NP_068576.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
92kDa, 100kDa
NCBI Official Full Name
angiotensin-converting enzyme 2
NCBI Official Synonym Full Names
angiotensin I converting enzyme 2
NCBI Official Synonym Symbols
NCBI Protein Information
angiotensin-converting enzyme 2
UniProt Protein Name
Angiotensin-converting enzyme 2
UniProt Synonym Protein Names
ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; ACEH
UniProt Synonym Gene Names
NCBI Summary for ACE2
The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. [provided by RefSeq, Jul 2008]
UniProt Comments for ACE2
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function.
Research Articles on ACE2
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Products associated with anti-ACE2 antibody
Pathways associated with anti-ACE2 antibody
Diseases associated with anti-ACE2 antibody
Organs/Tissues associated with anti-ACE2 antibody
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