADS and Kidney
 Connective Tissue Antibodies  >3 publications with ACADS and Connective Tissue
 Nerve Antibodies  >2 publications with ACADS and Nerve
 Prostate Antibodies  >1 publications with ACADS and Prostate
 Skin Antibodies  >1 publications with ACADS and Skin
 Intestine Antibodies  >1 publications with ACADS and Intestine
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