NP_057641.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,914 Da
NCBI Official Full Name
atypical chemokine receptor 4
NCBI Official Synonym Full Names
atypical chemokine receptor 4
NCBI Official Synonym Symbols
PPR1; CCBP2; CCR10; CCR11; CCRL1; VSHK1; CCR-11; CKR-11; CCX CKR; CCX-CKR; CC-CKR-11 [Similar Products]
NCBI Protein Information
atypical chemokine receptor 4; C-C CKR-11; CC chemokine receptor-like 1; C-C chemokine receptor type 11; chemocentryx chemokine receptor; chemokine (C-C motif) receptor-like 1; chemokine, cc motif, receptor-like protein 1; orphan seven-transmembrane receptor, chemokine related
UniProt Protein Name
Atypical chemokine receptor 4
UniProt Synonym Protein Names
C-C chemokine receptor type 11; C-C CKR-11; CC-CKR-11; CCR-11; CC chemokine receptor-like 1; CCRL1; CCX CKR
UniProt Synonym Gene Names
CCBP2; CCR11; CCRL1; VSHK1; C-C CKR-11; CC-CKR-11; CCR-11; CCRL1 [Similar Products]
UniProt Entry Name
ACKR4_HUMAN
NCBI Summary for ACKR4
The protein encoded by this gene is a member of the G protein-coupled receptor family, and is a receptor for C-C type chemokines. This receptor has been shown to bind dendritic cell- and T cell-activated chemokines including CCL19/ELC, CCL21/SLC, and CCL25/TECK. A pseudogene of this gene is found on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2013]
UniProt Comments for ACKR4
CCRL1: Receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q22
Cellular Component: recycling endosome; integral to plasma membrane; early endosome; plasma membrane
Molecular Function: protein binding; chemokine binding; chemokine receptor activity; scavenger receptor activity
Biological Process: receptor-mediated endocytosis; G-protein coupled receptor protein signaling pathway; immune response; chemotaxis
Research Articles on ACKR4
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Products associated with anti-ACKR4 antibody
Pathways associated with anti-ACKR4 antibody
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