View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-ACE1 antibody :: Rabbit anti-Human, Mouse ACE1 Polyclonal Antibody Catalog # MBS4751149 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name ACE1, Polyclonal Antibody Full Product Name Anti-ACE1 Rabbit pAb Product Synonym Names Angiotensin-converting enzyme; somatic isoform precursor; CD143 antigen; DCP; DCP1; Dipeptidyl carboxypeptidase I; Kininase II Product Gene Name anti-ACE1 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 106180 3D Structure ModBase 3D Structure for P12821 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse Specificity ACE1 Antibody detects endogenous levels of total ACE1 Purity/Purification Affinity Chromatography Form/Format Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Immunogen A synthesized peptide derived from human ACE1 Subcellular Location Cytoplasm Preparation and Storage Store at 4 degree C for short term.Store at-20 degree C for long term.Avoid freeze/thaw cycle. Other Notes Small volumes of anti-ACE1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-ACE1 antibody Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. Applications Tested/Suitable for anti-ACE1 antibody Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) Application Notes for anti-ACE1 antibody WB: 1:500-1:1000IHC: 1:50-1:200FC/FACS: 1:30 Western Blot (WB) of anti-ACE1 antibody Western blot analysis of ACE1 expression in human fetal kidney lysate. TOP NCBI/Uniprot data below describe general gene information for ACE1. It may not necessarily be applicable to this product. NCBI GI # 4503273 NCBI GeneID 1636 NCBI Accession # NP_000780.1 [Other Products] NCBI GenBank Nucleotide # NM_000789.3 [Other Products] UniProt Primary Accession # P12821 [Other Products] UniProt Secondary Accession # P22966; Q53YX9; Q59GY8; Q7M4L4; B0LPF0; B4DXI3; E7EU16[Other Products] UniProt Related Accession # P12821[Other Products] Molecular Weight 195kDa TOP NCBI Official Full Name angiotensin-converting enzyme isoform 1 NCBI Official Synonym Full Names angiotensin I converting enzyme NCBI Official Symbol ACE [Similar Products] NCBI Official Synonym Symbols DCP; ACE1; DCP1; CD143 [Similar Products] NCBI Protein Information angiotensin-converting enzyme UniProt Protein Name Angiotensin-converting enzyme UniProt Synonym Protein Names Dipeptidyl carboxypeptidase I; Kininase II; CD_antigen: CD143 Protein Family Zinc finger transcription factor UniProt Gene Name ACE [Similar Products] UniProt Synonym Gene Names DCP; DCP1; ACE [Similar Products] TOP NCBI Summary for ACE1 This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010] TOP UniProt Comments for ACE1 Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. Research Articles on ACE1 1. The ACE I/D polymorphism (rs4340) may contribute to the genetic susceptibility of community-acquired pneumonia (CAP) in Egyptian children. The ACE D allele and DD genotype were associated with higher serum ACE levels among studied CAP patients. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-ACE1 antibody Reference Product PubMed Publications AGT antibody >423 publications with ACE1 and AGT ACE2 antibody >410 publications with ACE1 and ACE2 SERPINE1 antibody >191 publications with ACE1 and SERPINE1 NOS3 antibody >143 publications with ACE1 and NOS3 REN antibody >129 publications with ACE1 and REN FOS antibody >42 publications with ACE1 and FOS CTGF antibody >19 publications with ACE1 and CTGF VEGFA antibody >14 publications with ACE1 and VEGFA ATP6AP2 antibody >8 publications with ACE1 and ATP6AP2 KNG1 antibody >1 publications with ACE1 and KNG1 Pathways associated with anti-ACE1 antibody Products by Pathway Pathway Diagram ACE Inhibitor Pathway antibodies ACE Inhibitor Pathway Diagram Chagas Disease (American Trypanosomiasis) Pathway antibodies Chagas Disease (American Trypanosomiasis) Pathway Diagram Chagas Disease (American Trypanosomiasis) Pathway antibodies Chagas Disease (American Trypanosomiasis) Pathway Diagram Hypertrophic Cardiomyopathy (HCM) Pathway antibodies Hypertrophic Cardiomyopathy (HCM) Pathway Diagram Hypertrophic Cardiomyopathy (HCM) Pathway antibodies Hypertrophic Cardiomyopathy (HCM) Pathway Diagram Metabolism Of Angiotensinogen To Angiotensins Pathway antibodies Metabolism Of Angiotensinogen To Angiotensins Pathway Diagram Metabolism Of Proteins Pathway antibodies Metabolism Of Proteins Pathway Diagram Peptide Hormone Metabolism Pathway antibodies Peptide Hormone Metabolism Pathway Diagram Renin-angiotensin System Pathway antibodies Renin-angiotensin System Pathway Diagram Renin-angiotensin System Pathway antibodies Renin-angiotensin System Pathway Diagram Diseases associated with anti-ACE1 antibody Disease Name Pubmed Publications Cardiovascular Diseases Antibodies >13338 publications with ACE1 and Cardiovascular Diseases Hypertension Antibodies >8569 publications with ACE1 and Hypertension Heart Failure Antibodies >4522 publications with ACE1 and Heart Failure Kidney Diseases Antibodies >3364 publications with ACE1 and Kidney Diseases Myocardial Infarction Antibodies >2505 publications with ACE1 and Myocardial Infarction Coronary Artery Disease Antibodies >2153 publications with ACE1 and Coronary Artery Disease Coronary Disease Antibodies >2137 publications with ACE1 and Coronary Disease Stroke Antibodies >1354 publications with ACE1 and Stroke Renal Insufficiency Antibodies >1277 publications with ACE1 and Renal Insufficiency Respiratory Tract Diseases Antibodies >1235 publications with ACE1 and Respiratory Tract Diseases Organs/Tissues associated with anti-ACE1 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >11740 publications with ACE1 and Blood Heart Antibodies >8047 publications with ACE1 and Heart Vascular Antibodies >4459 publications with ACE1 and Vascular Kidney Antibodies >4087 publications with ACE1 and Kidney Muscle Antibodies >2120 publications with ACE1 and Muscle Lung Antibodies >1542 publications with ACE1 and Lung Brain Antibodies >1237 publications with ACE1 and Brain Intestine Antibodies >264 publications with ACE1 and Intestine Eye Antibodies >230 publications with ACE1 and Eye Testis Antibodies >223 publications with ACE1 and Testis TOP © 2006-24 MyBioSource.com. 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